| 1. | The Hardest Character Ever Made? Fiend Folio Challenge #1 | 70,041 | | The Binding of Isaac: Rebirth
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| 2. | The Most Fragile Character In The Game!? Fiend Folio Challenge #4 | 66,744 | | The Binding of Isaac: Rebirth
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| 3. | New Way Of Unlocking Tarnished Isaac Is Too Horrifying! | 48,177 | | The Binding of Isaac: Rebirth
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| 4. | This Secret Fiend Folio Character Will Destroy Your Hand! Fend Gameplay! | 43,979 | | The Binding of Isaac: Rebirth
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| 5. | This Secret Fiend Folio Character Is The Hardest I've Ever Played! China Gameplay! | 31,665 | | The Binding of Isaac: Rebirth
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| 6. | This Tainted Godhead Is Better Than The Regular One! | 30,359 | | The Binding of Isaac: Rebirth
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| 7. | This Secret Fiend Folio Character Will Blow Your Mind! Fient Gameplay! | 24,235 | | The Binding of Isaac: Rebirth
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| 8. | What Happens If Golem Takes Rock Bottom On The First Floor? | 24,011 | | The Binding of Isaac: Rebirth
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| 9. | Can I Survive Without Taking Items?! Rock Bottom + D8 Custom Challenge! | 20,421 | | The Binding of Isaac: Rebirth
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| 10. | Playable Blood Donation Machine Is Too Horrifying! | 18,606 | | The Binding of Isaac: Rebirth
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| 11. | This New Quality 4 Item Has INSANE Synergies! | 18,192 | | The Binding of Isaac: Rebirth
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| 12. | They Added Tainted Sheriff And He's AMAZING! | 16,659 | | The Binding of Isaac: Rebirth
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| 13. | I Got 2 Bricks Instead Of Tears?! Fiend Folio Challenge #6 | 16,509 | | The Binding of Isaac: Rebirth
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| 14. | This Fiend Folio Secret Character Is Absolutely Out Of Control! Slippy Gameplay! | 15,659 | | The Binding of Isaac: Rebirth
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| 15. | These New Tainted Items Are Insane! Tainted Treasure Rooms Mod! | 15,325 | | The Binding of Isaac: Rebirth
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| 16. | You Need Only ONE TRINKET To Completely Break Greedier! | 12,818 | | The Binding of Isaac: Rebirth
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| 17. | Tower Offense In Isaac? Fiend Folio Challenge #3 | 12,817 | | The Binding of Isaac: Rebirth
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| 18. | Isaac VS All Fiend Folio Bosses! Fiend Folio Challenge #5 | 12,194 | | The Binding of Isaac: Rebirth
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| 19. | This Item Allows You Go Through The Walls! Fiend Folio Challenge #12 | 11,654 | | The Binding of Isaac: Rebirth
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| 20. | I Faced A New Final Boss From Heaven's Call Mod! (AND ALMOST DIED) | 11,010 | |
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| 21. | I Got Knives Instead Of Tears!? Trying Tainted Fiend For The First Time! | 10,920 | | The Binding of Isaac: Rebirth
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| 22. | Waiting for Tarnished Lost to release be like: #shorts | 10,652 | | The Binding of Isaac: Rebirth
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| 23. | I Got Golden Rock Bottom! Luckiest Tarnished Keeper Start Ever! | 10,475 | | The Binding of Isaac: Rebirth
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| 24. | These New Alternative Minibosses Are CRAZY! | 9,890 | |
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| 25. | This New Rock Bottom Almost Destroyed My PC! | 9,278 | | The Binding of Isaac: Rebirth
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| 26. | Can I Escape From The Real Jon?! Fiend Folio Challenge #9 | 8,520 | | The Binding of Isaac: Rebirth
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| 27. | I Opened Every Single Room In Isaac With This New Item! | 8,374 | | The Binding of Isaac: Rebirth
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| 28. | How Did I Get A This In Isaac!? Golem Run Gone Wrong! | 8,369 | | The Binding of Isaac: Rebirth
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| 29. | They Made Playable Hush And It's Too BROKEN! | 8,246 | | The Binding of Isaac: Rebirth
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| 30. | I Finally Played As Pure Judas! He's Completely BROKEN! | 8,051 | |
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| 31. | This New Keeper's Penny Upgrades Shops To The Next Level! | 7,978 | | The Binding of Isaac: Rebirth
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| 32. | Tainted Delirium Is Insanely Hard... | 7,863 | |
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| 33. | This New Quality 4 Item Creates Boss Crawlspaces! | 7,825 | | The Binding of Isaac: Rebirth
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| 34. | What Happens If I Take Every Technology Item In The Game?! | 7,688 | Vlog | The Binding of Isaac: Rebirth
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| 35. | Can I Survive Doing This Crooked Penny Custom Challenge?! | 7,642 | | The Binding of Isaac: Rebirth
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| 36. | They Added Playable Confessional! It's INCREDIBLE! | 7,640 | |
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| 37. | What Happens If I Void Every Item I See? Apollyon Custom Challenge! | 7,378 | | The Binding of Isaac: Rebirth
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| 38. | This New Polyphemus Gave Me The Biggest Tears Ever! | 7,200 | |
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| 39. | Isaac Run, But Every Item Is A Golden Horse Pill... | 7,114 | | The Binding of Isaac: Rebirth
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| 40. | New Final Boss And New Ending! Unlocking Secret Character In Isaac! | 7,045 | | The Binding of Isaac: Rebirth
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| 41. | Playable Peter Griffin In Fiend Folio! Impossible To Win! | 6,607 | | The Binding of Isaac: Rebirth
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| 42. | This New Damocles Sword Is Extremely Risky... | 6,248 | | Damocles
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| 43. | This New Spoon Bender Brings Homing To The Next Level! | 6,096 | |
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| 44. | They Turned Crane Game Into A Character! It's BROKEN! | 5,978 | |
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| 45. | This New Alternative Floor Changed EVERYTHING! | 5,835 | | The Binding of Isaac: Rebirth
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| 46. | This Tainted Damocles Can One Shot Enemies! | 5,824 | | The Binding of Isaac: Rebirth
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| 47. | This New Tarnished Isaac Birthright Literally Breaks Your Run! | 5,758 | | The Binding of Isaac: Rebirth
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| 48. | This New Technology Gives You The Biggest Laser Shot EVER! | 5,584 | |
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| 49. | This Is Why Tarnished Maggy Is Too Overpowered! The Deadliest Cardiac Arrest Ever! | 5,474 | | The Binding of Isaac: Rebirth
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| 50. | This New Character Has The CRAZIEST Synergies! | 5,453 | | The Binding of Isaac: Rebirth
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| 51. | They Added A New Beggar To The Game! He's Hilarious! | 5,445 | |
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| 52. | They Added Playable Donation Machine To The Game! It Was A Mistake. | 5,428 | |
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| 53. | I Just Unlocked Tarnished Lost And It's INSANE! | 5,415 | | The Binding of Isaac: Rebirth
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| 54. | I Didn't Want To Rig This Run, But... Fiend Folio Challenge #8 | 5,174 | | The Binding of Isaac: Rebirth
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| 55. | Spindown Dice & Brimstone Start? Golem Gets A Free Win! | 5,082 | | The Binding of Isaac: Rebirth
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| 56. | They Turned The Entire Solar System Into A Character! It's INSANE! | 5,035 | |
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| 57. | Playing New Pure Isaac Is Extremely Fun! | 5,017 | | The Binding of Isaac: Rebirth
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| 58. | Pure Maggy Is Extremely Cute! | 5,001 | |
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| 59. | This New Golden Mushroom Gives INSANE Stats! | 4,932 | | The Binding of Isaac: Rebirth
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| 60. | How Did I Get Both Regular And Tainted Items? Custom Challenge Gone Wrong | 4,910 | | The Binding of Isaac: Rebirth
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| 61. | I Found The Most Broken Lost EVER! | 4,903 | | The Binding of Isaac: Rebirth
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| 62. | The Secret Character From Godmode Achieved! The Sign Gameplay! | 4,815 | |
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| 63. | They Made A Challenge For Tarnished Lost?! Epiphany Challenge #9 | 4,784 | | The Binding of Isaac: Rebirth
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| 64. | This New Playable Dead Isaac Is Insane! | 4,718 | | The Binding of Isaac: Rebirth
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| 65. | New Reworked Tarnished Judas Is INSANE! | 4,706 | |
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| 66. | The Greediest Character Ever Made! Tarnished Keeper Gameplay! | 4,616 | | The Binding of Isaac: Rebirth
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| 67. | What Can 3000+ Hours Isaac Player Do On The First Floor? | 4,613 | | The Binding of Isaac: Rebirth
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| 68. | The Bloodiest Character In The Game! Tarnished Maggy Gameplay! | 4,569 | | The Binding of Isaac: Rebirth
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| 69. | Tarnished Judas Unlock! The Best Golden Brimstone Synergy Ever! | 4,560 | | The Binding of Isaac: Rebirth
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| 70. | They Added New Devil Sacred Heart?! It's INSANE! | 4,540 | |
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| 71. | What Happens If Forgotten Gets 27 Bones!? | 4,521 | | The Binding of Isaac: Rebirth
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| 72. | This New Character Is Too Explosive... Nadab Gameplay! | 4,507 | | The Binding of Isaac: Rebirth
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| 73. | New Upgraded Mutant Spider Is Extremely Powerful! | 4,470 | |
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| 74. | The Painful Truth About Tarnished Lost... | 4,469 | |
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| 75. | This New Tainted Character Is Extremely Hard... | 4,463 | |
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| 76. | This Guy Is Too Overpowered! Trying Tarnished Isaac For The First Time! | 4,404 | | The Binding of Isaac: Rebirth
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| 77. | What Happens If Forgotten Gets Too Many Damage Multipliers? | 4,337 | | The Binding of Isaac: Rebirth
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| 78. | Can I Survive Without Taking Items?! Insane Tainted Apollyon Custom Challenge! | 4,294 | | The Binding of Isaac: Rebirth
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| 79. | Getting All The Completion Marks As Fiend In One Run?! | 4,272 | | The Binding of Isaac: Rebirth
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| 80. | They Added Tanks To Isaac?! Commander Challenge! | 4,263 | | The Binding of Isaac: Rebirth
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| 81. | This New Item Almost Crashed My Game! | 4,257 | |
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| 82. | Getting Better Items As Tainted Lost! (For Real This Time) | 4,251 | | The Binding of Isaac: Rebirth
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| 83. | This New Character Has Craziest Items! Researcher Gameplay! | 4,227 | |
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| 84. | The Greediest Run You Have Ever Seen! Tarnished Keeper VS Greedier! | 4,219 | | The Binding of Isaac: Rebirth
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| 85. | They Made A Harder Tainted Forgotten Version? Abihu Gameplay! | 4,143 | | The Binding of Isaac: Rebirth
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| 86. | Isaac, But Every Enemy Is Also Isaac | 4,140 | | The Binding of Isaac: Rebirth
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| 87. | Alcoholic Catgirl Is Ridiculously Drunk! | 4,125 | |
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| 88. | This New Secret Miniboss Is Too Horrifying! | 4,117 | |
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| 89. | Trying Tarnished Judas For The First Time! Amazing Tainted Knife Synergy! | 4,112 | | The Binding of Isaac: Rebirth
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| 90. | This New Samael's Weapon Has The Craziest Synergies! | 4,086 | |
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| 91. | Can I Survive With 50 Enemies In The Room?! Fiend Folio challenge #7 | 4,055 | | The Binding of Isaac: Rebirth
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| 92. | Playable Fortune Telling Machine Is Hilarious! | 4,055 | |
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| 93. | This New Item Gives You Super Homing Tears! | 4,036 | |
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| 94. | Adding This Sawblade To Isaac Was A Mistake... | 4,017 | | The Binding of Isaac: Rebirth
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| 95. | Another Tarnished Character Is Here! How To Unlock Tarnished Maggy? | 4,014 | Guide | The Binding of Isaac: Rebirth
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| 96. | These Hands Won't Let Me Go! Fiend Folio Bonus Challenge! | 3,981 | | The Binding of Isaac: Rebirth
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| 97. | How Can I Survive This?! Insane Bomb Custom Challenge! | 3,953 | | The Binding of Isaac: Rebirth
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| 98. | Double Death Certificate On The First Floor! The Luckiest Azazel Run In The World! | 3,930 | | The Binding of Isaac: Rebirth
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| 99. | This New Character Has Insane Sword Synergies! | 3,929 | |
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| 100. | The Most Expensive Deal I've Ever Done! 50+ Hearts Damocles! | 3,875 | | The Binding of Isaac: Rebirth
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