| 1. |  Upper Echelon | Industrialized Medical Fraud - Big Pharma and a Perverse Government | 880 | |
| 2. |  Sips | Big Pharma (PC - First Look/Gameplay) - An Evening With Sips | 724 | First Impressions |
| 3. |  perpetuumworld | Симулятор производства таблеток ! ( Big Pharma ) | 573 | |
| 4. |  STAMSITE | Testar Big Pharma! (Swedish) | 470 | |
| 5. |  Azehara Ch | Pippa on Big Pharma | 344 | |
| 6. | perpetuumworld | Изобретаем новые лекарства ! ( Big Pharma ) | 334 | |
| 7. | quill18 | Let's Make Drugs: Big Pharma #4 | 304 | |
| 8. | quill18 | Let's Make Drugs: Big Pharma #1 | 264 | |
| 9. | EnterElysium | Big Pharma Needs You #01 [Acne] - Let's Play | 248 | Let's Play |
| 10. | Northernlion | Let's Look At: Big Pharma! | 243 | |
| 11. |  Sterakdary | Big Pharma - Jak na jedničku z chemie! [CZ / Česky] | 218 | |
| 12. |  Samed Güngör | İlk İzlenim : Big Pharma | 210 | |
| 13. | Generikb | "#1 DRUG MAKER IN THE WORLD!!!" - Big Pharma Part 04 - 1080p HD PC Gameplay Walkthrough | 208 | Walkthrough |
| 14. |  CRYSTAL | СОЗДАЙ СВОЮ МЕДИЦИНУ! | 205 | |
| 15. | Generikb | "HERMITECH™ MAKING DRUGS!!!" - Big Pharma Part 01 - 1080p HD PC Gameplay Walkthrough | 201 | Walkthrough |
| 16. | Valuetainment | “They Control Content” - How Big Pharma Controls Mainstream Media | 198 | |
| 17. | Moist Charlie Clips | Mark Cuban's Company That's Undercutting Big Pharma | MoistCr1tikal | 198 | |
| 18. | EnterElysium | Big Pharma Needs You #07 [Malaria] - Let's Play | 176 | Let's Play |
| 19. | Worth A Buy | Big Pharma Review - Worth a Buy? | 169 | Review |
| 20. | Aavak | Big Pharma 1 *First Taste* - Misery Money | 156 | |
| 21. | CRYSTAL | ЗАРАБАТЫВАЕМ МИЛЛИОН ЛЕКАРСТВАМИ! - Big Pharma | 154 | |
| 22. | EnterElysium | Big Pharma Needs You #02 [Female Contraceptive] - Let's Play | 143 | Let's Play |
| 23. | quill18 | Let's Make Drugs: Big Pharma #2 | 141 | |
| 24. | EnterElysium | Big Pharma Needs You #04 [Bipolar] - Let's Play | 139 | Let's Play |
| 25. | EnterElysium | Big Pharma Needs You #03 [Erectile Disfunction] - Let's Play | 128 | Let's Play |
| 26. |  Debitor | Ich stelle ab jetzt Drogen her | 127 | |
| 27. | CRYSTAL | ЗАРАБОТАЙ ДЕНЬГИ НА ЛЕКАРСТВАХ! | 123 | |
| 28. | EnterElysium | Big Pharma Needs You #05 [Insomnia] - Let's Play | 122 | Let's Play |
| 29. | EnterElysium | Big Pharma [Evil Drugs Company Sim] - Beta Impressions | 119 | |
| 30. | Generikb | "DRUGS...SHAKEN NOT STIRRED!!!" - Big Pharma Part 03 - 1080p HD PC Gameplay Walkthrough | 109 | Walkthrough |
| 31. | STAMSITE | Dags för nya mediciner! - Big Pharma #2! (Swedish) | 106 | |
| 32. | CRYSTAL | СОЗДАЁМ СВОИ ЛЕКАРСТВА! - Big Pharma | 105 | |
| 33. | Skye Storme | Big Pharma Part 1 ►The Basics for Success!◀ Tutorial/Beta Gameplay | 104 | Tutorial |
| 34. | quill18 | Let's Make Drugs: Big Pharma #3 | 102 | |
| 35. | Generikb | "GET OUT GOUT!!!" - Big Pharma Part 02 - 1080p HD PC Gameplay Walkthrough | 98 | Walkthrough |
| 36. | EnterElysium | Big Pharma Marketing and Malpractice #01 I AM MARTIN SHKRELI - Let's Play | 93 | Let's Play |
| 37. | CRYSTAL | ЛЕКАРСТВА ЭТО БИЗНЕС! | 93 | |
| 38. | docm77 | HOW TO MAKE DRUGS - Big Pharma Gameplay E01 | Docm77 | 92 | Guide |
| 39. | Channeling Erik | Big Pharma and Alcoholism | 92 | |
| 40. | STAMSITE | Dags att färga fabriken! - Big Pharma #6! (Swedish) | 88 | |
| 41. | Aavak | Big Pharma 2 *First Taste* - Max Strength | 87 | |
| 42. | STAMSITE | Fem level tvåor?! - Big Pharma #7! (Swedish) | 87 | |
| 43. | Generikb | "I'VE LOST MY APPETITE!!!" - Big Pharma Part 05 - 1080p HD PC Gameplay Walkthrough | 85 | Walkthrough |
| 44. | Gadarol | Big Pharma #1 EINFACH GEIL! Erste Schritte Der Pillen Fabrik Simulator BETA Gameplay deutsch | 85 | |
| 45. | STAMSITE | Mängder med småsaker! - Big Pharma #5! (Swedish) | 84 | |
| 46. | Yippee Ki Yay Mr Falcon | Let's Play Big Pharma - Dick Fungal Wart Punisher - Part 1 [Big Pharma Gameplay] | 80 | Let's Play |
| 47. | EnterElysium | Big Pharma Needs You #06 [Liver Disease] - Let's Play | 78 | Let's Play |
| 48. | Aavak | Big Pharma 3 *First Taste* - Keep Calm and Drink Tea! | 78 | |
| 49. |  MetalBear | Big Pharma #01 "Medicamento Manipulado" - Gameplay Português Vamos Jogar PT-BR | 77 | |
| 50. | STAMSITE | Monstermaskin! - Big Pharma #4! (Swedish) | 75 | |
| 51. | Aavak | Big Pharma 4 *First Taste* - Back in the Black | 72 | |
| 52. | MaxPalaro | Jogando Big Pharma com Max #1 | 65 | Let's Play |
| 53. | CRYSTAL | СОЗДАЕМ НОВЫЕ ЛЕКАРСТВА! - Big Pharma | 64 | |
| 54. | Yippee Ki Yay Mr Falcon | Big Pharma Update! - Dick Stomach Pain Zapper ADHD Reducer - Let's Play - Ep 6 | 64 | Let's Play |
| 55. | EnterElysium | Big Pharma #04 [Irritable Bowel Syndrome] Megacure - Let's Play | 63 | Let's Play |
| 56. | EnterElysium | Big Pharma Marketing and Malpractice #02 - Let's Play | 62 | Let's Play |
| 57. | Pravus | Steamed! | Big Pharma | 61 | |
| 58. | EnterElysium | Big Pharma Marketing and Malpractice #08 - Let's Play | 58 | Let's Play |
| 59. | VoodyGames | СИМУЛЯТОР ФАРМАЦЕВТА! | 57 | |
| 60. | EnterElysium | Big Pharma Marketing and Malpractice #03 - Let's Play | 57 | Let's Play |
| 61. | Yippee Ki Yay Mr Falcon | Big Pharma Gameplay - Dick Preg Buster - Let's Play - Part 3 | 55 | Let's Play |
| 62. | Biffa Plays Indie Games | Big Pharma Game First Look Gameplay (1080p/60) | 55 | First Impressions |
| 63. | tom.io | Checkliste: Big Pharma (beta) [ Deutsch / German ] | 54 | |
| 64. | ZigTheHedge | [Запись стрима] Big Pharma - Зиг - варить! | 53 | |
| 65. | EnterElysium | Big Pharma Marketing and Malpractice #09 - Let's Play | 50 | Let's Play |
| 66. | Первый Хоррор Канал | Big Pharma Прохождение На Русском — СИМУЛЯТОР ПРОИЗВОДСТВА ЛЕКАРСТВ | 49 | |
| 67. | Skye Storme | Big Pharma Part 3 ►A Game of Margins (1 of 3)◀ Tutorial/Beta Gameplay | 48 | Tutorial |
| 68. | EnterElysium | Big Pharma #03 [Appetite Suppressant] Megacure - Let's Play | 47 | Let's Play |
| 69. | EnterElysium | Big Pharma Marketing and Malpractice #07 - Let's Play | 46 | Let's Play |
| 70. | STAMSITE | Låt Penny tjäna en penny! - Big Pharma #3! (Swedish) | 46 | |
| 71. | EnterElysium | Big Pharma #01 [Hyperthyroidism] Cornering the Low End - Let's Play | 42 | Let's Play |
| 72. | Skye Storme | Big Pharma Part 2 ►Upgrade Drugs for Big Cash!◀ Tutorial/Beta Gameplay | 41 | Tutorial |
| 73. | EnterElysium | Big Pharma #08 [Male Contraceptive] Money Spinners - Let's Play | 41 | Let's Play |
| 74. | EnterElysium | Big Pharma #01 [Insomnia] Megacure - Let's Play | 41 | Let's Play |
| 75. | EnterElysium | Big Pharma Marketing and Malpractice #04 - Let's Play | 40 | Let's Play |
| 76. | PhoenixRZN | Big Pharma. Прохождение с Русским Комментатором (видео 1) | 39 | |
| 77. | Stuff+ | Beverage + Big Pharma #1 [Beta] | 39 | Let's Play |
| 78. |  Nathan's Sandbox | Big Pharma: Ep. #1 - SELLING DRUGS -= Gameplay & Walkthrough =- | 39 | Walkthrough |
| 79. | Skye Storme | Big Pharma Part 8 ►Show Me The Money (3 of 3)◀ Tutorial/Beta Gameplay | 38 | Tutorial |
| 80. | EnterElysium | Big Pharma #02 [Asthma] Megacure - Let's Play | 38 | Let's Play |
| 81. | Stuff+ | Preview + Big Pharma [Beta] | 37 | Let's Play |
| 82. |  MisterDaweed | Big Pharma - Découverte | 37 | |
| 83. | docm77 | LOSING WEIGHT WITH DRUGS - Big Pharma Gameplay E02 | Docm77 | 35 | |
| 84. | Yippee Ki Yay Mr Falcon | Big Pharma - Dick Diabeto Buddy! - Gameplay - Let's Play Episode 2 | 35 | Let's Play |
| 85. | EnterElysium | Big Pharma Marketing and Malpractice #06 - Let's Play | 35 | Let's Play |
| 86. |  Deluks Gaming | Big Pharma ► Episode 01 ► Gameplay Tutorial - Intermediate Mastery Series! | 34 | Show |
| 87. | Dudey Rhino | Big Pharma Billionaire Murdered! The Killer is Still Out There... | 33 | |
| 88. | Ben ~ Frizzlenpop | BUILDING MY OWN PILL FACTORY?! - *TYCOON TUESDAY* BIG PHARMA | 33 | |
| 89. | MetalBear | Big Pharma #04 "A gripe não coopera" - Gameplay Português Vamos Jogar PT-BR | 33 | |
| 90. | Skye Storme | Big Pharma Part 6 ►Show Me The Money (1 of 3)◀ Tutorial/Beta Gameplay | 33 | Tutorial |
| 91. | EnterElysium | Big Pharma Marketing and Malpractice #05 - Let's Play | 33 | Let's Play |
| 92. | docm77 | ADVANCED DRUGS & MIXER TUTORIAL - Big Pharma Gameplay E03 | Docm77 | 32 | Tutorial |
| 93. | Skye Storme | Big Pharma Part 4 ►A Game of Margins (2 of 3)◀ Tutorial/Beta Gameplay | 31 | Tutorial |
| 94. | EnterElysium | Big Pharma #02 [Asthma] Money Spinners - Let's Play | 30 | Let's Play |
| 95. | Skye Storme | Big Pharma Part 7 ►Show Me The Money (2 of 3)◀ Tutorial/Beta Gameplay | 30 | Tutorial |
| 96. | WeaselZone | Big Pharma - HOW TO MAKE DRUGS - Overview & Tutorial ★ Let's Play Big Pharma | 30 | Tutorial |
| 97. | MaxPalaro | AINDA MAIS RICO!! | Big Pharma #6 | 29 | |
| 98. | tom.io | Big Pharma - Intermediate - Level 1 - Folge 2 [ Deutsch / German / Let´s Play ] | 29 | |
| 99. | Yippee Ki Yay Mr Falcon | Big Pharma Gameplay - Dick Vomit-No-More - Let's Play - Part 5 | 29 | Let's Play |
| 100. | Skye Storme | Big Pharma Part 5 ►A Game of Margins (3 of 3)◀ Tutorial/Beta Gameplay | 29 | Tutorial |
