| 2024-05-20 |  MAME-FAN | Mutation Nation Arcade Cabinet MAME Playthrough w/ Marquee | 46:20 | 312 |
| 2024-05-09 |  PSB Gameplay | Mutation Nation-Playthrough Full (2 Players) "Ricky Jones & Johnny Hart" | 35:21 | 111 |
| 2024-03-13 | Retrogamer 41(SepiaMetanoia) | Mutation Nation(Arcade) - Full Playthrough. | 33:03 | 469 |
| 2024-03-07 |  Gaming on the Brain | Playthrough WC - Mutation Nation - Neo Geo MVS / Arcade [ミューテイションネイション] | 38:50 | 64 |
| 2024-03-07 | Gaming on the Brain | Playthrough - Mutation Nation - Neo Geo MVS / Arcade | 38:32 | 155 |
| 2024-02-19 | Randomised Gaming | Mutation Nation Arcade Archive NEO GEO Playthrough on PlayStation 4 (PS4) [4K60] | 41:34 | 98 |
| 2024-01-18 | Kiss My Robot | Mutation Nation - Playthrough - Arcade/Neo-Geo | 45:36 | 8 |
| 2024-01-10 |  Longplays Retro | playthrough Mutation Nation (NEOGEO) | 44:19 | 18 |
| 2023-10-31 | jiggajuice17 | Mutation Nation Arcade PC Gameplay | 1:00 | 8 |
| 2023-10-22 | Retro Gaming with Olivia J | Mutation Nation (Neo Geo) - Playthrough - Live Stream with Olivia J | 47:30 | 87 |
| 2023-07-27 | Retro Games Squad | Mutation Nation Arcade longlpay | 40:54 | 7 |
| 2023-05-01 |  Zabdi Plays | Kyo vs los mutantes | Mutation Nation (Arcade) completo | 44:49 | 34 |
| 2023-03-11 | Oliver Harper's Lets Play Retro | Mutation Nation (Neo Geo) Let's Play Retro | 45:17 | 490 |
| 2023-02-26 | Vintage Cartridge Gaming | Mutation Nation (Neo Geo) (Playthrough) | 41:19 | 1 |
| 2022-11-18 | 1up Retro Gaming | Let's Play Guess The Game In 10 Seconds Part 17 #shorts #gaming #trivia #quiz | 0:13 | 61 |
| 2022-11-12 | EctogamesTV | Mutation Nation- Full Playthrough | 39:21 | 120 |
| 2022-11-04 |  By Urien84 Longplays | Mutation Nation Arcade Longplay HD HQ By Urien84 | 42:19 | 46 |
| 2022-10-29 | Angry Old Man Gaming Official | Highlight: Mutation Nation (Arcade-1992) First playthrough Final Boss | 4:59 | 1 |
| 2022-10-13 | PSB Gameplay | Mutation Nation-Playthrough Full | 39:45 | 42 |
| 2022-09-22 | XtraKetsup | Mutation Nation Arcade Playthrough | 40:07 | 3 |
| 2022-06-25 | DoubleRGaming | NEOGEO MUTATION NATION Playthrough Part 2 | 5:19 | 12 |
| 2022-06-25 | DoubleRGaming | NEOGEO MUTATION NATION Playthrough Part 1 | 6:43 | 7 |
| 2022-06-21 | SolidSnake | #shorts Mutation Nation retrogame | full playthrough link in first comment | 0:16 | 470 |
| 2022-05-02 | NastyBedazzler | Freak Saturation Across The Nation- Mutation Nation on the Neo Geo Nasty Playthrough | 29:18 | 72 |
| 2021-09-15 | Noize Games Production | Sans Prise De Tête ! Gameplay Mutation Nation ! massacré par des poulpes et des crevettes ! | 25:53 | 125 |
| 2021-06-15 |  AyorSaeba | [Rediff][Let's Play] Mutation Nation (Neo Geo CD) | 43:18 | 426 |
| 2021-06-04 |  Videogems | Let's Play!! Mutation Nation (Neo Geo) Mit Joe von Videospielplatz (GERMAN) | 38:27 | 148 |
| 2021-04-06 | Super Omnibox | Use the Lethal Death Blow! ~ Mutation Nation (Arcade) | 6:25 | 7 |
| 2021-02-20 | This Round's on Me | The Co-op Couch - Mutation Nation - Full Playthrough | 40:14 | 100 |
| 2020-06-19 | Retro Playbacks | Mutation Nation / SNK NEO GEO AES/ RGB Framemeister Full Playthrough | 39:52 | 31 |
| 2020-03-28 | Terry Goodwin | Mutation Nation (1992 / NeoGeo MVS / PS4) - Complete 1P Playthrough | 41:22 | 23 |
| 2019-11-08 |  MarcBlaster The Gamer | Mutation Nation (Arcade) - Playthrough | 40:01 | 30 |
| 2018-10-29 | Jeymis Peixoto | Mutation Nation Playthrough | 34:17 | 23 |
| 2018-09-15 |  Gaming Jay | Mutation Nation (Neo Geo) - The 90's Beat Em Up That Consoles Needed - Saturday Afternoon Gaming | 47:06 | 587 |
| 2018-08-18 | VERISIMILITUDE | ACA NEOGEO MUTATION NATION: SOLO ARCADE PLAYTHROUGH | 44:28 | 23 |
| 2018-07-01 |  Aussie Freak Gamers | Pandora's Box 5 Mutation Nation Complete Gameplay Playthrough | 48:34 | 186 |
| 2018-01-22 | Cerberus LetsPlay | Mutation Nation - Full Playthrough (NEOGEO) | 54:37 | 85 |
| 2018-01-05 | StarRoad | [SEXTA CLÁSSICA 8] Fightcade - jogatina com o Allanz Plays ! | 4:08:38 | 262 |
| 2017-12-16 | Termos de Urso | Let's Play com o Amer: Mutation Nation | 38:40 | 1,206 |
| 2017-10-29 | smbhax 2000 | (PS4 60fps) ACA NEOGEO Mutation Nation - co-op play-through 10/29/17 | 44:48 | 513 |
| 2017-10-26 | Rєαl Ɓєηנαмιllιση | Mutation Nation playthrough | 38:34 | 15 |
| 2017-10-20 | 1 Coin Only | Mutation Nation (Arcade) - Full Playthrough and Ending | 36:22 | 87 |
| 2016-12-25 | TheInnocentSinful | Mutation Nation (Arcade) Full Playthrough | 37:59 | 16,375 |
| 2016-10-15 | Felipe Nascimento | Mutation Nation (Arcade) 2P Cooperative Playthrough | 35:22 | 645 |
| 2015-11-04 | White Boy Gaming | Mutation Nation Arcade (1991) Playthrough! | 35:42 | 165 |
| 2013-09-08 | KITT171 | Retroplays: Mutation Nation (Neo Geo) | 5:27 | 195 |
| 2013-03-19 | Chilean Retrogamer | Mutation Nation (Arcade / Neogeo) - Full Playthrough | 37:10 | 520 |
| 2012-03-12 |  Ars Magna 【黄金練成】 | Mutation Nation : Arcade playthrough [Part 1] | 20:40 | 8,029 |
| 2011-11-03 | Hiro Konobu | Mutation Nation Playthrough Part 5 | 8:30 | 11 |
| 2011-11-03 | Hiro Konobu | Mutation Nation Playthrough Part 4 | 6:57 | 3 |
| 2011-11-03 | Hiro Konobu | Mutation Nation Playthrough Part 3 | 8:16 | 6 |
| 2011-11-03 | Hiro Konobu | Mutation Nation Playthrough Part 2 | 6:12 | 13 |
| 2011-11-03 | Hiro Konobu | Mutation Nation Playthrough Part 1 | 11:19 | 40 |
| 2010-09-18 | VideoGameStupid | Let's Play - Mutation Nation Part 1 | 14:56 | 472 |
| 2010-03-09 | bambooie | Playthrough No 17. Mutation Nation | 5:06 | 264 |
