| 1. |  Boss Fight Database | No More Heroes 2: All Bosses and Ending (4K 60fps) (Dolphin Emulator) | 4,542 | Let's Play |
| 2. | Boss Fight Database | No More Heroes 2: Margaret Boss Fight (Dolphin 4K 60fps) | 4,193 | Let's Play |
| 3. | Boss Fight Database | No More Heroes 2: Kimmy Howell Secret Boss Fight (Dolphin 4K 60fps) | 3,698 | Let's Play |
| 4. | Boss Fight Database | No More Heroes 2: Mimmy Boss Fight (Dolphin 4K 60fps) | 1,787 | Let's Play |
| 5. | Boss Fight Database | No More Heroes 2: Alice Moonlight Boss Fight (Dolphin 4K 60fps) | 1,722 | Let's Play |
| 6. | Boss Fight Database | No More Heroes 2: Jasper Batt Jr Final Boss Fight and Ending (Dolphin 4K 60fps) | 1,721 | Let's Play |
| 7. | Boss Fight Database | No More Heroes 2: New Destroyman Boss Fight (Dolphin 4K 60fps) | 1,580 | Let's Play |
| 8. | Boss Fight Database | No More Heroes 2: Cloe Walsh Boss Fight (Dolphin 4K 60fps) | 1,128 | Let's Play |
| 9. | Boss Fight Database | No More Heroes 2: Charlie MacDonald Boss Fight (Dolphin 4K 60fps) | 1,113 | Let's Play |
| 10. | Boss Fight Database | No More Heroes 2: Matt Helms Boss Fight (Dolphin 4K 60fps) | 1,062 | Let's Play |
| 11. | Boss Fight Database | No More Heroes 2: Skelter Helter Boss Fight (Dolphin 4K 60fps) | 1,059 | Let's Play |
| 12. | Boss Fight Database | No More Heroes 2: Captain Vladimir Boss Fight (Dolphin 4K 60fps) | 977 | Let's Play |
| 13. | Boss Fight Database | No More Heroes 2: Dr Letz Shake Boss Fight (Dolphin 4K 60fps) | 860 | Let's Play |
| 14. |  rabbidluigi | 'Fashionably Late' - No More Heroes 2: Desperate Struggle [#1] | 825 | Let's Play |
| 15. | Boss Fight Database | No More Heroes 2: Ryuji Boss Fight (Dolphin 4K 60fps) | 753 | Let's Play |
| 16. | Boss Fight Database | No More Heroes 2: Million Gunman Boss Fight (Dolphin 4K 60fps) | 551 | Let's Play |
| 17. | rabbidluigi | 'Rhythm and Blues' - No More Heroes 2: Desperate Struggle [#2] | 478 | Let's Play |
| 18. | rabbidluigi | 'Retrograde Inversion' - No More Heroes 2: Desperate Struggle [#3] | 424 | Let's Play |
| 19. | rabbidluigi | 'Field Goals' - No More Heroes 2: Desperate Struggle [#4] | 402 | Let's Play |
| 20. | rabbidluigi | 'Anime Isn't Real' - No More Heroes 2: Desperate Struggle [#12] | 396 | Let's Play |
| 21. | rabbidluigi | 'Bad Omens' - No More Heroes 2: Desperate Struggle [#6] | 385 | Let's Play |
| 22. | rabbidluigi | 'High Steaks' - No More Heroes 2: Desperate Struggle [#5] | 379 | Let's Play |
| 23. | rabbidluigi | 'Seismic Shift' - No More Heroes 2: Desperate Struggle [#9] | 377 | Let's Play |
| 24. | rabbidluigi | 'Sucker Punch' - No More Heroes 2: Desperate Struggle [FINALE] | 377 | Let's Play |
| 25. | rabbidluigi | 'Catchy Tunes' - No More Heroes 2: Desperate Struggle [#13] | 366 | Let's Play |
| 26. | rabbidluigi | 'Career Advice' - No More Heroes 2: Desperate Struggle [#7] | 366 | Let's Play |
| 27. | rabbidluigi | 'Weakly Acidic' - No More Heroes 2: Desperate Struggle [#8] | 353 | Let's Play |
| 28. | rabbidluigi | 'Cold Pizza' - No More Heroes 2: Desperate Struggle [#16] | 349 | Let's Play |
| 29. | rabbidluigi | 'Crownless King' - No More Heroes 2: Desperate Struggle [#15] | 348 | Let's Play |
| 30. | rabbidluigi | 'Schizoid Man' - No More Heroes 2: Desperate Struggle [#11] | 338 | Let's Play |
| 31. | John GodGames | No More Heroes 2: Desperate Struggle - Gameplay Wii 4K 2160p (Dolphin 5.0) | 338 | Let's Play |
| 32. | NicoB | REVENGE OF THE WEEB - No More Heroes 2: Desperate Struggle | 336 | Let's Play |
| 33. | rabbidluigi | 'Ground Control' - No More Heroes 2: Desperate Struggle [#14] | 327 | Let's Play |
| 34. | rabbidluigi | 'Cash Prizes' - No More Heroes 2: Desperate Struggle [#10] | 309 | Let's Play |
| 35. | rabbid2igi | HIGHLIGHTS: Let's Play No More Heroes 2: Desperate Struggle | 195 | Let's Play |
| 36. | Zorrin小崎 | Travis vs Henry! Fake and Real Ending! | No More Heroes Ep. Finale Lets Play & Reaction (Switch Ver) | 192 | Let's Play |
| 37. | Zorrin小崎 | The Truth about Travis! | No More Heroes Ep.4 Lets Play & Reaction (Switch Ver) | 185 | Let's Play |
| 38. | Zorrin小崎 | This Final Boss is Frustrating!!! | NMH2 Desperate Struggle Finale Lets Play/Reaction (Switch Ver) | 155 | Let's Play |
| 39. | Zorrin小崎 | Margaret & Alice is so... Sublime! | NMH2 Desperate Struggle Ep.4 Lets Play/Reaction (Switch Ver) | 152 | Let's Play |
| 40. | Zorrin小崎 | Fighting a Yandere! (Secret Boss) | NMH2 Desperate Struggle Ep.3 Lets Play/Reaction (Switch Ver) | 150 | Let's Play |
| 41. | Zorrin小崎 | It's been so long! Dr. Letz Shake is Back! | NMH2 Desperate Struggle Ep2 Lets Play/Reaction (Switch) | 130 | Let's Play |
| 42. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S7 - Pervy Teacher | 127 | Let's Play |
| 43. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S3 | 124 | Let's Play |
| 44. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S2 P 2 | 123 | Let's Play |
| 45. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S2 P1 | 119 | Let's Play |
| 46. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S1 (sound fixed) | 114 | Let's Play |
| 47. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S5 P2 | 106 | Let's Play |
| 48. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S8 | 104 | Let's Play |
| 49. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S9 P2 | 104 | Let's Play |
| 50. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S9 P1 | 104 | Let's Play |
| 51. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S11 | 104 | Let's Play |
| 52. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S10 P1 | 98 | Let's Play |
| 53. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S5 P1 | 97 | Let's Play |
| 54. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S10 P2 | 97 | Let's Play |
| 55. | Kyzers Game Zone | Enter the Struggle - Kyzer Plays No More Heroes 2 - Part 1 [K.A.T.V.] | 94 | Let's Play |
| 56. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S6 P2 | 90 | Let's Play |
| 57. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S12 P2 - The End | 90 | Let's Play |
| 58. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S6 P1 | 88 | Let's Play |
| 59. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S4 P2 | 86 | Let's Play |
| 60. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S4 P1 | 85 | Let's Play |
| 61. | Kyzers Game Zone | Beam Vs Blade - Kyzer Plays No More Heroes - Part 3 [K.A.T.V.] | 83 | Let's Play |
| 62. | MuzikB0x | Let's Play No More Heroes 2 : Desperate Struggle FR - Ep 1 - "Gelée Bizarre 5"... hum hum ! | 81 | Let's Play |
| 63. |  Turner459O | Let's Play No More Heroes 2 - Part 1 - Fashionably Late | 80 | Let's Play |
| 64. | LuizPrower | The Playthrough that never was | 80 | Let's Play |
| 65. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S12 P1 - The End | 67 | Let's Play |
| 66. | Kyzers Game Zone | Destroy Fail - Kyzer Plays No More Heroes - Part 4 [K.A.T.V.] | 65 | Let's Play |
| 67. |  NOVEL • VTubers FR | ZIZOU LE ZIZI ! (No More Heroes 2) | Selph1ne | VTUBER FR | 60 | Let's Play |
| 68. | Kyzers Game Zone | Beat Blasting - Kyzer Plays No More Heroes 2 - Part 2 [K.A.T.V.] | 58 | Let's Play |
| 69. | PowerJ - Let's Player | [FR] #1 Let's play No More Heroes 2 : Desperate Struggle - Roi sans Couronne | 57 | Let's Play |
| 70. | ShadowSoul1305 | World is Playground ~ Lp Theme Park Projekt *Part 4* | 53 | Let's Play |
| 71. | Turner459O | Let's Play No More Heroes 2 - Part 2 - The Ultimate Vengeance! | 48 | Let's Play |
| 72. | Kyzers Game Zone | Letz Shake - Kyzer Plays No More Heroes - Part 6 [K.A.T.V.] | 46 | Let's Play |
| 73. |  GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #1 - The Return of Travis Touchdown | 45 | Let's Play |
| 74. | MuzikB0x | Let's Play No More Heroes 2 : Desperate Struggle FR - Ep 3 - Rangée de Boobs ! | 45 | Let's Play |
| 75. | Turner459O | Let's Play No More Heroes 2 - Part 5 - Huge Tracts of Land | 44 | Let's Play |
| 76. | Kyzers Game Zone | Scream Queen - Kyzer Plays No More Heroes 2 - Part 5 [K.A.T.V.] | 44 | Let's Play |
| 77. | Kyzers Game Zone | Death Parade - Kyzer Plays No More Heroes - Part 3 [K.A.T.V.] | 43 | Let's Play |
| 78. | MuzikB0x | Let's Play No More Heroes 2 : Desperate Struggle FR - Ep 2 - Avec Frosties, Le Tigre est en Toi ! | 43 | Let's Play |
| 79. | PowerJ - Let's Player | [FR] #4 Let's play No More Heroes 2 : Desperate Struggle - Salty Pizza [FIN] | 42 | Let's Play |
| 80. | Lotus Prince | Lotus Prince Let's Play: No More Heroes 2 Desperate Struggle - Part 2 | 42 | Let's Play |
| 81. | Kyzers Game Zone | Akashic Horror - Kyzer Plays No More Heroes - Part 4 [K.A.T.V.] | 41 | Let's Play |
| 82. | Turner459O | Let's Play No More Heroes 2 - Part 36 - Rank 1 ~ Jasper Batt Jr. | 41 | Let's Play |
| 83. | Kyzers Game Zone | Double Dunces - Kyzer Plays No More Heroes 2 - Part 8 [K.A.T.V.] | 40 | Let's Play |
| 84. | MuzikB0x | Let's Play No More Heroes 2 : Desperate Struggle FR - Ep 4 - Tu veux souffler dans ma Flûte ? | 39 | Let's Play |
| 85. | Kyzers Game Zone | Million Shots - Kyzer Plays No More Heroes 2 - Part 7 [K.A.T.V.] | 38 | Let's Play |
| 86. |  RV Gaming | FIX Lag No More Heroes 2 Gameplay Android - Dolphin Emulator Android | 37 | Let's Play |
| 87. | Turner459O | Let's Play No More Heroes 2 - Part 6 - LB Dollar Powah! | 37 | Let's Play |
| 88. | SonicBlueSky | 4 Years | 36 | Let's Play |
| 89. | Lotus Prince | Lotus Prince Let's Play: No More Heroes 2 - Part 6 | 35 | Let's Play |
| 90. | Kyzers Game Zone | School Crush - Kyzer Plays No More Heroes 2 - Part 9 [K.A.T.V.] | 35 | Let's Play |
| 91. | RageSelect | No More Heroes 2: Desperate Struggle (The Dojo) Let's Play | 33 | Let's Play |
| 92. | Turner459O | Let's Play No More Heroes 2 - Part 10 - Rank 49 - 25 ~ Charlie MacDonald & His Hoes | 33 | Let's Play |
| 93. | PowerJ - Let's Player | [FR] #2 Let's play No More Heroes 2 : Desperate Struggle - Le Film d'Horreur | 33 | Let's Play |
| 94. | Your Pal, Ral! | No More Heroes 2: Desperate Struggle (Blind) - Episode 1 "Return To Santa Destroy" | 32 | Let's Play |
| 95. | MuzikB0x | Let's Play No More Heroes 2 : Desperate Struggle FR - Ep 5 - Poison Ivy sors de ce Corps | 32 | Let's Play |
| 96. | Turner459O | Let's Play No More Heroes 2 - Part 4 - Plumber's Don't Wear Red Jackets | 32 | Let's Play |
| 97. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #2 - For Bishop!!! | 31 | Let's Play |
| 98. | PowerJ - Let's Player | [FR] #3 Let's play No More Heroes 2 : Desperate Struggle - Trinité de Tueurs | 31 | Let's Play |
| 99. | Kyzers Game Zone | Warriors Duel - Kyzer Plays No More Heroes 2 - Part 10 [K.A.T.V.] | 31 | Let's Play |
| 100. | Turner459O | Let's Play No More Heroes 2 - Part 33 - Rank 2 ~ Alice Twilight | 29 | Let's Play |
