| 1. |  The Yogscast | 2,974,024 | Yogscast - Simon Plays! - Portal 2, 5: The Honeydew Defense | 15:03 |
| 2. | Harry101UK | 1,771,239 | Harry Plays - Portal Reloaded | My brain hurts | 1:34:35 |
| 3. | mashed | 722,773 | Portal: Betty Help? | 4:36 |
| 4. | Encrypted Duck | 509,636 | Portal 2 - Full Co-Op Story (No Commentary) | 2:44:59 |
| 5. | PixelTwitch | PC Gaming Goodness | 484,494 | Let's Play! - Portal Stories: MEL - Part 14 - Confusing... | 25:15 |
| 6. | Outside Xtra | 296,957 | NPCs Who Are So Done With Your Bulls*** | Commenter Edition | 16:59 |
| 7. | PlayStation Access | 229,265 | PlayStation Trophies We're Embarrassed To Have Earned | 14:36 |
| 8. | OfficialNerdCubed | 215,849 | Nerd³ Plays... The Nest VR - The Droids You're Looking For | 13:38 |
| 9. | MiniminterClips | 160,666 | GRAVITY CONFUSED US! Miniminter x Randolph Part 3 (Portal 2) | 1:13:14 |
| 10. | Charlotte & Zeke | 74,474 | You Saved Science! The Human Vault | Portal 2 CO-OP EPISODE 12 | 38:35 |
| 11. | Circuit The World | 63,067 | Finding Real Humans?? | Let's Play: Portal 2 - Co Op #5 (with @Livvy5411) | 1:08:25 |
| 12. | Sips - Live! | 61,376 | Sips Beats Portal 2 - (20/12/19) | 3:34:17 |
| 13. | ibxtoycat | 48,919 | Portal 2 Playthrough Final - I ONLY WANT YOU GONE | 1:41:31 |
| 14. | Rocky Rockhead | 46,301 | I Have Ascended!! - PORTAL RELOADED | Let's Play - ENDING | 1:08:47 |
| 15. | PURE PSX | 23,602 | PlayStation Portal 2 NEEDS to be Better – Here's How! | 15:53 |
| 16. | Broughy's Random Bits, Let's Plays & Streams | 23,396 | Portal 2 - Chapter 9: The Part Where He Kills You - Playthrough/Let's Play | 27:56 |
| 17. | MiniminterExtra | 22,381 | PORTAL 2 WITH RANDOLPH (FULL VOD) | 2:55:41 |
| 18. | Lextube | 21,177 | Thinking with Time Machine (Portal 2) #5 - Lex Plays | 9:20 |
| 19. | Let's Play Gaming! - SheepNDane | 16,417 | Let's Play Portal 2 - Part 7 - "What does this do.. OOOH shizzle!" | 10:46 |
| 20. | Neo Rambler | 13,193 | Let's Play Portal 2 Blind (PC): The End | 50:01 |
| 21. | DazzReviews2 | 12,331 | Portal 2 - Bonus 3 - Rattmann | 9:31 |
| 22. | NOCK | 11,340 | Greasiest Doorknob (Part 4) | Community Maps Livestream (2021-07-14) | 28:43 |
| 23. | derangedband | 7,329 | Lets Play Portal 2 Part 7 FINALE | 28:44 |
| 24. | Twisted Inc | 6,614 | Portal 2 │ Singleplayer Campaign │ Part 14 (Final) │ "Want You Gone" | 31:31 |
| 25. | Knightenator | 6,105 | Getting killed over and over in Portal 2 - FIRST PLAYTHROUGH EVER // Knightenator ft. Mark | 40:10 |
| 26. | The CaffCast | 3,815 | CaffCast & PixelTwitch Play - Portal 2 - Co-Op Mode - Part 7 - Doing It Wrong? | 33:17 |
| 27. | TheSageRises | 3,574 | Co-op Let's Play Portal 2 - Part 13 [HD] | 13:09 |
| 28. | PartContinuum | 3,528 | Portal 2: REAL LIFE PORTAL FOR THE TOILET | 10:43 |
| 29. | Viexi | 3,371 | Let's Play: Portal 2 - Part 35 - Aristotle vs. MASHY SPIKE PLATE (1080p) | 10:16 |
| 30. | Dragonster16 | 2,898 | Let's Play Portal 2 part 18 | 18:15 |
| 31. | DannyEddy357 | 2,524 | Let's Play: Portal 2 Co-Op #26 | 9:25 |
| 32. | TheMaster974 | 2,303 | Gareth Plays: Portal: Revolution Part 6 (Pneumatic Diversity Vent Testing!) | 26:22 |
| 33. | Stybb Gaming | 2,267 | Let's Play Portal 2 Episdode 8!: Wheatley labs hell | 1:27:05 |
| 34. | Utorak007 | 2,202 | Portal 2 Playthrough w/ Utorak PC HD Part 2 | 10:30 |
| 35. | Whiffen | 2,167 | Jamie's Epic Portal 2 Lets Play! Episode 001 ~ Wheatley NO! | 11:09 |
| 36. | Linx | 2,007 | The Betrayal | Portal 2 playthrough - Part 3 | 33:31 |
| 37. | Salford Sal | 1,947 | S09E8 Sal Plays Portal2 - with MereLyap - Bouncing Cubes | 23:21 |
| 38. | redhotsonic | 1,945 | Let's Play Portal 2 - LIVE - Part 2 - Sunday 26th February '17 8pm GMT | 3:03:46 |
| 39. | jpbrawler2 | 1,886 | Let's Play Portal 2 - Multiplayer Part 1 [Re-uploaded] | 8:12 |
| 40. | FxGamerOfficial | 1,865 | YOU GIVE ME HEART PALPATIONS DAN! | Portal 2 Co-op Part 5 | 39:42 |
| 41. | DarkHoodness | 1,722 | Portal 2 PeTI - "Platforms" by Nepsotic - Community Map Playthrough | 5:24 |
| 42. | MegFromTheWeb | 1,617 | Meg Plays Portal 2 - Episode 14 | 21:05 |
| 43. | ReformistTM | 1,556 | Let's Play Portal 2 - Part 21 Final - Walkthrough | 7:10 |
| 44. | HellfireComms | 1,491 | Portal (2024) playthrough [Part 3: Ghost and the Chell] *FINALE* | 35:21 |
| 45. | Tangociss | 1,322 | Tangociss Plays! Portal 2! Episode 20! A Nice Little Chamber | 3:51 |
| 46. | UndulateOak | 1,261 | Portal 2 Co-op - Ending Ft. Mogdread "Full Circle" | 25:19 |
| 47. | Matt and Gus | 1,220 | Gus plays - Portal *Science is a Headache!* | 14:44 |
| 48. | Tom plays games! | 1,045 | Tom plays... Portal 2 (Ep 23) | 1:00:38 |
| 49. | UZB GAMING | 993 | PORTAL ► OSON EMAS #2 ► UZBEKCHA LETSPLAY | 25:58 |
| 50. | TripleJump VODs | 988 | PUZZLES MAKE MY BRAIN GO BRRR! - Portal 2 [Part 2] | TripleJump Live! | 2:02:55 |
| 51. | Luke Starkiller Gaming Videos | 987 | Portal Stories: Mel Chapter Five: Intrusion Playthrough 2K 60FPS | 28:34 |
| 52. | FillNill | 923 | Let's Play Portal 2: Part Six "Trash, standing around. Smelling and being useless"! | 13:28 |
| 53. | MitchCyan | 771 | my portal 2 playthrough pt 67 (final) | 3:57 |
| 54. | HiMyNameIsEdson | 636 | Let's Play Portal 2 Co-Op w/ Eneija #10 (FINALE) | HURTS MAH BRAIN | 29:23 |
| 55. | Sorceror Nobody | 608 | Nobody Plays Portal Ep. 38: Uncooperative Testing Initiative | 35:06 |
| 56. | PCGamingXI | 607 | Let's Play Portal 2 Ep13: Goodbye GLaDOS :'( | 24:56 |
| 57. | Crazy4Games | 595 | Let's Play Portal 2 - Part 4 - The surprise is a lie | 23:30 |
| 58. | Platform32 | 593 | Portal 2 - Eric Wolpaw Interview - Platform32 | 5:55 |
| 59. | SquadB Gaming | 568 | 2013 Squad B Advent Calender - Day 6 - Pyrex Plays Portal Poorly - PPPP | 17:00 |
| 60. | Alpaka Whacker | 550 | "Portal 2" Livestream (with AlpakaWhacker) - Part 2 | 13:40 |
| 61. | JDragon56 | 541 | Let's Co-op Portal 2 - 06b - The Vault Door Looms... | 13:40 |
| 62. | Masterath Gaming | 528 | Let's Play Portal 2 part 19/19: Wheatley Goes to Space, I Go Home | 21:38 |
| 63. | Elanip | 526 | Elanip Play's Portal 2: Part 1 - I'm so Good at This Game | 13:58 |
| 64. | Darkstar263 | 465 | Portal 2 (PS3) Playthrough: Final Boss, Ending and Credits | 13:42 |
| 65. | Gar1onriva | 464 | Co-oP Portal 2 [Part 23] Air Skills | 12:16 |
| 66. | PureChaosX | 451 | Portal 2 - Part 7 (Final) | 33:32 |
| 67. | Genie | 438 | Genie Plays Portal 2 - Episode 10 | 10:05 |
| 68. | God is a Geek | 431 | LEGO Dimensions: Let's play the Portal 2 Level Pack | 10:23 |
| 69. | BaamGames | 422 | Two men go into each others holes...! | Portal 2 Live | 2:09:34 |
| 70. | ItZoTom | 389 | Portal 2 Custom Map Let's Play #016 The End Of 12 Angry Tests! | 10:17 |
| 71. | _poppyplays_ | 388 | Poppy Plays Portal 2 Co-Op Mode with her husband #4 | ft. @CryoNoir | 2:29:42 |
| 72. | iGame | 388 | Portal 2 SP Gameplay/Playthrough Part 17 "The ,End" | 18:01 |
| 73. | Mischief of Mice | 384 | Mischief Musings: See You On The Other Side (Portal-like puzzler) | 16:11 |
| 74. | ScottyDGaming | 368 | Portal 2 / Full Game with Commentary / Complete Blind Longplay Playthrough | 5:46:48 |
| 75. | TheDJBuntin | 360 | Portal 2 - Playthrough - Part 2 "The Basics" By Cirai2tna | 5:45 |
| 76. | windows xpnt | 351 | xpnt live | portal 2 full play through live | 3:11:57 |
| 77. | The Gaming Ghoul | 351 | Let's Play Portal 2 Finale - SPAAACE!!! | 22:44 |
| 78. | SuperCJK333 | 329 | Let's Play Portal 2 CO-OP: Part 26 (Downloadable Levels) | 9:51 |
| 79. | Retro Football | 325 | Let's Play Portal! - Part 04 - Famous Last Words: "They're so cute!" | 7:02 |
| 80. | Scarbeus | 324 | Portal 2 Let's Play - Gameplay Episode 20: The Final Test | 18:16 |
| 81. | Laughable walkthroughs | 305 | Portal 2 Playthrough - The END!!! - Ep9 | 30:33 |
| 82. | Poog | 304 | Lets Play - Portal 2 (Part 3) | 13:53 |
| 83. | Miss Meggiecat | 295 | BLASTING OFF AGAIN! | Portal 2 #14 (FINALE) | 23:32 |
| 84. | DefendingTheGame | 294 | Portal 2 CO-OP Blind Playthrough | "Porkle" | Part 3 - Defending The Game | 12:11 |
| 85. | EarthToLydia | 290 | BUTTONS, LASERS, AND THROWING STUFF!! | Let's play PORTAL 2: Part 5 (with HOTHEMAN) | 24:26 |
| 86. | MizuhoChan | 288 | Let's Play Portal 2 In 3D - Part 2 - The Revival (Stereoscopic) | 16:21 |
| 87. | daddyhughes111 | 281 | Friends Play...Portal 2 - Level 5 Co-op #5 w/Killerblob4 (PC 60fps Gameplay Let's Play Review) | 26:11 |
| 88. | Rusty Dog | 270 | Rusty Plays: Portal & Portal 2 | 2:57:41 |
| 89. | JoshBeGaming | 261 | Let's Play: Portal 2 | Episode 14 - Finale! | 23:38 |
| 90. | That Ifrit Guy | 258 | Let's Play Portal 2 - 11 - Want you Gone | 30:24 |
| 91. | GTArajgaming | 255 | LET'S PORTAL IT UP!! GTAraj plays portal stories MELS | 2:44:01 |
| 92. | HoshiShang | 231 | Let's Play!: Portal 2 with Mythie [PART 9, FINAL] | 24:16 |
| 93. | DreamRJ | 223 | LETS PLAY: Portal Mod - Rexaura Part 4 - Mod By Mevious | 41:37 |
| 94. | Mr. Nutt | 220 | Let's Play: Portal 2 Part 7 | 26:57 |
| 95. | Jackasaurus | 208 | Lets Play Portal 2 Co-OP Part 8 W/ Fussko | 22:26 |
| 96. | Roasdkill | 199 | Roasdkill Plays Portal 2 -'The End'' ~PART 19~ | 13:48 |
| 97. | JohnTMorton | 199 | Nostalgamer Unboxes Portal 2 Two On Sony Playstation 3 Three UK PAL System Version | 1:21 |
| 98. | PixelBytes | 198 | Lets Play: Portal 2 Episode 4 | 19:11 |
| 99. | backofficeshow | 181 | Longplay - Portal 2 Complete Playthrough! | 6:23:26 |
| 100. | Lex Ellis | 179 | Lex Plays - PORTAL - Part 4 (ENDING) | 12:05 |
