| Z (1996) | 7,105,958 | 1,146 |
| Z Ops: DeadZone (2025) | 0 | 0 |
| Z-Factor (2025) | 0 | 0 |
| Z-Out (1990) | 176,496 | 76 |
| Z-Tack (1983) | 1,422 | 18 |
| Z.H.P. Unlosing Ranger VS Darkdeath Evilman (2010) | 366,034 | 351 |
| Z.I.O.N. (2016) | 9,726,702 | 1,595 |
| Z.O.N.A: Origin (2024) | 156,582 | 139 |
| Z/X Code OverBoost (2019) | 28,365 | 51 |
| Z1 Battle Royale (2015) | 523,354,527 | 101,323 |
| Z3TA+ 2 (2013) | 0 | 0 |
| Z: Escape (2018) | 2,564,586 | 359 |
| Z: Steel Soldiers (2001) | 200,747 | 139 |
| ZAAM (2020) | 1,047,260 | 84 |
| Zaba The Frog (2017) | 0 | 0 |
| ZaBaTa! (2023) | 59,594 | 11 |
| Zabawa Karaoke (2022) | 0 | 0 |
| Zac Zac adventure (2020) | 0 | 0 |
| Zaccaria Pinball (2013) | 690,020 | 2,361 |
| ZaciSa: Defense of the Crayon Dimension! (2023) | 1,647 | 17 |
| Zack 2: Celestine's Map (2021) | 47,586 | 15 |
| Zack Y (2018) | 0 | 0 |
| Zack Zero (2012) | 749,829 | 301 |
| Zafehouse Diaries (2012) | 1,062,605 | 572 |
| Zafehouse Diaries 2 (2017) | 113,200 | 92 |
| Zahalia: The Knights of Galiveth (2017) | 1 | 1 |
| Zak McKracken and the Alien Mindbenders (1988) | 1,271,944 | 1,136 |
| Zak McKracken: Between Time and Space (2008) | 120,823 | 275 |
| Zakk Hazard The Deadly Spawn (2019) | 143 | 2 |
| Zako Slayer (2022) | 19 | 1 |
| Zaku (2009) | 1,744,412 | 236 |
| Zakuro no Aji (1995) | 12,190 | 17 |
| ZAMB! Redux (2018) | 2,075 | 9 |
| Zampabolas (1989) | 579 | 8 |
| Zan II: Spirits (1992) | 10,277 | 27 |
| Zan III: Ten'un Ware ni Ari (1993) | 4,790 | 10 |
| Zan: Yasha Enbukyoku (1990) | 1,825,957 | 199 |
| Zanac (1986) | 1,184,766 | 933 |
| Zanac AI (2007) | 4,192 | 6 |
| Zangband (1994) | 17,790 | 24 |
| Zangeki no Reginleiv (2010) | 919,187 | 542 |
| Zanki Zero: Last Beginning (2018) | 4,036,235 | 4,746 |
| Zany Golf (1988) | 734,654 | 178 |
| ZanZarah: The Hidden Portal (2002) | 1,242,343 | 1,670 |
| Zap! (2005) | 163,378,637 | 1,296 |
| Zap! Snowboarding Trix (1997) | 17,640 | 36 |
| Zapactris (2002) | 70 | 2 |
| Zapitalism (1997) | 4,622 | 17 |
| Zapling Bygone (2022) | 112,250 | 226 |
| Zapper: One Wicked Cricket (2002) | 937,690 | 376 |
| ZAR (1998) | 353,222 | 68 |
| Zaraq (2025) | 0 | 0 |
| Zarathrusta (1991) | 739 | 3 |
| Zarathustra - Cybergeddon (2024) | 2,990 | 16 |
| Zarch (1987) | 56,549 | 47 |
| Zardon (1982) | 153 | 2 |
| Zardy's Maze (2021) | 10,208,809 | 724 |
| Zarlor Mercenary (1990) | 20,758 | 49 |
| Zarya and the Cursed Skull (2017) | 22,012 | 38 |
| Zarya-1: Mystery on the Moon (2017) | 0 | 0 |
| Zarzon (1981) | 36,623 | 28 |
| Zatch Bell! Electric Arena (2005) | 216,128 | 291 |
| Zatch Bell! Mamodo Battles (2005) | 2,182,138 | 842 |
| Zatch Bell! Mamodo Fury (2004) | 3,441,359 | 751 |
| Zathura: A Space Adventure (2005) | 6,521,952 | 340 |
| Zatorski, Ph.D. (2020) | 461 | 2 |
| Zavix Tower (2016) | 12,810 | 26 |
| ZAVOD (2022) | 1,829,233 | 66 |
| Zax: The Alien Hunter (2001) | 81,788 | 152 |
| Zaxterion: Space Frenzy! (2022) | 855 | 13 |
| Zaxxon (1982) | 1,095,996 | 586 |
| Zaxxon 3D (1987) | 102,572 | 96 |
| Zaxxon's Motherbase 2000 (1995) | 156,753 | 120 |
| ZCREW (2022) | 35,759 | 38 |
| Zebco Fishing! (1999) | 18,456 | 187 |
