| 1. |  Gar | 56,858 | Painkiller (Commentary) Level 5-4: Hell | 19:40 |
| 2. | Zelgadis115 | 55,093 | Let's Play Painkiller: Black Edition (Nightmare) Ch5L4 Hell | 22:48 |
| 3. |  LGR | 45,362 | LGR Plays - Painkiller HD | 17:39 |
| 4. | GHostLPs | 43,346 | Painkiller: Black Edition - 34 Alastor (Round 3) | 13:38 |
| 5. | BizarrelyFunny | 18,316 | Scorpion & Smoke Play - PAINKILLER | MK9 GAMEPLAY PARODY! | 9:30 |
| 6. | JarekTheGamingDragon | 11,495 | Let's Play Painkiller HD Coop: Colosseum | 34:22 |
| 7. | Wickman Wish | 8,241 | Let's Play Painkiller: Black Edition - (C6L10) Shadowland | 10:29 |
| 8. | Gameplay and Talk | 7,565 | Painkiller - Full Trauma Playthrough (PC, Steam) | Gameplay and Talk Live Stream #467 | 4:58:05 |
| 9. |  Gurthang | 5,630 | Painkiller Lost Alpha(DC) #28 Kraina Cieni + Epilog! | 6:59 |
| 10. |  BiohazardJokerCZ | 5,580 | Český Let's Play Painkiller | Part 32 - Král Alastor | 12:54 |
| 11. | Корвус | 4,934 | Brutal Let's Play "Painkiller" by KORVUS | 10:54 |
| 12. | Starcrossed Souls - Zoids | 4,438 | Let's play Painkiller: Hell Wars (xbox) part 9 | 8:32 |
| 13. | K0DeX | 4,012 | Let's play Painkiller Overdose PART 8B | 3:48 |
| 14. | Double Negative | 3,798 | Part 33: Shadows of Fate - Let's Play Painkiller | 13:00 |
| 15. | ArachCobra | 1,720 | Let's Play Painkiller Blind Part 44 | 8:52 |
| 16. | Burning Fish Gaming | 1,710 | Painkiller: Alpha Gameplay | 14:34 |
| 17. |  RalFinger | 1,680 | Let´s Play Painkiller HD #014 - Ärger mit dem Typen braucht doch keiner? | 17:44 |
| 18. |  AyorSaeba | 1,226 | [Rediff][Let's Play] Painkiller (PC)(Part 5/5) | 1:35:05 |
| 19. | KrayzieeGaming | 1,181 | Krayziee plays Painkiller | Chapter 5 | Level 4 Hell FINAL Boss | 7:12 |
| 20. | JacksawJack | 1,025 | Let's Play Painkiller (C5L4) | 9:19 |
| 21. | Cubeface | 1,005 | Painkiller playthrough -- Part 5 | 1:14:43 |
| 22. |  Terry 309 | 969 | Let's Play Painkiller Battle Out Of Hell: BONUS: Loony Park Alternative Route (Out Of Loony Park) | 7:47 |
| 23. | Quick | 699 | LUCIFER A HODNOCENÍ! | Painkiller: Black Edition | Painkiller #10 | Let'sPlay CZ/Česky [1080p] [PC] | 38:35 |
| 24. | LittleDwarf | 681 | Making of Painkiller - Dev Video | 19:32 |
| 25. | Rik's Random Retro | 599 | Livestream - Mystery Card ft PixelPipes and Sucra | 4:09:13 |
| 26. |  Gameplays TV | 597 | Hambo: Mission 2 - Level 01-10 Code Name Painkiller - Gameplay | 6:08 |
| 27. |  TheHuNNo | 527 | Let's play Good old games: Painkiller Battle Out of Hell Part 9 | 22:47 |
| 28. | Van FirleFranz | 517 | Painkiller Part 16 Let's Play German, Deutsch | 34:59 |
| 29. |  pirania_games | 514 | Каменная яма | Painkiller: NecroGenesys | Битва за пределами ада #9 [Let's Play] | 32:31 |
| 30. |  SamMcKdamn | 500 | Let's Play Painkiller World 5-4 | 18:37 |
| 31. | Phantassm | 411 | Unfinished Playthroughs #2 - 3 of 3 Segment Recorded (Originally Recorded - 04.03.2011) | 32:12 |
| 32. | acidonia150 | 400 | Let's play Painkiller Black Edition part 9 cho cho woo woo tomas | 21:53 |
| 33. | Ronteckx | 398 | monster ärgern ab 18+ :D Live | Painkiller | 1:30:43 |
| 34. | VGamingJunkieVT | 392 | Let's Play Painkiller [Finale] - Power on Through! The End of Lucifer!? | 27:11 |
| 35. | EdgeCrusher140 | 389 | Painkiller Lost Alpha - Colosseum | 5:49 |
| 36. | AlbatrossofTime | 379 | AlbatrossofTime's Let's Play: Painkiller Black Edition TRAUMA 20 | 1:28:45 |
| 37. | Our Gutless Life | 352 | Painkiller: Chapter 3/Level 3: J Plays Solo | 28:44 |
| 38. | Dark Mercer Gaming | 352 | PainKiller Trauma Playthrough Chapter 4 Levels 4 and 5-Forest and Tower | 6:41 |
| 39. | Kirill Apollyon | 335 | Painkiller - 2 level, Atrium Complex, Nightmare playthrough. Max settings(60 fps). All secrets | 13:41 |
| 40. | havi LP | 320 | Let's Play Painkiller [DEUTSCH] [HD] #015 - Biker in einer Wasserstadt?? | 25:59 |
| 41. | Angel Dust | 258 | 18+ Painkiller Black Edition Кровавая игра. Конец первой части из пяти! | 2:40:50 |
| 42. |  Dan Johansen | 245 | Strit Plays On Linux #6: Painkiller - Hell And Damnation | 20:27 |
| 43. | Tribes21 | 226 | Painkiller Let's play - Episode 1(part2) L'orphelinat | 15:52 |
| 44. |  vinnichanin | 214 | #PAINKILLER | ЧАСТЬ 4. ЗАМОК | Quad HD | 1440p | 2:20:11 |
| 45. | Purgatory Corner | 179 | Painkiller #17 (Finale) | Sin Plays | Literally Down In Hell! | 18:44 |
| 46. | VideoGames | 156 | Painkiller - Daniels Ordeal / LETS PLAY | 26:01 |
| 47. | TheFanarnarChannel | 134 | Let's Play Painkiller Part 3 - FanarnarBoi - MAXIMUM STEAKS | 13:42 |
| 48. | Marquis Forneus | 131 | Lets Play: Painkiller | Part 7 | 30:20 |
| 49. | Game Wisdom | 118 | Classic Game Stream -- Painkiller Black | 1:00:15 |
| 50. | MattPlayful | 116 | ZCHÁTRALÝ KLÁŠTER | Painkiller: Black Edition | #21 | CZ Let's Play | 20:33 |
| 51. |  PalpySeb's Archive | 97 | Painkiller Black Edition let's play | part 2.5 | 1:46:17 |
| 52. | Nick Jaime | 71 | Painkiller Resurrection story mode Playthrough 1080p GTX 980 SLI PC | 32:40 |
| 53. |  The Faceless Strategist | 68 | Painkiller Black Edition Chapter 5, Level 3 Old Monastery Playthrough | 19:05 |
| 54. |  Playthrough Emporium | 68 | Painkiller - Full Game Playthrough | Longplay - PC - HD [Insomnia] | 4:38:24 |
| 55. | h00ch2003 | 65 | Painkiller: Black Edition - Battle out of Hell (Part 2) playthrough | 1:55:35 |
| 56. | SwetCZ stream záznamy | 59 | Painkiller: Hell & Domnation |Kompletní průchod| CO-OP | CZ stream záznam | | 4:17:10 |
| 57. | ChozoWarrior1 gaming | 56 | Let's play painkiller hell wars XBOX pt2 | 16:22 |
| 58. | IndieTimmie | 51 | IT'S A WEAPON - Painkiller (Ep.1) | 24:28 |
| 59. |  Arjan Nuts Gaming | 47 | Let's play #witchfire a game by the developers of #painkiller | 0:59 |
| 60. | TheAEStudios | 45 | Painkiller Playthrough pt:3 I Don't want your bibles | 13:22 |
| 61. | KeepCalmAndGameOn | 44 | Adam Plays: Painkiller | 41:56 |
| 62. |  Masky | 34 | A Tough Boss Battle Painkiller-Part 2-Gameplay/Playthrough/First Person Shooter | 33:33 |
| 63. | neXGam | 32 | neXGam plays Painkiller Part 1 (PC) | 1:58:52 |
| 64. |  RealAlex | 30 | Let's play Painkiller - part 2 | 52:30 |
| 65. |  مصطفى الزوايدي لعلوم الحاسب | 24 | painkiller blackedition episode 38 gameplay | 22:21 |
| 66. |  TheDark WolfBUL | 14 | Dark Plays: Painkiller, Ep.1: #UglyDemonShaming | 49:08 |
| 67. | Cylon LP | 8 | Let´s Game - Painkiller 1 (Black Edition /German ) #10 - Im Bahnhof der Untoten 👻👽😱 | 43:35 |
