| Z (1996) | 7,105,856 | 1,147 |
| Z Ops: DeadZone (2025) | 0 | 0 |
| Z-Factor (2025) | 0 | 0 |
| Z-Out (1990) | 176,496 | 76 |
| Z-Tack (1983) | 1,422 | 18 |
| Z.H.P. Unlosing Ranger VS Darkdeath Evilman (2010) | 365,672 | 350 |
| Z.I.O.N. (2016) | 9,706,287 | 1,589 |
| Z.O.N.A: Origin (2024) | 156,033 | 137 |
| Z/X Code OverBoost (2019) | 28,365 | 51 |
| Z1 Battle Royale (2015) | 523,789,366 | 101,465 |
| Z3TA+ 2 (2013) | 0 | 0 |
| Z: Escape (2018) | 2,564,565 | 359 |
| Z: Steel Soldiers (2001) | 200,506 | 138 |
| ZAAM (2020) | 1,047,260 | 84 |
| Zaba The Frog (2017) | 0 | 0 |
| ZaBaTa! (2023) | 59,594 | 11 |
| Zabawa Karaoke (2022) | 0 | 0 |
| Zac Zac adventure (2020) | 0 | 0 |
| Zaccaria Pinball (2013) | 670,267 | 2,286 |
| ZaciSa: Defense of the Crayon Dimension! (2023) | 1,647 | 17 |
| Zack 2: Celestine's Map (2021) | 47,586 | 15 |
| Zack Y (2018) | 0 | 0 |
| Zack Zero (2012) | 749,765 | 299 |
| Zafehouse Diaries (2012) | 1,062,010 | 572 |
| Zafehouse Diaries 2 (2017) | 113,178 | 91 |
| Zahalia: The Knights of Galiveth (2017) | 1 | 1 |
| Zak McKracken and the Alien Mindbenders (1988) | 1,270,698 | 1,123 |
| Zak McKracken: Between Time and Space (2008) | 120,734 | 275 |
| Zakk Hazard The Deadly Spawn (2019) | 143 | 2 |
| Zako Slayer (2022) | 19 | 1 |
| Zaku (2009) | 1,726,958 | 233 |
| Zakuro no Aji (1995) | 12,190 | 17 |
| ZAMB! Redux (2018) | 2,075 | 9 |
| Zampabolas (1989) | 579 | 8 |
| Zan II: Spirits (1992) | 10,276 | 26 |
| Zan III: Ten'un Ware ni Ari (1993) | 4,790 | 10 |
| Zan: Yasha Enbukyoku (1990) | 1,825,875 | 198 |
| Zanac (1986) | 1,177,043 | 931 |
| Zanac AI (2007) | 4,192 | 6 |
| Zangband (1994) | 17,780 | 24 |
| Zangeki no Reginleiv (2010) | 919,140 | 542 |
| Zanki Zero: Last Beginning (2018) | 4,030,193 | 4,745 |
| Zany Golf (1988) | 734,548 | 176 |
| ZanZarah: The Hidden Portal (2002) | 1,228,020 | 1,647 |
| Zap! (2005) | 163,347,721 | 1,281 |
| Zap! Snowboarding Trix (1997) | 15,614 | 33 |
| Zapactris (2002) | 70 | 2 |
| Zapitalism (1997) | 4,622 | 17 |
| Zapling Bygone (2022) | 112,250 | 226 |
| Zapper: One Wicked Cricket (2002) | 937,107 | 372 |
| ZAR (1998) | 349,876 | 65 |
| Zaraq (2025) | 0 | 0 |
| Zarathrusta (1991) | 739 | 3 |
| Zarathustra - Cybergeddon (2024) | 2,990 | 16 |
| Zarch (1987) | 56,549 | 47 |
| Zardon (1982) | 153 | 2 |
| Zardy's Maze (2021) | 10,208,577 | 723 |
| Zarlor Mercenary (1990) | 20,734 | 48 |
| Zarya and the Cursed Skull (2017) | 22,012 | 38 |
| Zarya-1: Mystery on the Moon (2017) | 0 | 0 |
| Zarzon (1981) | 36,623 | 28 |
| Zatch Bell! Electric Arena (2005) | 215,530 | 282 |
| Zatch Bell! Mamodo Battles (2005) | 2,181,275 | 823 |
| Zatch Bell! Mamodo Fury (2004) | 3,437,193 | 733 |
| Zathura: A Space Adventure (2005) | 6,504,957 | 333 |
| Zatorski, Ph.D. (2020) | 461 | 2 |
| Zavix Tower (2016) | 12,810 | 26 |
| ZAVOD (2022) | 1,829,144 | 62 |
| Zax: The Alien Hunter (2001) | 81,788 | 152 |
| Zaxterion: Space Frenzy! (2022) | 855 | 13 |
| Zaxxon (1982) | 1,095,303 | 584 |
| Zaxxon 3D (1987) | 102,338 | 96 |
| Zaxxon's Motherbase 2000 (1995) | 156,070 | 119 |
| ZCREW (2022) | 35,751 | 38 |
| Zebco Fishing! (1999) | 18,430 | 186 |
