| Z (1996) | 7,106,014 | 1,146 |
| Z Ops: DeadZone (2025) | 0 | 0 |
| Z-Factor (2025) | 0 | 0 |
| Z-Out (1990) | 176,506 | 77 |
| Z-Tack (1983) | 1,422 | 18 |
| Z.H.P. Unlosing Ranger VS Darkdeath Evilman (2010) | 366,036 | 351 |
| Z.I.O.N. (2016) | 9,733,247 | 1,603 |
| Z.O.N.A: Origin (2024) | 156,582 | 139 |
| Z/X Code OverBoost (2019) | 28,365 | 51 |
| Z1 Battle Royale (2015) | 523,364,546 | 101,296 |
| Z3TA+ 2 (2013) | 0 | 0 |
| Z: Escape (2018) | 2,564,611 | 359 |
| Z: Steel Soldiers (2001) | 200,828 | 139 |
| ZAAM (2020) | 1,047,260 | 84 |
| Zaba The Frog (2017) | 0 | 0 |
| ZaBaTa! (2023) | 59,594 | 11 |
| Zabawa Karaoke (2022) | 0 | 0 |
| Zac Zac adventure (2020) | 0 | 0 |
| Zaccaria Pinball (2013) | 692,395 | 2,380 |
| ZaciSa: Defense of the Crayon Dimension! (2023) | 1,647 | 17 |
| Zack 2: Celestine's Map (2021) | 47,586 | 15 |
| Zack Y (2018) | 0 | 0 |
| Zack Zero (2012) | 749,849 | 301 |
| Zafehouse Diaries (2012) | 1,062,977 | 572 |
| Zafehouse Diaries 2 (2017) | 113,200 | 92 |
| Zahalia: The Knights of Galiveth (2017) | 1 | 1 |
| Zak McKracken and the Alien Mindbenders (1988) | 1,289,327 | 1,150 |
| Zak McKracken: Between Time and Space (2008) | 120,921 | 287 |
| Zakk Hazard The Deadly Spawn (2019) | 143 | 2 |
| Zako Slayer (2022) | 19 | 1 |
| Zaku (2009) | 1,752,743 | 243 |
| Zakuro no Aji (1995) | 12,190 | 17 |
| ZAMB! Redux (2018) | 2,075 | 9 |
| Zampabolas (1989) | 579 | 8 |
| Zan II: Spirits (1992) | 10,284 | 28 |
| Zan III: Ten'un Ware ni Ari (1993) | 4,790 | 10 |
| Zan: Yasha Enbukyoku (1990) | 1,826,035 | 201 |
| Zanac (1986) | 1,185,206 | 935 |
| Zanac AI (2007) | 4,192 | 6 |
| Zangband (1994) | 17,796 | 24 |
| Zangeki no Reginleiv (2010) | 919,195 | 542 |
| Zanki Zero: Last Beginning (2018) | 4,036,758 | 4,746 |
| Zany Golf (1988) | 737,279 | 181 |
| ZanZarah: The Hidden Portal (2002) | 1,248,122 | 1,694 |
| Zap! (2005) | 163,404,988 | 1,307 |
| Zap! Snowboarding Trix (1997) | 17,969 | 37 |
| Zapactris (2002) | 70 | 2 |
| Zapitalism (1997) | 4,622 | 17 |
| Zapling Bygone (2022) | 112,250 | 226 |
| Zapper: One Wicked Cricket (2002) | 937,978 | 377 |
| ZAR (1998) | 353,668 | 68 |
| Zaraq (2025) | 0 | 0 |
| Zarathrusta (1991) | 739 | 3 |
| Zarathustra - Cybergeddon (2024) | 2,990 | 16 |
| Zarch (1987) | 56,549 | 47 |
| Zardon (1982) | 153 | 2 |
| Zardy's Maze (2021) | 10,209,173 | 725 |
| Zarlor Mercenary (1990) | 20,758 | 49 |
| Zarya and the Cursed Skull (2017) | 22,012 | 38 |
| Zarya-1: Mystery on the Moon (2017) | 0 | 0 |
| Zarzon (1981) | 36,623 | 28 |
| Zatch Bell! Electric Arena (2005) | 216,533 | 292 |
| Zatch Bell! Mamodo Battles (2005) | 2,182,258 | 846 |
| Zatch Bell! Mamodo Fury (2004) | 3,441,813 | 753 |
| Zathura: A Space Adventure (2005) | 6,548,724 | 343 |
| Zatorski, Ph.D. (2020) | 461 | 2 |
| Zavix Tower (2016) | 12,810 | 26 |
| ZAVOD (2022) | 1,829,234 | 66 |
| Zax: The Alien Hunter (2001) | 81,795 | 152 |
| Zaxterion: Space Frenzy! (2022) | 855 | 13 |
| Zaxxon (1982) | 1,096,101 | 586 |
| Zaxxon 3D (1987) | 102,573 | 96 |
| Zaxxon's Motherbase 2000 (1995) | 156,753 | 120 |
| ZCREW (2022) | 35,759 | 38 |
| Zebco Fishing! (1999) | 18,457 | 187 |
