| 1. |  Forsen Plays | 21,226 | Forsen Plays High On Life - Part 2 (With Chat) | 3:03:51 |
| 2. | Kav The Gamer | 12,874 | High On Life Part 8 - 4K ᵁᴴᴰ 60ᶠᵖˢ RTX Ultra Settings #highonlife #rickandmorty #rtx4080 #xbox | 41:45 |
| 3. | Rocky Rockhead | 5,808 | We Did It! - HIGH ON LIFE | Blind Let's Play [ END ] | 23:25 |
| 4. | ForsenTV2 | 5,625 | Forsen Plays High On Life - Part 4 (With Chat) | 3:29:42 |
| 5. | UrAvgLuke | 5,281 | High on life - Wedidit, we finished the playthrough #shorts | 0:28 |
| 6. | Visual Walkthrough | 1,693 | High on Life Mission Get Help | 23:24 |
| 7. | Mithrie - Gaming News | 1,659 | High On Life DLC Release Date | 1:01 |
| 8. | ScottyDGaming | 1,108 | High On Life, Part 9 / Bounty Garmantuous, Last Boss, Ending, Secret Ending | 36:13 |
| 9. | Gaming Grandpa | 473 | 🔴LIVE🔴 Grandpa Plays High On LIfe - Part 8 - The End | 38:09 |
| 10. | LULZCREW | 377 | High on Life - Part 8 - Aidan Plays - The Finale - Embracing the Journey and Celebrating Adventure | 1:43:06 |
| 11. | Joxi_ | 374 | When you Help with Graffiti!?!??! High On Life #highonlife #gameplay | 0:54 |
| 12. | MattInTheHat | 316 | The Adventure Continues || High On Life - High On Knife DLC Playthrough Part 2 - End | 1:05:09 |
| 13. | mike247tanner | 300 | High on Life Part 9 - Nipulon, Garmantuous, and Jack Black!? ENDING | 32:59 |
| 14. | CND | 295 | HIGH ON LIFE (Garmantuous) Finale | 8:27 |
| 15. | TheOranguDan | 274 | YOU WON'T BELIEVE THIS!! | High On Life - Secret Ending! | 14:44 |
| 16. | Noveella | 266 | THIS game is HILARIOUS! 'High on Life' FULL play-through: PART 5! #gaming #live #highonlife #comedy | 2:12:31 |
| 17. | Beeb1up Gaming | 219 | High On Life Playthrough Part 13 (We're Going On A Trip, Babyyy!) | 26:11 |
| 18. | HatCHeTHaZ | 219 | HatCHeTHaZ Plays: High on Life: High on Knife - PS5 [Full Game] | 4:27:58 |
| 19. | Lazy Commander | 197 | "Let's Play" High On Life Part 13 - Bounty: Skrendel Bros | 37:44 |
| 20. | The Trans- Former Gamer | 183 | Lets Play High On Life #13 II The End II | 28:27 |
| 21. | SuperCrazyMark | 171 | High On Life - Super Crazy Playthrough - Part 12 - THE FINAL PART!!! | 26:50 |
| 22. | GrizzoUK | 163 | High on Life - Full Playthrough | 7:53:16 |
| 23. | TheCRCking | 133 | Big Chris Plays - High On Life - 09 - Garmantuous many holes | 54:26 |
| 24. | Shaun Thomas Gaming | 101 | High on Life Playthrough! | 20:56 |
| 25. | Benarti | 100 | FUNNY TALKING GUN and BOSS FIGHT! (High On Life lets play #1) | 22:06 |
| 26. | Denchi | 97 | HIGH ON LIFE - A 4K 60fps Playthrough of the new game! No Commentary Part 8 | 1:04:32 |
| 27. | Moose Lee | 88 | Moose Plays - HIGH ON LIFE PS5 (First playthrough) | 2:52:50 |
| 28. | InfInc TV | 81 | Con Plays High on Life - Episode 5 | 1:59:30 |
| 29. | The Polar Homestead Gaming | 78 | HIGH ON LIFE | Gameplay Playthrough | FHD 60FPS XBOX | No Commentary | Part 2 | | 1:46:54 |
| 30. | KreePeetZ | 75 | HIGH ON LIFE part 4 - I'M GODZILLA!!! | Let's Play | 35:35 |
| 31. | PcoAroGames | 74 | HIGH ON LIFE - Part 14 (ENDING) - Gaming Playthrough - XSX | 30:35 |
| 32. | MellowGamer 1999 | 67 | High on Life - [Episode-3] Full Let's Play | 1:34:54 |
| 33. | KalamityGaming | 66 | THE BEST WEAPON - High On Life Gameplay #1 | 23:48 |
| 34. | PilotPlaysGames | 64 | High On Life | Full Playthrough Day 2 | Twitch VOD | 4:00:31 |
| 35. | Bairdos | 55 | High on Life | It's Over! | Part 4 - Finale | 1:13:01 |
| 36. | Games, Brrraaains & A Head-Banging Life | 50 | Full Playthrough: High on Life - High on Knife DLC - All Achievements (No Commentary) | 5:35:20 |
| 37. | QuinntonTV | 48 | QUINNTONTV PLAYS... HIGH ON LIFE (This Game is Weird) | 43:46 |
| 38. | SaRa Game Room | 40 | High on Life Gameplay - Part 1 Prologue - Get Help [4K UHD 60fps] | 27:10 |
| 39. | JR900GAMING | 36 | Lets Buy A Bong. High On Life [JR900 Plays] Part 6 | 1:02:57 |
| 40. | STYPTICK | 34 | IVE UPGRADED|#5| High On Life Let's Play | 17:56 |
| 41. | Smudge329gaming | 34 | High On Life playthrough (Rick and Morty creator's ) EP.2 | 3:08:15 |
| 42. | 2Real Beats | 29 | Playthrough High on life (PART 1) Lets Destroy 9-Torg!!! | 52:11 |
| 43. | Centaur 616 Playthroughs | 29 | HIGH ON LIFE PLAYTHROUGH FINALE! | 1:26:17 |
| 44. | JUST GAMES | 27 | High On Life #02 | Let's Play | Twitch Stream | 2:02:55 |
| 45. | Kplayz23 | 27 | High on Life Playthrough - Part 3 | 46:16 |
| 46. | Andervaliant | 26 | HIGH ON LIFE PLAYTHROUGH TALKING GUNS COME ON GET IN HERE.(PART 1) | 54:11 |
| 47. | Super Saiyan Stokes | 25 | Owain Plays | High on Life | 1:38:14 |
| 48. | Mackay81 TV | 25 | From Ordinary to Extraordinary: The Funny High On Life | 2:32:56 |
| 49. | Dr Ravenholm | 23 | Taking Down the G3 - High On Life - Episode 6 | 3:30:34 |
| 50. | crypto gamer | 16 | let's play: High on life | 1:11:32 |
| 51. | HWAlphaWolf | 16 | High on Life play through ~ Part 1 | 49:05 |
| 52. | Gamebook Chronicles | 15 | [Live Let's play] High on Life | 1:31:46 |
| 53. | Skyrider | 13 | High on life playthrough part 7 | 36:42 |
| 54. | Da 40cal Killer | 13 | High on Life 1st playthrough Final Part. Ending and Secret Ending. | 1:40:36 |
| 55. | Shaun Kilgannon | 12 | High on Life - (No Commentary) - Play-through - Part 7 | 1:02:57 |
| 56. | VeryBadGamer. | 8 | High On Life Complete Playthrough #subscribe | 6:41:51 |
| 57. | WolfKinq | 7 | we need to help Knifey Find His Lost Parcel from his Hometown... | High on Knife DLC | Part 1 | 1:47:26 |
| 58. | Baggie Mark: An Average Gamer Plays... | 6 | High on Life SECRET ENDING !!!! | 9:30 |
| 59. | Fly-Wen-Ure-High | 6 | Fly-Wen-Ure-High Plays High on Life | 1:35:40 |
| 60. | Lsm Gaming | 5 | Talking Guns!! High On Life - Ep 1 | 56:10 |
| 61. | iiTz_xGriiMzo | 5 | high on life playthrough // part 3 | 1:19:17 |
| 62. | Hyped Gamer | 4 | Live VOD Hunting Douglas and Helping Dr Joopy | High On Life | 1:32:46 |
| 63. | Captain Neko | 4 | Wow! This Weapon Just Won't Stop Talking! | High On Life Blind Playthrough Part 1 | 0:00 |
| 64. | TEkSTA | 3 | High on Life Early Game Playthrough | 38:01 |
| 65. | Brinkstergaming | 2 | High On Life Lets Play part 1 | 3:56:12 |
