| 1. |  Boss Fight Database | No More Heroes 2: All Bosses and Ending (4K 60fps) (Dolphin Emulator) | 409,526 | Let's Play |
| 2. | Boss Fight Database | No More Heroes 2: Margaret Boss Fight (Dolphin 4K 60fps) | 331,804 | Let's Play |
| 3. | Boss Fight Database | No More Heroes 2: Kimmy Howell Secret Boss Fight (Dolphin 4K 60fps) | 312,261 | Let's Play |
| 4. | Boss Fight Database | No More Heroes 2: Jasper Batt Jr Final Boss Fight and Ending (Dolphin 4K 60fps) | 166,189 | Let's Play |
| 5. | Boss Fight Database | No More Heroes 2: Mimmy Boss Fight (Dolphin 4K 60fps) | 135,779 | Let's Play |
| 6. | Boss Fight Database | No More Heroes 2: Alice Moonlight Boss Fight (Dolphin 4K 60fps) | 132,411 | Let's Play |
| 7. | Boss Fight Database | No More Heroes 2: New Destroyman Boss Fight (Dolphin 4K 60fps) | 131,452 | Let's Play |
| 8. | Boss Fight Database | No More Heroes 2: Cloe Walsh Boss Fight (Dolphin 4K 60fps) | 109,838 | Let's Play |
| 9. | Boss Fight Database | No More Heroes 2: Charlie MacDonald Boss Fight (Dolphin 4K 60fps) | 90,967 | Let's Play |
| 10. | Boss Fight Database | No More Heroes 2: Skelter Helter Boss Fight (Dolphin 4K 60fps) | 84,584 | Let's Play |
| 11. | Boss Fight Database | No More Heroes 2: Matt Helms Boss Fight (Dolphin 4K 60fps) | 79,517 | Let's Play |
| 12. | Boss Fight Database | No More Heroes 2: Dr Letz Shake Boss Fight (Dolphin 4K 60fps) | 71,937 | Let's Play |
| 13. | Boss Fight Database | No More Heroes 2: Captain Vladimir Boss Fight (Dolphin 4K 60fps) | 61,301 | Let's Play |
| 14. | Boss Fight Database | No More Heroes 2: Ryuji Boss Fight (Dolphin 4K 60fps) | 59,698 | Let's Play |
| 15. | John GodGames | No More Heroes 2: Desperate Struggle - Gameplay Wii 4K 2160p (Dolphin 5.0) | 55,373 | Let's Play |
| 16. | Boss Fight Database | No More Heroes 2: Million Gunman Boss Fight (Dolphin 4K 60fps) | 49,957 | Let's Play |
| 17. |  rabbidluigi | 'Fashionably Late' - No More Heroes 2: Desperate Struggle [#1] | 37,035 | Let's Play |
| 18. | rabbidluigi | 'Rhythm and Blues' - No More Heroes 2: Desperate Struggle [#2] | 20,297 | Let's Play |
| 19. | rabbidluigi | 'Anime Isn't Real' - No More Heroes 2: Desperate Struggle [#12] | 15,131 | Let's Play |
| 20. |  Turner459O | Let's Play No More Heroes 2 - Part 1 - Fashionably Late | 14,423 | Let's Play |
| 21. | rabbidluigi | 'High Steaks' - No More Heroes 2: Desperate Struggle [#5] | 14,338 | Let's Play |
| 22. | rabbidluigi | 'Field Goals' - No More Heroes 2: Desperate Struggle [#4] | 14,249 | Let's Play |
| 23. | rabbidluigi | 'Retrograde Inversion' - No More Heroes 2: Desperate Struggle [#3] | 13,953 | Let's Play |
| 24. | rabbidluigi | 'Seismic Shift' - No More Heroes 2: Desperate Struggle [#9] | 13,580 | Let's Play |
| 25. | nosound98 | No More Heroes 2: Desperate Struggle (Wii) on Dolphin Wii/GC Emulator 720p HD | 13,469 | Let's Play |
| 26. | rabbidluigi | 'Career Advice' - No More Heroes 2: Desperate Struggle [#7] | 13,013 | Let's Play |
| 27. | rabbidluigi | 'Catchy Tunes' - No More Heroes 2: Desperate Struggle [#13] | 12,711 | Let's Play |
| 28. | rabbidluigi | 'Bad Omens' - No More Heroes 2: Desperate Struggle [#6] | 12,658 | Let's Play |
| 29. | rabbidluigi | 'Weakly Acidic' - No More Heroes 2: Desperate Struggle [#8] | 12,346 | Let's Play |
| 30. | ShadowSoul1305 | World is Playground ~ Lp Theme Park Projekt *Part 4* | 12,288 | Let's Play |
| 31. | NicoB | REVENGE OF THE WEEB - No More Heroes 2: Desperate Struggle | 11,285 | Let's Play |
| 32. | rabbidluigi | 'Cold Pizza' - No More Heroes 2: Desperate Struggle [#16] | 11,279 | Let's Play |
| 33. | rabbidluigi | 'Sucker Punch' - No More Heroes 2: Desperate Struggle [FINALE] | 11,252 | Let's Play |
| 34. | rabbidluigi | 'Schizoid Man' - No More Heroes 2: Desperate Struggle [#11] | 11,127 | Let's Play |
| 35. | rabbidluigi | 'Crownless King' - No More Heroes 2: Desperate Struggle [#15] | 11,126 | Let's Play |
| 36. | rabbidluigi | 'Cash Prizes' - No More Heroes 2: Desperate Struggle [#10] | 10,564 | Let's Play |
| 37. | rabbidluigi | 'Ground Control' - No More Heroes 2: Desperate Struggle [#14] | 9,516 | Let's Play |
| 38. |  GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #1 - The Return of Travis Touchdown | 7,381 | Let's Play |
| 39. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S1 (sound fixed) | 7,081 | Let's Play |
| 40. | Turner459O | Let's Play No More Heroes 2 - Part 5 - Huge Tracts of Land | 6,607 | Let's Play |
| 41. | Turner459O | Let's Play No More Heroes 2 - Part 2 - The Ultimate Vengeance! | 6,402 | Let's Play |
| 42. | Rogue Mechanist | Bondage Kick - Let's Play No More Heroes 2: Desperate Struggle - Part 7 | 6,022 | Let's Play |
| 43. | Free Emulator | No More Heroes 2: Desperate Struggle | Dolphin Emulator 4.0.2 [1080p HD] | Nintendo Wii | 5,947 | Let's Play |
| 44. | Turner459O | Let's Play No More Heroes 2 - Part 36 - Rank 1 ~ Jasper Batt Jr. | 5,938 | Let's Play |
| 45. | LuizPrower | The Playthrough that never was | 5,797 | Let's Play |
| 46. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S2 P 2 | 5,320 | Let's Play |
| 47. | Zorrin小崎 | Fighting a Yandere! (Secret Boss) | NMH2 Desperate Struggle Ep.3 Lets Play/Reaction (Switch Ver) | 5,318 | Let's Play |
| 48. | Zorrin小崎 | The Truth about Travis! | No More Heroes Ep.4 Lets Play & Reaction (Switch Ver) | 5,188 | Let's Play |
| 49. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S2 P1 | 5,187 | Let's Play |
| 50. | Zorrin小崎 | Margaret & Alice is so... Sublime! | NMH2 Desperate Struggle Ep.4 Lets Play/Reaction (Switch Ver) | 5,115 | Let's Play |
| 51. | Zorrin小崎 | Travis vs Henry! Fake and Real Ending! | No More Heroes Ep. Finale Lets Play & Reaction (Switch Ver) | 5,109 | Let's Play |
| 52. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #2 - For Bishop!!! | 4,908 | Let's Play |
| 53. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S3 | 4,817 | Let's Play |
| 54. |  iNEXXXUS | No More Heroes 2: Desperate Struggle on Dolphin Wii/GC Emulator (720p HD) Full Speed | 4,812 | Let's Play |
| 55. | Turner459O | Let's Play No More Heroes 2 - Part 3 - Bugbusters | 4,623 | Let's Play |
| 56. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S4 P1 | 4,540 | Let's Play |
| 57. | Zorrin小崎 | It's been so long! Dr. Letz Shake is Back! | NMH2 Desperate Struggle Ep2 Lets Play/Reaction (Switch) | 4,519 | Let's Play |
| 58. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S7 - Pervy Teacher | 4,473 | Let's Play |
| 59. | MuzikB0x | Let's Play No More Heroes 2 : Desperate Struggle FR - Ep 1 - "Gelée Bizarre 5"... hum hum ! | 4,344 | Let's Play |
| 60. | Turner459O | Let's Play No More Heroes 2 - Part 6 - LB Dollar Powah! | 4,247 | Let's Play |
| 61. | Turner459O | Let's Play No More Heroes 2 - Part 7 - Rank 50 ~ Nathan Copeland | 4,222 | Let's Play |
| 62. | Zorrin小崎 | This Final Boss is Frustrating!!! | NMH2 Desperate Struggle Finale Lets Play/Reaction (Switch Ver) | 4,179 | Let's Play |
| 63. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S5 P2 | 4,077 | Let's Play |
| 64. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S4 P2 | 4,077 | Let's Play |
| 65. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S5 P1 | 4,047 | Let's Play |
| 66. | Turner459O | Let's Play No More Heroes 2 - Part 33 - Rank 2 ~ Alice Twilight | 4,032 | Let's Play |
| 67. | Turner459O | Let's Play No More Heroes 2 - Part 10 - Rank 49 - 25 ~ Charlie MacDonald & His Hoes | 3,979 | Let's Play |
| 68. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #8 - Super Awesome Robot Battle! | 3,976 | Let's Play |
| 69. | Turner459O | Let's Play No More Heroes 2 - Part 4 - Plumber's Don't Wear Red Jackets | 3,970 | Let's Play |
| 70. | Turner459O | Let's Play No More Heroes 2 - Part 15 - Rank Defense ~ Kimmy Howell | 3,921 | Let's Play |
| 71. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #3 - Retro-Style Money Grinding | 3,894 | Let's Play |
| 72. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #4 - A Fabulous Workout | 3,875 | Let's Play |
| 73. | Turner459O | Let's Play No More Heroes 2 - Part 29 - Rank 4 ~ Margaret Moonlight | 3,862 | Let's Play |
| 74. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S6 P2 | 3,826 | Let's Play |
| 75. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S6 P1 | 3,771 | Let's Play |
| 76. | Turner459O | Let's Play No More Heroes 2 - Part 17 - Rank 23 ~ Cloe Walsh | 3,749 | Let's Play |
| 77. | Your Pal, Ral! | No More Heroes 2: Desperate Struggle (Blind) - Episode 1 "Return To Santa Destroy" | 3,714 | Let's Play |
| 78. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #5 - Rap Battle | 3,696 | Let's Play |
| 79. | Turner459O | Let's Play No More Heroes 2 - Part 13 - Rank 24 ~ Matt Helms | 3,679 | Let's Play |
| 80. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S8 | 3,531 | Let's Play |
| 81. | Turner459O | Let's Play No More Heroes 2 - Part 23 - Rank 8 ~ New Destroyman | 3,365 | Let's Play |
| 82. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #27 - Vengeance | 3,243 | Let's Play |
| 83. | Turner459O | Let's Play No More Heroes 2 - Part 19 - Rank 10 ~ Dr. Letz Shake | 3,110 | Let's Play |
| 84. | rabbid2igi | HIGHLIGHTS: Let's Play No More Heroes 2: Desperate Struggle | 3,044 | Let's Play |
| 85. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #6 - Fuzzy Nuts and Oily Surfaces | 3,043 | Let's Play |
| 86. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S9 P1 | 3,003 | Let's Play |
| 87. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #18 - Dawn of the Samurai | 2,916 | Let's Play |
| 88. | Turner459O | Let's Play No More Heroes 2 - Part 37 - My No More Hero (Finale) | 2,905 | Let's Play |
| 89. | Turner459O | Let's Play No More Heroes 2 - Part 30 - Rank 3 ~ Captain Vladimir | 2,879 | Let's Play |
| 90. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S9 P2 | 2,865 | Let's Play |
| 91. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S11 | 2,862 | Let's Play |
| 92. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S10 P1 | 2,846 | Let's Play |
| 93. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S12 P1 - The End | 2,844 | Let's Play |
| 94. | Helloween4545 | Let's Play No More Heroes 2: Desperate Struggle - S12 P2 - The End | 2,818 | Let's Play |
| 95. | Turner459O | Let's Play No More Heroes 2 - Part 11 - Meat Boy | 2,804 | Let's Play |
| 96. | Turner459O | Let's Play No More Heroes 2 - Part 26 - Mimmy In The Sky With Diamonds | 2,763 | Let's Play |
| 97. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #11 - Behead the Undead | 2,728 | Let's Play |
| 98. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #17 - A Blast from the Past | 2,688 | Let's Play |
| 99. | Turner459O | Let's Play No More Heroes 2 - Part 21 - Rank 9 ~ Million Gunman | 2,682 | Let's Play |
| 100. | GeneralSecura | Let's Play No More Heroes 2: Desperate Struggle #13 - A Fan with a Plan | 2,672 | Let's Play |
