Top 100 The Binding of Isaac: Rebirth Videos With The Most Comments by Edit:EdTop 100 » 200 » 300 » 400 » 500Video TitleCommentsCategoryGame1.Let's Play The Binding Of Isaac Afterbirth: (Episode 5) - THIS BASEMENT SHALL BE YOUR TOMB25Let's PlayThe Binding of Isaac: Rebirth 2.UPDATE: Let's Play The Binding Of Isaac Rebirth: OverEnglishMan Sickness Special23The Binding of Isaac: Rebirth 3.Let's Play The Binding Of Isaac Afterbirth: (Episode 4) - QUAD LOST14Let's PlayThe Binding of Isaac: Rebirth 4.LARDY LILITH VS. AFTERBIRTH! - Let's Play The Binding Of Isaac Afterbirth: (Episode 3)8Let's PlayThe Binding of Isaac: Rebirth 5.Let's Play The Binding Of Isaac Rebirth: (Episode 2) - THE PLATINUM GOD REBORN! (Playthrough)6Let's PlayThe Binding of Isaac: Rebirth Top 100 » 200 » 300 » 400 » 500