| 1. | This New Glitched Dice Almost Broke My Game! | 47 | |
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| 2. | This New Item Gives You Super Homing Tears! | 180 | |
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| 3. | I Got The Craziest Rerolls With This New Dice! | 55 | |
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| 4. | The Luckiest Isaac Run I've Ever Had! | 77 | | The Binding of Isaac: Rebirth
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| 5. | This New Dice Gives You The Best Items! | 47 | |
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| 6. | This New Item Has The Craziest Synergies! | 109 | |
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| 7. | This New Secret Ending Is Insane! | 201 | |
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| 8. | These New Isaac Unlocks Are INSANE! | 158 | | The Binding of Isaac: Rebirth
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| 9. | Playable Blood Donation Machine Is Too Horrifying! | 553 | | The Binding of Isaac: Rebirth
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| 10. | Isaac, But He's Addicted To 'Sugar'... | 122 | | The Binding of Isaac: Rebirth
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| 11. | I Created My Own Super Meat Boy Army! | 72 | | Super Meat Boy
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| 12. | This New Upgraded Sacred Orb Is INSANE! | 110 | |
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| 13. | I Finally Found The Perfect Gambling Character! | 78 | |
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| 14. | Isaac Run, But Every Item Is A Golden Horse Pill... | 217 | | The Binding of Isaac: Rebirth
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| 15. | They Turned Slot Machine Into A Character?! It's INSANE! | 154 | | The Binding of Isaac: Rebirth
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| 16. | This New Character Gets Stats For Every Kill! | 124 | |
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| 17. | This New Item Turns You Into True Werewolf! | 93 | |
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| 18. | These New Greedier Bosses Are Absolutely Incredible! | 108 | |
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| 19. | They Added Playable Confessional! It's INCREDIBLE! | 278 | |
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| 20. | I Found The Most Broken Room In Isaac History! | 78 | | The Binding of Isaac: Rebirth
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| 21. | This New Damocles Sword Is Extremely Risky... | 231 | | Damocles
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| 22. | These New Akeldama Synergies Are Absolutely BROKEN! | 123 | |
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| 23. | This New Character Can Create Isaac Army! | 118 | | The Binding of Isaac: Rebirth
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| 24. | This New Devil Item Gives You Infinite Stats! | 89 | | The Binding of Isaac: Rebirth
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| 25. | This New Technology Item Almost Crashed My Game! | 101 | |
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| 26. | This New Character Can Create Familiars! Tainted Siren Gameplay! | 101 | | The Binding of Isaac: Rebirth
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| 27. | How I Killed Delirium In Literally One Frame! | 46 | | The Binding of Isaac: Rebirth
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| 28. | This New Character Can Spawn Army Of Zombies! | 164 | | The Binding of Isaac: Rebirth
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| 29. | I Finally Got The Biggest Brimstone In Isaac History! | 120 | | The Binding of Isaac: Rebirth
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| 30. | Isaac, But He Has Finally Grown Up! | 122 | | The Binding of Isaac: Rebirth
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| 31. | This New Item Literally Destroyed My Shops! | 88 | |
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| 32. | This New Dice Hits The Luckiest Rerolls Ever! | 79 | |
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| 33. | I Finally Got The Craziest Tainted Samael Synergy! | 85 | | The Binding of Isaac: Rebirth
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| 34. | This New Keeper Challenge Is Extremely Hard! | 161 | | The Binding of Isaac: Rebirth
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| 35. | Tainted Delirium Is Insanely Hard... | 267 | |
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| 36. | New Upgraded Mutant Spider Is Extremely Powerful! | 157 | |
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| 37. | I Found The Best Familiar In The Game! It's CRAZY! | 93 | | The Binding of Isaac: Rebirth
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| 38. | This New Godhead Is Absolutely Broken! | 78 | |
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| 39. | This New Item Creates Completely New Broken Shops! | 53 | | The Binding of Isaac: Rebirth
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| 40. | This New Golden Keeper Is Extremely Greedy! | 124 | |
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| 41. | This New Cyborg Transformation Is Literally BROKEN! | 126 | | The Binding of Isaac: Rebirth
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| 42. | This New Item Almost Crashed My Game! | 158 | |
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| 43. | They Made Playable Duke Of Flies! It's Extremely Cute! | 120 | |
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| 44. | I Got The Luckiest Upgrade In Isaac History! | 61 | |
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| 45. | Playable Santa Is Insanely Overpowered! | 86 | |
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| 46. | This New Quality 4 Gives You The Best Items In The Game! | 141 | |
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| 47. | Isaac, But Every Enemy Is Also Isaac | 172 | | The Binding of Isaac: Rebirth
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| 48. | Can I Survive With Isaac's Heart As Tainted Lost? | 80 | | The Binding of Isaac: Rebirth
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| 49. | This New Item Makes Everything Literally BROKEN! | 32 | | The Binding of Isaac: Rebirth
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| 50. | I Played The Most Violent Isaac Challenge! | 106 | |
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| 51. | They Turned The Entire Solar System Into A Character! It's INSANE! | 243 | |
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| 52. | I Tried Mega D6 And It's Mega BROKEN! | 55 | |
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| 53. | These New Sacrifice Rooms Are Completely Broken! | 94 | |
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| 54. | This New Lilith Has Insane LUCK! | 119 | |
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| 55. | I Tried The Most Broken Character In Isaac History... | 56 | | The Binding of Isaac: Rebirth
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| 56. | This New Item Gave Me The Most Chaotic Tears Ever! | 122 | |
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| 57. | Isaac Run, But Every Room I Get A New Character! | 79 | | The Binding of Isaac: Rebirth
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| 58. | New Way Of Unlocking Tarnished Judas Is Too Scary! | 104 | |
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| 59. | The Hardest Character Ever Made! Tainted Xaphan Gameplay! | 161 | |
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| 60. | The Craziest Character I've Ever Played! Tainted Zoe Gameplay! | 126 | |
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| 61. | I Finally Played As Pure Judas! He's Completely BROKEN! | 293 | |
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| 62. | This New Character Has Craziest Items! Researcher Gameplay! | 201 | |
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| 63. | This Reworked Golden Razor Gives Insane Damage! | 95 | |
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| 64. | New Final Boss And New Ending! Unlocking Secret Character In Isaac! | 262 | | The Binding of Isaac: Rebirth
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| 65. | Alcoholic Catgirl Is Ridiculously Drunk! | 140 | |
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| 66. | New Reworked Tarnished Judas Is INSANE! | 160 | |
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| 67. | This New Character Can't Take ANY Items! | 131 | |
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| 68. | This New Character Has Crazy Abilities! Sin Gameplay! | 142 | | SiN
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| 69. | This New Quality 4 Item Has INSANE Synergies! | 452 | | The Binding of Isaac: Rebirth
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| 70. | These New Alternative Final Bosses Are Crazy Hard! | 125 | | The Binding of Isaac: Rebirth
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| 71. | This New Secret Miniboss Is Too Horrifying! | 175 | |
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| 72. | This New Item Turns Everything Into GOLD! | 125 | | The Binding of Isaac: Rebirth
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| 73. | Early Version Of Tainted Eden Is Extremely Glitched... | 124 | |
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| 74. | This Devil Deal Literally Broke My Game! | 77 | |
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| 75. | This New Item Gave Me The Best Familiars! | 78 | |
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| 76. | This Crazy Glitch Almost Ruined My Run! | 40 | |
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| 77. | This New Character Can Literally Dupe Items! | 56 | |
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| 78. | This New Item Turns Isaac Into Scariest Boss! | 115 | | The Binding of Isaac: Rebirth
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| 79. | They Added New Technology Item! It's Extremely Powerful! | 80 | |
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| 80. | This New Item Changes Your Tears With Giant Brimstone! | 111 | | The Binding of Isaac: Rebirth
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| 81. | Isaac, But Every Time I Die I Get More Stats! | 62 | | The Binding of Isaac: Rebirth
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| 82. | This New Character Has Electric Brimstone! Zoe Gameplay! | 149 | | Brimstone
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| 83. | I Created My Own Immortal Mini Isaac Army! | 94 | | The Binding of Isaac: Rebirth
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| 84. | What Happens If I Void Every Active Item In The Game?! | 66 | |
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| 85. | Tainted Lost Double Brimstone Run | 90 | | Brimstone
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| 86. | This New Dice Literally Broke My Game! | 70 | | The Binding of Isaac
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| 87. | They Added A New Beggar To The Game! He's Hilarious! | 168 | |
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| 88. | The Craziest Character Ever Made! Tarnished Blue Baby Gameplay! | 93 | |
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| 89. | This Item Should've Never Been Added To Isaac... | 82 | | The Binding of Isaac
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| 90. | This New Item Gave Me Insane Damage! | 133 | | The Binding of Isaac: Rebirth
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| 91. | This New Dice Completely Broke My Game! | 113 | |
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| 92. | They Made Delirious Isaac. He's literally BROKEN! | 149 | | The Binding of Isaac: Rebirth
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| 93. | I Faced A New Final Boss From Heaven's Call Mod! (AND ALMOST DIED) | 350 | |
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| 94. | I Tried The Riskiest Item In Isaac! It's INSANE! | 80 | | The Binding of Isaac: Rebirth
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| 95. | This Trinket Adds Unique Effects For Every Character! | 113 | |
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| 96. | I Tried The Darkest Challenge In Isaac! | 74 | | The Binding of Isaac: Rebirth
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| 97. | They Added Playable Donation Machine To The Game! It Was A Mistake. | 174 | |
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| 98. | Isaac Will Never Be The Same Again... | 100 | | The Binding of Isaac: Rebirth
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| 99. | THIS Will Give You Every Angel Item In The Game! | 122 | |
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| 100. | Jacob And Esau Run, But Only One Takes All The Items! | 60 | |
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