| 1. |  TheInnocentSinful | 35,762 | Mutation Nation (Arcade) Full Playthrough | 37:59 |
| 2. |  Ars Magna 【黄金練成】 | 8,029 | Mutation Nation : Arcade playthrough [Part 1] | 20:40 |
| 3. |  KrzychoMK | 3,239 | Mutation Nation playthrough | 42:43 |
| 4. |  davpreec | 1,419 | Streets of Rage Remake - Mutation Nation - Playthrough | 1:15:30 |
| 5. |  Termos de Urso | 1,206 | Let's Play com o Amer: Mutation Nation | 38:40 |
| 6. | Oliver Harper's Lets Play Retro (LetsPlayRetro) | 691 | Mutation Nation (Neo Geo) Let's Play Retro | 45:17 |
| 7. | Felipe Nascimento | 645 | Mutation Nation (Arcade) 2P Cooperative Playthrough | 35:22 |
| 8. |  Gaming Jay | 587 | Mutation Nation (Neo Geo) - The 90's Beat Em Up That Consoles Needed - Saturday Afternoon Gaming | 47:06 |
| 9. | Chilean Retrogamer | 520 | Mutation Nation (Arcade / Neogeo) - Full Playthrough | 37:10 |
| 10. | smbhax 2000 | 513 | (PS4 60fps) ACA NEOGEO Mutation Nation - co-op play-through 10/29/17 | 44:48 |
| 11. | Retrogamer 41(SepiaMtADogma) | 474 | Mutation Nation(Arcade) - Full Playthrough. | 33:03 |
| 12. | VideoGameStupid | 472 | Let's Play - Mutation Nation Part 1 | 14:56 |
| 13. | SolidSnake | 470 | #shorts Mutation Nation retrogame | full playthrough link in first comment | 0:16 |
| 14. |  AyorSaeba | 426 | [Rediff][Let's Play] Mutation Nation (Neo Geo CD) | 43:18 |
| 15. | MAME-FAN | 415 | Mutation Nation Arcade Cabinet MAME Playthrough w/ Marquee | 46:20 |
| 16. | Retronomicon | 281 | Sengoku 3 - Neo Geo Playthrough (4k 60FPS) | 1:13:17 |
| 17. | bambooie | 265 | Playthrough No 17. Mutation Nation | 5:06 |
| 18. | StarRoad | 262 | [SEXTA CLÁSSICA 8] Fightcade - jogatina com o Allanz Plays ! | 4:08:38 |
| 19. | Gaming on the Brain | 219 | Playthrough WC - Mutation Nation - Neo Geo MVS / Arcade [ミューテイションネイション] | 38:50 |
| 20. |  Aussie Freak Gamers | 186 | Pandora's Box 5 Mutation Nation Complete Gameplay Playthrough | 48:34 |
| 21. | Ashgabat Cat | 174 | Let's Play Zintrick | Arcade Calvacade | 14:44 |
| 22. |  PSB Gameplay | 166 | Mutation Nation-Playthrough Full (2 Players) "Ricky Jones & Johnny Hart" | 35:21 |
| 23. | White Boy Gaming | 165 | Mutation Nation Arcade (1991) Playthrough! | 35:42 |
| 24. | Noize Games Production | 125 | Sans Prise De Tête ! Gameplay Mutation Nation ! massacré par des poulpes et des crevettes ! | 25:53 |
| 25. | EctogamesTV | 120 | Mutation Nation- Full Playthrough | 39:21 |
| 26. | Randomised Gaming | 113 | Mutation Nation Arcade Archive NEO GEO Playthrough on PlayStation 4 (PS4) [4K60] | 41:34 |
| 27. | This Round's on Me | 100 | The Co-op Couch - Mutation Nation - Full Playthrough | 40:14 |
| 28. | Olivia J's Retro Gaming Corner | 94 | Mutation Nation (Neo Geo) - Playthrough - Live Stream with Olivia J | 47:30 |
| 29. | 1 Coin Only | 87 | Mutation Nation (Arcade) - Full Playthrough and Ending | 36:22 |
| 30. | CERBERUS GAMING | 85 | Mutation Nation - Full Playthrough (NEOGEO) | 54:37 |
| 31. | Hiro Konobu | 73 | Mutation Nation Playthrough Part 5 | 8:30 |
| 32. | Nastybedazzler | 72 | Freak Saturation Across The Nation- Mutation Nation on the Neo Geo Nasty Playthrough | 29:18 |
| 33. | 1up Retro Gaming | 61 | Let's Play Guess The Game In 10 Seconds Part 17 #shorts #gaming #trivia #quiz | 0:13 |
| 34. | By Urien84 Longplays | 46 | Mutation Nation Arcade Longplay HD HQ By Urien84 | 42:19 |
| 35. |  Zabdi Plays | 34 | Kyo vs los mutantes | Mutation Nation (Arcade) completo | 44:49 |
| 36. |  Retro Playbacks | 31 | Mutation Nation / SNK NEO GEO AES/ RGB Framemeister Full Playthrough | 39:52 |
| 37. | VERISIMILITUDE | 23 | ACA NEOGEO MUTATION NATION: SOLO ARCADE PLAYTHROUGH | 44:28 |
| 38. | DoubleRGaming | 19 | NEOGEO MUTATION NATION Playthrough Part 2 | 5:19 |
| 39. | Longplays Retro | 18 | playthrough Mutation Nation (NEOGEO) | 44:19 |
| 40. | Rєαl Ɓєηנαмιllιση | 15 | Mutation Nation playthrough | 38:34 |
| 41. | jiggajuice17 | 8 | Mutation Nation Arcade PC Gameplay | 1:00 |
| 42. | Kiss My Robot | 8 | Mutation Nation - Playthrough - Arcade/Neo-Geo | 45:36 |
| 43. | Retro Games Squad | 7 | Mutation Nation Arcade longlpay | 40:54 |
| 44. | Super Omnibox | 7 | Use the Lethal Death Blow! ~ Mutation Nation (Arcade) | 6:25 |
| 45. | XtraKetsup | 3 | Mutation Nation Arcade Playthrough | 40:07 |
| 46. | Vintage Cartridge Gaming | 1 | Mutation Nation (Neo Geo) (Playthrough) | 41:19 |
| 47. | Angry Old Man Gaming Official | 1 | Highlight: Mutation Nation (Arcade-1992) First playthrough Final Boss | 4:59 |
