| 1. |  Zalzar | Don't Hug Me I'm Scared 4 REACTION! | THIS IS SO MESSED UP!!! | | 250,219 | |
| 2. | Adam | Mass Effect: The Normandy Theme (Extra Long Extended Version) | 212,838 | |
| 3. | jj0ck33 | Generic Mass Effect 1 Gameplay | 186,070 | |
| 4. | MrHulthen | the curse of being a Mass Effect fan | 154,833 | |
| 5. | MrHulthen | Mass Effect 4 | EVERYTHING We Know (So Far) | 70,347 | |
| 6. | YlvaJo | Shepard + Garrus | Salvation (Mass Effect) | 56,425 | |
| 7. | MrHulthen | Mass Effect 4 - BioWare Confirms 5 HINTS in Official Poster & Opens Up about Company Future | 52,000 | |
| 8. | MrHulthen | Mass Effect 4 Just Got an Official Poster! (Secrets & Hidden Details Breakdown) | 51,478 | |
| 9. | jj0ck33 | Mass Effect - (Attempting to) Not recruit Garrus | 48,568 | |
| 10. | MrHulthen | Bioware Opens Up About Development For Mass Effect 4, Dragon Age 4 & What It Means For the Future | 44,305 | |
| 11. | BlueberryPoot | We don't have time to deal with this idiot! | Mass Effect: Legendary Edition | 41,159 | |
| 12. | MrHulthen | Top 5 BIGGEST Theories About Mass Effect 4 | 37,273 | |
| 13. | MrHulthen | Mass Effect - What IF The Council had Backed Shepard COMPLETELY? | 33,566 | |
| 14. | MrHulthen | This Theory Explains one of the BIGGEST Questions About the Next Mass Effect | 32,995 | |
| 15. | MrHulthen | This Detail Could Mean Something HUGE For the Next Mass Effect | 31,927 | |
| 16. | MrHulthen | This Could Be the MYSTERY PLANET in the Mass Effect 4 Teaser Trailer | 29,254 | Preview |
| 17. | Pontus Hultgren Music | Mass Effect - Uncharted Worlds - Remix | 23,645 | |
| 18. | MrHulthen | Could the Reapers Return in Mass Effect 4? | 23,531 | |
| 19. | MrHulthen | MASSIVE NEWS! | MASS EFFECT IS GETTING A TV-SERIES! | 20,815 | |
| 20. | MrHulthen | Mass Effect 4 | Breaking Down Theories W/@BigDanGaming | PART 1 | 20,424 | |
| 21. | MrHulthen | Mass Effect 4 | Project Director Michael Gamble FINALLY Responds to the Teaser Trailer Removal | 20,356 | Preview |
| 22. | MrHulthen | 5 Things That Could Make The Next Mass Effect AMAZING | 17,863 | |
| 23. | MrHulthen | THIS Is What Mass Effect 4 COULD Look like in Unreal Engine 5 | 17,238 | |
| 24. | Marugitto | Tali (Mass Effect) cosplay performance - cosplay SM 2017 | 14,882 | |
| 25. | MrHulthen | 6 AWESOME Storylines We Could See in the Mass Effect TV-Series (20K Sub Special) | 14,817 | |
| 26. | MrHulthen | HUGE NEWS | Mass Effect 4 Using the Unreal Engine Is EVEN MORE Likely | 14,596 | |
| 27. | MrHulthen | The Future of This Channel | 12,623 | |
| 28. | The Skroologist | Short-Tut #54: How to Download and Install// Mass Effect (2007)ALL DLC'S - FREE DOWNLOAD | 10,541 | Tutorial |
| 29. | MrHulthen | Mass Effect 4 HUGE NEWS - UNREAL ENGINE 5 HAS BEEN CONFIRMED! | 9,713 | |
| 30. | MrHulthen | The Next Mass Effect | Live Reading of The Frozen Shepard Theory | 8,796 | |
| 31. | MrHulthen | Mass Effect: The TV-Series - Henry Cavill IS INTERESTED! | 8,219 | |
| 32. | Salooverall | SPORE: Mass Effect Harbinger (No mods::Timelapse::No Expansionpacks) | 7,788 | |
| 33. | Curaidh Plays Games | Прохождение Mass Effect - 01 - Создание Персонажа и Начало Игры | 7,436 | |
| 34. | MrHulthen | Will Mass Effect 4 be at the Game Awards 2021? | 7,309 | |
| 35. | The Nightsong | ME ~ Trilogy | The Guardian (Shepard) | The Nightingale | 6,267 | Vlog |
| 36. | MrHulthen | Let's talk some Mass Effect 4 Theories! | 6,193 | Discussion |
| 37. | MrHulthen | RPG News and the state of Youtube with @BigDanGaming | 5,707 | |
| 38. | MrHulthen | Mass Effect & God of War are Getting Made Into TV-Shows - By Amazon... | 5,172 | Show |
| 39. | Elajjaz Archive | Elajjaz - Mass Effect - Part 1 | 4,942 | |
| 40. | MrHulthen | Let's chat! | Mass Effect Monday | 4,666 | |
| 41. | ESA Speedrunning | Mass Effect [Any%] by AlecK47 - #ESACoronaRelief | 4,648 | |
| 42. | MrHulthen | What Happened to the Next Mass Effect Teaser!? | 4,595 | Preview |
| 43. | Oller Music | ♫ Mass Effect Ilos Battle (Oller Remix) ♫ Mass Effect OST Soundtrack Theme Remix Epic Electronic Mix | 4,102 | |
| 44. | TechnoZen Gaming | Mass Effect Legendary Edition - Adjusting PS5 HDR Settings | 3,570 | |
| 45. | Jellyzaur | Renegade playthrough || Mass Effect: Legendary Edition / Part 1 | 3,389 | Let's Play |
| 46. | MrHulthen | End of the Year RECAP | Let's chat Mass Effect 4, Dragon Age, Cyberpunk 2077 & Witcher | 3,342 | |
| 47. | Fuzion Xbox Testing | Mass Effect: Legendary Edition - Xbox One S Gameplay | 2,788 | |
| 48. | The Nightsong | ME ~ 2 & 3 | Memories (Shrios) | The Nightingale | 2,468 | |
| 49. | The Nightsong | ME ~ Trilogy | In Memory (of our family) | The Nightingale | 2,128 | Vlog |
| 50. | Elajjaz Archive | Elajjaz - Mass Effect - Part 2 | 2,100 | |
| 51. | Curaidh Plays Games | Прохождение Mass Effect - 02 - Найлус, Сарен и Ретранслятор | 2,023 | |
| 52. | Curaidh Plays Games | Прохождение Mass Effect - 21 - Астероид X57 и Минное Поле | 1,791 | |
| 53. | MrHulthen | Mass Effect Legendary Edition Coming to XBOX GAME PASS? | 1,790 | |
| 54. | Elajjaz Archive | Elajjaz - Mass Effect - Part 3 | 1,788 | |
| 55. | Anemone | What The Geth Doing #shorts | 1,575 | |
| 56. | The Nightsong | ME ~ Trilogy | In Freedom’s Name (Post Reaper War) | The Nightingale | 1,522 | Vlog |
| 57. | Curaidh Plays Games | Прохождение Mass Effect - 03 - Слоники, Спутница и Совет Цитадели | 1,426 | |
| 58. | Elina | When Mass Effect Doesn't go as Planned #shorts | 1,307 | |
| 59. | Valpskott | Valpcast V2 - Missuppfattningar | 1,298 | Let's Play |
| 60. | The Nightsong | Crossover | ME ~ DA | Stand My Ground | The Nightingale | 1,281 | |
| 61. | Curaidh Plays Games | Прохождение Mass Effect - 04 - Сканирование Хранителей, Проповедник и Харкин | 1,249 | |
| 62. | Curaidh Plays Games | Прохождение Mass Effect - 25 - Ферос (Геты и Корабль Гетов) | 1,153 | |
| 63. | Curaidh Plays Games | Прохождение Mass Effect - 26 - Ферос (Торианин) | 1,063 | |
| 64. | Curaidh Plays Games | Прохождение Mass Effect - 11 - Терум и Спасение Лиары | 1,007 | |
| 65. | Curaidh Plays Games | Прохождение Mass Effect - 05 - Новый Союзник (Вызволение Рекса) и Замысел Шорбана | 993 | |
| 66. | The Nightsong | ReMaster | ME ~ Legendary Edition | Come back alive (Shakarian) | The Nightingale | 980 | |
| 67. | Beyond Reality [CD10] | Mass Effect - Ep 26 - "Can't I have both?" | 975 | |
| 68. | jj0ck33 | jj0ck33 plays: Mass Effect - Before Eden Prime (1/2) | 963 | Let's Play |
| 69. | The Gaming Cathedral | MASS EFFECT - Movie [Swedish subtitles] | 962 | |
| 70. | Salooverall | SPORE: Mass Effect Hanar (No mods::Timelapse::No Expansionpacks) | 960 | |
| 71. | Curaidh Plays Games | Прохождение Mass Effect - 08 - Получаем Нормандию и Исследуем Планету Требин | 880 | |
| 72. | Curaidh Plays Games | Прохождение Mass Effect - 06 - Штурм Бара Фиста и Тали-Зора нар Райа (новый союзник) | 876 | |
| 73. | Curaidh Plays Games | Прохождение Mass Effect - 07 - Проблемы Дженны, Челлик и Контрабандист Якс | 847 | |
| 74. | uHD | [HDR 4K] Mass Effect 1 Legendary Edition | Sharjila | 842 | |
| 75. | Dave Parsec | David's YouTube Channel Introduction (outdated) | 821 | |
| 76. | bias60gaming | First Time Playing - Mass Effect Blind Playthrough E:1 | 814 | Let's Play |
| 77. | Jellyzaur | Renegade playthrough - making some horrible choices || Mass Effect Legendary Edition / Part 2 | 798 | Let's Play |
| 78. | Curaidh Plays Games | Прохождение Mass Effect - 48 - Цитадель в Огне, Бой с Сареном и Концовка Игры | 798 | |
| 79. | Curaidh Plays Games | Прохождение Mass Effect - 10 - Шардзила и Терум (начало) | 777 | |
| 80. | Elajjaz Archive | Elajjaz - Every Mass Effect Legendary Edition clip 2022 | 760 | |
| 81. | jj0ck33 | Mass Effect Legendary Edition: Eden Prime Finale | 742 | |
| 82. | Hyde209 VGM Remixer | Mass Effect - Beyond Space Remix | 734 | |
| 83. | Newbie Gammer | JOHN SHEPARD | Mass Effect 1 Legendary Edition Let’s Play Part 1 | 724 | Let's Play |
| 84. | Curaidh Plays Games | Прохождение Mass Effect - 09 - Биотики с Онтарио и Вылазка на Эдоп | 721 | |
| 85. | Newbie Gammer | MASS EFFECT 2 LEGENDARY EDITION Walkthrough Gameplay Part 2: NEW NORMANDY (FULL GAME) | 712 | Walkthrough |
| 86. | Curaidh Plays Games | Прохождение Mass Effect - 22 - Астероид X57 (окончание) и Быстрый Визит на Цитадель | 706 | |
| 87. | Curaidh Plays Games | Прохождение Mass Effect - 12 - Эта Хокинга (высадка на Пресроп) | 679 | |
| 88. | Curaidh Plays Games | Прохождение Mass Effect - 36 - Заканчиваем Дела на Цитадели и Угоняем Нормандию | 645 | |
| 89. | Curaidh Plays Games | Прохождение Mass Effect - 13 - Новерия (Туманность Конская Голова) | 641 | |
| 90. | The Nightsong | Funny compilation part 9 | I should go | Mass Effect ~ OG Trilogy | 636 | Vlog |
| 91. | Newbie Gammer | MASS EFFECT 2 LEGENDARY EDITION Walkthrough Gameplay Part 3: ARCHANGEL (FULL GAME) | 628 | |
| 92. | Curaidh Plays Games | Прохождение Mass Effect - 24 - Ферос (Надежда Чжу) | 611 | |
| 93. | Dave Parsec | David reacts to E3 - Dragon Age and Mass Effect | 596 | |
| 94. | Newbie Gammer | MASS EFFECT 2 LEGENDARY EDITION Walkthrough Gameplay Part 4: MORDIN SOLUS (FULL GAME) | 588 | |
| 95. | Newbie Gammer | MASS EFFECT 2 LEGENDARY EDITION Walkthrough Gameplay Part 5: BLOOD PACK BOOM AQUAD (FULL GAME) | 583 | |
| 96. | Newbie Gammer | MASS EFFECT 2 LEGENDARY EDITION Walkthrough Gameplay Part 6: CITADEL (FULL GAME) | 583 | |
| 97. | Curaidh Plays Games | Прохождение Mass Effect - 16 - Новерия - Станиця "Расселина" и Матриарх Бенезия | 579 | |
| 98. | Newbie Gammer | MASS EFFECT 2 LEGENDARY EDITION Walkthrough Gameplay Part 7: KASUMI LOYALTY MISSION (FULL GAME) | 579 | |
| 99. | Curaidh Plays Games | Прохождение Mass Effect - 35 - Вермайр - Сложный Выбор и Битва с Сареном | 576 | |
| 100. | Curaidh Plays Games | Прохождение Mass Effect - 14 - Новерия - Разоблачение Анолеиса и Поездка к Горе | 568 | |
