| 1. |  VGS - Video Game Sophistry | Psychonauts 2 - Jack Black Sings as The PSI KING // Full Music Video | 382,915 | |
| 2. | Jaba Play | Psychonauts 2 - All Bosses + Ending | 378,394 | |
| 3. | Nitro Rad | Psychonauts 2 - Nitro Rad | 267,771 | |
| 4. | ★WishingTikal★ | Psychonauts 2 FULL GAME 100% Longplay (PS4, XBOX ONE, PC) | 82,609 | Walkthrough |
| 5. | GamersPrey | Psychonauts 2 - Full Gameplay Walkthrough [4K] | 80,501 | Walkthrough |
| 6. | yp | [WR] Psychonauts Speedrun in 30:53 | 58,189 | |
| 7. | VGS - Video Game Sophistry | Psychonauts 2 - Raz and Lili Full Romance // All Scenes | 48,767 | |
| 8. | VGS - Video Game Sophistry | Psychonauts 2 - All Bosses/Boss Fights + Full Ending | 36,559 | |
| 9. | Welonz | Psychonauts 2 Let's Play Part 1 - 16 Years Later, Raz's Adventures Continue! [Blind PC Gameplay] | 30,919 | Let's Play |
| 10. | GamersPrey | Psychonauts 2 Jack Black Trailer [HD 1080P] | 29,145 | Preview |
| 11. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 1 (XB1, PS4, PC) 100% | 19,616 | Walkthrough |
| 12. | VGS - Video Game Sophistry | Psychonauts 2 - ENDING + Maligula Final Boss Fight | 18,703 | |
| 13. | Welonz | The New Intern - Psychonauts 2 Let's Play Part 2 [Blind PC Gameplay] | 15,748 | Let's Play |
| 14. | VGS - Video Game Sophistry | Psychonauts 2 - Raz Saves and Reunites All the Psychonauts | 15,741 | |
| 15. | The NyanCave | 【 THE GAME AWARDS 】Game of The Year is.... | 13,307 | |
| 16. | Rubhen925 | Psychonauts 2 - Gameplay Walkthrough Part 1 | Xbox Series X Preview (4K 60FPS) | 13,173 | Walkthrough |
| 17. | Welonz | The Mind of Agent Forsythe - Psychonauts 2 Let's Play Part 3 [Blind PC Gameplay] | 12,908 | Let's Play |
| 18. | Welonz | A Broken Heart - Psychonauts 2 Let's Play Part 4 [Blind PC Gameplay] | 12,116 | Let's Play |
| 19. | Welonz | Truman's Secret Mission - Psychonauts 2 Let's Play Part 7 [Blind PC Gameplay] | 11,848 | Let's Play |
| 20. | VGS - Video Game Sophistry | Psychonauts 2 - Raz Meets His Family and They Team Up | 11,680 | |
| 21. | Welonz | Lovers' Quarrel - Psychonauts 2 Let's Play Part 6 [Blind PC Gameplay] | 11,637 | Let's Play |
| 22. | Welonz | Compton's Cookoff - Psychonauts 2 Let's Play Part 11 [Blind PC Gameplay] | 11,630 | Let's Play |
| 23. | Welonz | Family Disputes - Psychonauts 2 Let's Play Part 8 [Blind PC Gameplay] | 11,602 | Let's Play |
| 24. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 2 (XB1, PS4, PC) 100% | 11,386 | Walkthrough |
| 25. | Cannot be Tamed | Blade Runner, Psychonauts 2, Big Con, Airport Dog game and more September updates | Cannot be Tamed | 11,315 | Vlog |
| 26. | Welonz | Lady Luctopus in the House - Psychonauts 2 Let's Play Part 5 [Blind PC Gameplay] | 11,311 | Let's Play |
| 27. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 5 (XB1, PS4, PC) 100% | 10,754 | Walkthrough |
| 28. | Welonz | Feast of the Senses - Psychonauts 2 Let's Play Part 14 [Blind PC Gameplay] | 10,502 | Let's Play |
| 29. | Welonz | Sensory Overload - Psychonauts 2 Let's Play Part 13 [Blind PC Gameplay] | 10,420 | Let's Play |
| 30. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 4 (XB1, PS4, PC) 100% | 10,231 | Walkthrough |
| 31. | Welonz | Fatherland Follies - Psychonauts 2 Let's Play Part 26 [Blind PC Gameplay] | 10,189 | Let's Play |
| 32. | Welonz | Green Needle Witch - Psychonauts 2 Let's Play Part 9 [Blind PC Gameplay] | 10,039 | Let's Play |
| 33. | Welonz | Otto Mentallis - Psychonauts 2 Let's Play Part 10 [Blind PC Gameplay] | 9,877 | Let's Play |
| 34. | Welonz | The Truth About Maligula - Psychonauts 2 Let's Play Part 18 [Blind PC Gameplay] | 9,711 | Let's Play |
| 35. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 6 (XB1, PS4, PC) 100% | 9,659 | Walkthrough |
| 36. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 3 (XB1, PS4, PC) 100% | 9,362 | Walkthrough |
| 37. | Welonz | Ford's Follicles - Psychonauts 2 Let's Play Part 12 [Blind PC Gameplay] | 9,304 | Let's Play |
| 38. | Welonz | Cassie's Collection - Psychonauts 2 Let's Play Part 19 [Blind PC Gameplay] | 9,239 | Let's Play |
| 39. | VGS - Video Game Sophistry | Psychonauts 2 - All Memory Vault Locations + All Character Lore | 9,175 | |
| 40. | TetraNinja | PSYCHONAUTS 2 GAMEPLAY TRAILER E3 2019 | 9,034 | Preview |
| 41. | Welonz | Bob's Bottles - Psychonauts 2 Let's Play Part 22 [Blind PC Gameplay] | 8,982 | Let's Play |
| 42. | Welonz | Memories of the Past - Psychonauts 2 Let's Play Part 23 [Blind PC Gameplay] | 8,899 | Let's Play |
| 43. | Welonz | Mail Lost and Found - Psychonauts 2 Let's Play Part 15 [Blind PC Gameplay] | 8,730 | Let's Play |
| 44. | GamersPrey | Psychonauts 2 - Ending and Final Boss [4K] | 8,597 | |
| 45. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 8 (XB1, PS4, PC) 100% | 8,539 | Walkthrough |
| 46. | Welonz | The Deluge of Grulovia - Psychonauts 2 Let's Play Part 27 Main Story Ending [Blind PC Gameplay] | 8,452 | Let's Play |
| 47. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 7 (XB1, PS4, PC) 100% | 8,291 | Walkthrough |
| 48. | Welonz | Lili's Rare Fungus - Psychonauts 2 Let's Play Part 16 [Blind PC Gameplay] | 8,049 | Let's Play |
| 49. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 9 (XB1, PS4, PC) 100% | 8,003 | Walkthrough |
| 50. | Welonz | Lucrecia's Lament - Psychonauts 2 Let's Play Part 25 [Blind PC Gameplay] | 7,964 | Let's Play |
| 51. | Welonz | Bowling in Germ City - Psychonauts 2 Let's Play Part 17 [Blind PC Gameplay] | 7,916 | Let's Play |
| 52. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 10 (XB1, PS4, PC) 100% | 7,881 | Walkthrough |
| 53. | Welonz | 100% Completion (Post Game) - Psychonauts 2 Let's Play Part 29 Ending [Blind PC Gameplay] | 7,638 | Let's Play |
| 54. | Welonz | Literature Lane - Psychonauts 2 Let's Play Part 20 [Blind PC Gameplay] | 7,509 | Let's Play |
| 55. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 11 (XB1, PS4, PC) 100% | 7,103 | Walkthrough |
| 56. | Welonz | Revisiting Old Mental Worlds - Psychonauts 2 Let's Play Part 24 [Blind PC Gameplay] | 7,032 | Let's Play |
| 57. | Welonz | Extra Credit (Post-Game) - Psychonauts 2 Let's Play Part 28 [Blind PC Gameplay] | 7,019 | Let's Play |
| 58. | Welonz | The Die-brarian - Psychonauts 2 Let's Play Part 21 [Blind PC Gameplay] | 6,897 | Let's Play |
| 59. | The NyanCave | 【 PSYCHONAUTS 2 】Part 1 | Game of the Year? | Blind Gameplay Live Reaction | 6,880 | |
| 60. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 13 (XB1, PS4, PC) 100% | 6,736 | Walkthrough |
| 61. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 14 (XB1, PS4, PC) 100% | 6,686 | Walkthrough |
| 62. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 12 (XB1, PS4, PC) 100% | 6,675 | Walkthrough |
| 63. | VGS - Video Game Sophistry | Psychonauts 2 - Ford Reveals the Truth About Raz's Grandmother // Secret Love | 6,536 | |
| 64. | VGS - Video Game Sophistry | Psychonauts 2 - Raz Saves His Grandmother and Becomes a Psychonaut | 6,472 | |
| 65. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 17 (XB1, PS4, PC) Ending + Post Game 100% | 6,458 | Walkthrough |
| 66. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 15 (XB1, PS4, PC) 100% | 6,439 | Walkthrough |
| 67. | ★WishingTikal★ | Psychonauts 2 Walkthrough Part 16 (XB1, PS4, PC) 100% | 6,261 | Walkthrough |
| 68. | Bacxaber | Psychonauts 2 be like | 6,156 | |
| 69. | KOFI | Press Start Podcast Episode 202 | Psychonauts 2 vs HypeBeast Gamers | 5,881 | |
| 70. | Rubhen925 | Psychonauts 2 - Walkthrough Gameplay Part 1 (Xbox Series X) | 5,596 | Walkthrough |
| 71. | VGS - Video Game Sophistry | Psychonauts 2 - Talking to All Major Characters After Beating the Game // Post Game | 5,470 | |
| 72. | ★WishingTikal★ | Psychonauts 2 All Bosses (PS4, XB1, PC) | 5,272 | Walkthrough |
| 73. | The NyanCave | 【 THE GAME AWARDS 2021 】 Voting + Nominees | Predicting winners LIVE Reaction (100% success rate) | 5,066 | |
| 74. | Rubhen925 | Psychonauts 2 - All Boss Fights | XSX Preview Gameplay (4K 60FPS) | 4,955 | Preview |
| 75. | Zoomg I زومجی | بازی سایکوناتز ۲ | ماجراجویی در مدرسه اَبَر فسقلی ها - زومجی | 4,587 | |
| 76. | None | Did You Notice This In Psychonauts 2? | 4,496 | |
| 77. | The NyanCave | 【 PSYCHONAUTS 2 】Mind Break | Part 2 | New Connections | Blind Gameplay Live Reaction | 4,487 | |
| 78. | Rubhen925 | Psychonauts 2 - Cassie's Collection Level Gameplay | Xbox Series X Preview (4K 60FPS) | 4,088 | Preview |
| 79. | Rubhen925 | Psychonauts 2 - Compton's Cookoff Level Gameplay | Xbox Series X Preview (4K 60FPS) | 3,841 | Preview |
| 80. | The NyanCave | 【 PSYCHONAUTS 2 】Daddy Disappointment | Part 3 | Blind Gameplay Live Reaction | 3,673 | |
| 81. | Badman Reviews | Psychonauts 2 - First Impressions - Badman | 3,577 | First Impressions |
| 82. | GamersPrey | Psychonauts 2 - E3 2019 Trailer [HD 1080P] | 3,565 | Preview |
| 83. | The NyanCave | 【 PSYCHONAUTS 2 】Sokugeki | Part 4 | Blind Gameplay Live Reaction | 3,435 | |
| 84. | Canadian Guy Eh | MIND BLOWING! - Psychonauts 2 LIVESTREAM | 3,378 | |
| 85. | Something Witty Gaming | Friday Night Stream! Psychonauts 2! Part 01 | 3,247 | |
| 86. | The NyanCave | 【 PSYCHONAUTS 2 】Fear and Loathing in Sense-Vegas | Part 5 | Blind Gameplay Live Reaction | 3,026 | |
| 87. | Open Surprise | Psychonauts 2 Gameplay on Xbox Series X 4K UHD 60FPS | 3,013 | |
| 88. | The NyanCave | 【 PSYCHONAUTS 2 】He know where things Gzar | Part 6 | Blind Gameplay Live Reaction | 2,982 | |
| 89. | Zoomg I زومجی | Psychonauts 2 Review 🔥 بررسی بازی سایکوناتز ۲ | 2,870 | Review |
| 90. | Kephren | Psychonauts 2 - How to BOOST FPS and Increase Performance on any PC | 2,858 | Guide |
| 91. | Proton Jon's Livestream Recordings | Game Clearing: Psychonauts 2 (Part 1) | 2,832 | |
| 92. | BossBattleChannel | Psychonauts 2 Boss 2 - Gluttonous Goats | 2,824 | |
| 93. | Plume Gaming | XBOX SERIES X|S - Flight Simulator EARLY PREVIEW on XBOX + Psychonauts 2 Is BIGGER Because of XBOX | 2,783 | Preview |
| 94. | BAI GAMING | Psychonauts 2 Pt7 Otto's Lab! Spare Brain! Psi King's Sensorium Walkthrough! | 2,764 | Walkthrough |
| 95. | The NyanCave | 【 PSYCHONAUTS 2 】GOTY (Grandma of the Year) | Part 7 | Blind Gameplay Live Reaction | 2,755 | |
| 96. | rdsca | Psychonauts 2 - Gameplay dans l'Académie des Psychonauts | 2,745 | |
| 97. | The NyanCave | 【 PSYCHONAUTS 2 】Nona? NO. NAH. | Part 8 | Blind Gameplay Live Reaction | 2,735 | |
| 98. | BAI GAMING | Psychonauts 2 Pt11 Strike City Walkthrough! Fixing Bowling Ford! | 2,541 | Walkthrough |
| 99. | GamersPrey | Psychonauts 2 - The Game Awards 2018 Trailer [HD 1080P] | 2,418 | Preview |
| 100. | Electric Playground Network - EPN | Psychonauts 2, Wakanda & Madden Reviews, Spidey News & NHL 22 - The Rundown - Electric Playground | 2,397 | Review |
