| Ouroboros: Prelude (2017) | 1,227 | 4 |
| ourWorld (2007) | 501,943 | 32 |
| Out and About (2025) | 55,964 | 23 |
| Out Board (1990) | 1,173,359 | 24 |
| Out Live (1989) | 809,927 | 171 |
| Out of Gas (1992) | 2,782,133 | 207 |
| Out of Hand: Deluxe (2025) | 9 | 1 |
| Out of Line (2021) | 2,410,211 | 1,265 |
| Out of Nowhere (2024) | 12,503,174 | 832 |
| Out of Ore (2022) | 4,470,444 | 1,920 |
| Out of Reach (2015) | 5,879,202 | 784 |
| Out of Reach: Treasure Royale (2020) | 468,303 | 155 |
| Out of Sight (2021) | 4,029,418 | 1,184 |
| Out of Space (2019) | 19,408,284 | 1,453 |
| Out of the Box (2018) | 11,521,220 | 290 |
| Out of the Park Baseball (1999) | 1,136,748 | 3,433 |
| Out of the Park Baseball 10 (2009) | 0 | 0 |
| Out of the Park Baseball 11 (2010) | 33,829 | 1 |
| Out of the Park Baseball 12 (2011) | 17,208 | 3 |
| Out of the Park Baseball 13 (2012) | 35,625 | 10 |
| Out of the Park Baseball 14 (2013) | 21,544 | 7 |
| Out of the Park Baseball 15 (2014) | 354,447 | 129 |
| Out of the Park Baseball 16 (2015) | 445,617 | 177 |
| Out of the Park Baseball 17 (2016) | 381,288 | 356 |
| Out of the Park Baseball 18 (2017) | 597,934 | 809 |
| Out of the Park Baseball 19 (2018) | 839,818 | 597 |
| Out of the Park Baseball 2 (2000) | 15 | 1 |
| Out of the Park Baseball 20 (2019) | 1,062,346 | 443 |
| Out of the Park Baseball 21 (2020) | 1,347,294 | 1,792 |
| Out of the Park Baseball 22 (2021) | 1,846,832 | 1,785 |
| Out of the Park Baseball 3 (2001) | 0 | 0 |
| Out of the Park Baseball 4 (2002) | 0 | 0 |
| Out of the Park Baseball 5 (2003) | 0 | 0 |
| Out of the Park Baseball 6 (2004) | 23 | 1 |
| Out of the Park Baseball 6.5 (2005) | 0 | 0 |
| Out of the Park Baseball 8 (2007) | 137 | 1 |
| Out of the Park Baseball 9 (2008) | 0 | 0 |
| Out of the Park Baseball Manager 2006 (2006) | 0 | 0 |
| Out of the Shadows (1984) | 5,843,203 | 600 |
| Out of Your Mind (2024) | 393,243 | 17 |
| Out Run (1986) | 13,636,699 | 4,794 |
| Out Run Europa (1991) | 241,980 | 230 |
| Out There (2014) | 226,576,500 | 2,593 |
| Out There Somewhere (2012) | 1,503,977 | 558 |
| Out There: Oceans of Time (2021) | 1,006,807 | 270 |
| Out to Lunch (1993) | 832,955 | 206 |
| Out Zone (1990) | 420,356 | 363 |
| The Outbound Ghost (2022) | 1,010,081 | 1,217 |
| Outbreak (2017) | 102,406,393 | 5,016 |
| Outbreak Island: Pendulum (2022) | 1,616,904 | 560 |
| Outbreak Overlord (2024) | 366 | 4 |
| Outbreak The Fedora Files: What Lydia Knows (2024) | 244 | 1 |
| Outbreak: Contagious Memories (2022) | 150,916 | 170 |
| Outbreak: Endless Nightmares (2021) | 404,343 | 320 |
| Outbreak: Epidemic (2020) | 198,597 | 213 |
| Outbreak: Lost Hope (2019) | 86,504 | 138 |
| Outbreak: Shades of Horror Chromatic Split (2024) | 107,172 | 54 |
| Outbreak: The New Nightmare (2018) | 853,114 | 299 |
| Outbreak: The Nightmare Chronicles (2018) | 142,031 | 218 |
| Outbuddies (2019) | 213,945 | 167 |
| OUTBUDDIES DX (2019) | 51,321 | 154 |
| Outcast (1999) | 3,834,106 | 1,185 |
| Outcast - A New Beginning (2024) | 5,922,817 | 4,813 |
| Outcast 1.1 (2014) | 433,710 | 380 |
| The Outcast Lovers (2020) | 1,552 | 27 |
| Outcast Tales: The First Journey (2024) | 33,973 | 72 |
| Outcast: Second Contact (2017) | 2,867,373 | 1,985 |
| Outcasters (2020) | 1,566,741 | 554 |
| Outcore: Desktop Adventure (2022) | 13,472,163 | 822 |
| Outcry (2008) | 666,443 | 210 |
| Outdoor Adventures With Marisa Kirisame (2022) | 4,874 | 13 |
| Outdoors Unleashed: Africa 3D (2011) | 9,766 | 3 |
| OutDrive (2016) | 554,862 | 121 |
| The Outer Space Bugs (2022) | 215 | 2 |
| Outer Space Shack (2023) | 9,836 | 10 |
