| 1. |  DeoxysPrime | Flying Battery Zone Act 1 - Sonic Mania [OST] | 1,649,966 | |
| 2. | DeoxysPrime | Doomsday Zone - Sonic & Knuckles [OST] | 651,752 | |
| 3. | TetraBitGaming | Sonic & Knuckles LOST BITS | Unused Content & Debug Features [TetraBitGaming] | 573,150 | |
| 4. | DeoxysPrime | Flying Battery Zone (Act 1) - Sonic & Knuckles [OST] | 551,229 | |
| 5. | DeoxysPrime | Act 1 Boss - Sonic & Knuckles [OST] | 477,616 | |
| 6. | DeoxysPrime | Mushroom Hill Zone (Act 1) - Sonic & Knuckles [OST] | 456,052 | |
| 7. | MD GameStation | All Knuckles Battles - Knuckles Series | 435,097 | |
| 8. | DeoxysPrime | Lava Reef Zone (Act 1) - Sonic & Knuckles [OST] | 432,613 | |
| 9. | DeoxysPrime | Flying Battery Zone (Act 2) - Sonic & Knuckles [OST] | 425,519 | |
| 10. | DeoxysPrime | Death Egg Zone (Act 1) - Sonic & Knuckles [OST] | 399,245 | |
| 11. | DeoxysPrime | Sky Sanctuary Zone - Sonic & Knuckles [OST] | 393,011 | |
| 12. | DeoxysPrime | Theme of Knuckles - Sonic & Knuckles [OST] | 384,555 | |
| 13. | DeoxysPrime | Sandopolis Zone (Act 1) - Sonic & Knuckles [OST] | 383,755 | |
| 14. | DeoxysPrime | Title Screen - Sonic & Knuckles [OST] | 359,372 | |
| 15. | DeoxysPrime | Credits - Sonic & Knuckles [OST] | 357,333 | |
| 16. | DeoxysPrime | Invincible - Sonic & Knuckles [OST] | 344,239 | |
| 17. | DeoxysPrime | Death Egg Zone (Act 2) - Sonic & Knuckles [OST] | 321,001 | |
| 18. | DeoxysPrime | Lava Reef Zone (Act 2) - Sonic & Knuckles [OST] | 307,194 | |
| 19. | BRICKfolk | Building MORE LEGO Sonic Tapes (Shin Sonic) | 302,294 | |
| 20. | DeoxysPrime | Sandopolis Zone (Act 2) - Sonic & Knuckles [OST] | 300,972 | |
| 21. | DeoxysPrime | Mushroom Hill Zone (Act 2) - Sonic & Knuckles [OST] | 297,646 | |
| 22. | DeoxysPrime | Ending - Sonic & Knuckles [OST] | 245,426 | |
| 23. | King Meteor Studios | Sonic & Knuckles - Death Egg [Bad Future Remix] | 102,659 | |
| 24. | King Meteor Studios | Sonic & Knuckles / Sonic 2 - Death Egg [Past Remix] | 99,086 | |
| 25. | Cartooning Club How to Draw | Sonic vs Knuckles Sketch Battle 🥊 sketchbook #shorts | 97,165 | Tutorial |
| 26. | King Meteor Studios | Sonic & Knuckles - Death Egg [Present Remix] | 66,957 | |
| 27. | King Meteor Studios | Sonic & Knuckles - Death Egg [Good Future Remix] | 64,571 | |
| 28. | MD GameStation | Knuckles Series VS Sonic Movie 1 Scene Comparisions | 62,677 | |
| 29. | Fortew3 | Sonic and Knuckles: Knuckles. Final Emerald Perfect score. | 50,934 | |
| 30. | Legendary Super Mario | (♪) Sonic 3 & Knuckles: Doomsday Zone (Touhou Remastered) | 49,251 | |
| 31. | FramePlay | Sonic 3 & Knuckles PC: 100% Playthrough + Knuckles Gameplay | 43,099 | Let's Play |
| 32. | King Meteor Studios | Sonic & Knuckles - Flying Battery [Bad Future Remix] | 38,146 | |
| 33. | King Meteor Studios | Sonic & Knuckles - Flying Battery [Good Future Remix] | 37,110 | |
| 34. | AlsoAlax | Preparing the Flying Battery! | 35,914 | |
| 35. | King Meteor Studios | Sonic & Knuckles - Flying Battery [Past Remix] | 31,381 | |
| 36. | Amazing Toys & Colors Review | Mixing”Sonic and Knuckles” Red & Blue Makeup,Eyeshadow,Glitter into Slime! Satisfying Slime Video | 30,397 | |
| 37. | The Review Spot | Collectible Spot - Meccano Sonic The Hedgehog Sonic and Knuckles Chemical Plant Racing Tracks | 29,490 | |
| 38. | King Meteor Studios | Sonic & Knuckles - Flying Battery [Present Remix] | 26,107 | |
| 39. | King Meteor Studios | Sonic & Knuckles - The Doomsday Zone (Cover) | 23,500 | |
| 40. | Jaypin88 | Sonic & Knuckles: Master Edition ~ All Special Stages & Bosses ✪ 60K Subscriber Special (1080/60fps) | 21,913 | |
| 41. | Jaypin88 | Sonic XG (Classic) ✪ Full Game (100%) Playthrough (1080p/60fps) | 17,572 | Let's Play |
| 42. | Mystic Falcon | Sonic 3 & Knuckles - Doomsday Zone with Lyrics | 17,293 | |
| 43. | King Meteor Studios | Sonic & Knuckles - Lava Reef [Bad Future Remix] | 16,014 | |
| 44. | Jaypin88 | Sonic & Knuckles: Master Edition (Demo) :: First Look Gameplay (720p/60fps) | 15,993 | |
| 45. | NonStopAntonio | Knuckles Episode 1 Easter Eggs / References | 15,694 | Show |
| 46. | Jaypin88 | Sonic & Knuckles: Master Edition (Demo 2) :: Second Look Gameplay (1080p/60fps) | 14,687 | |
| 47. | Jaypin88 | Sonic & Knuckles: Master Edition (SHC 2020 Demo) :: All Bosses (1080p/60fps) | 14,369 | |
| 48. | Legendary Super Mario | Sonic 3 and Knuckles: The Doomsday Zone (Super Sonic Battle) | 13,354 | |
| 49. | Jaypin88 | Sonic Mega Collection (GCN) | Pt.4: Sonic & Knuckles (1/2) | 12,275 | |
| 50. | Jaypin88 | Sonic & Knuckles 2 (Lost Demo) ✪ First Look Gameplay (1080p/60fps) | 12,162 | |
| 51. | Legendary Super Mario | (♪) Sonic 3 & Knuckles: Doomsday Zone V2 (Touhou Remastered) | 12,147 | |
| 52. | Jaypin88 | White Sonic in Sonic & Knuckles (SHC 16) :: Longplay (720p/60fps) | 11,360 | |
| 53. | Jaypin88 | S&K Collection (PC) | Sonic & Knuckles - All Emeralds (Knuckles) Speedrun in 28:58 | 11,288 | |
| 54. | Jaypin88 | Sonic 3 & Knuckles: Painto Edition || Walkthrough (720p/60fps) | 10,938 | Walkthrough |
| 55. | PrincessZelda2020 | Sonic and Knuckles - Doomsday Zone(Megaman 7 Remake) | 9,744 | |
| 56. | Sonic Terminal | A 3D Recreation of Sonic & Knuckles | 9,723 | |
| 57. | King Meteor Studios | Sonic & Knuckles - Give In To The Reef (Remix) | 9,696 | |
| 58. | NonStopAntonio | Shadow the hedgehog Teased in the Knuckles Series! | 9,176 | |
| 59. | Stellerby | Sonic & Knuckles with Lyrics - Flying Battery Zone | 9,095 | |
| 60. | CookMuk | Convenience Store RED BLUE Food mukbang with SHIN SONIC & KNUCKLES | SHIN SONIC TAPES | ASMR Mukbang | 8,812 | |
| 61. | Jaypin88 | Sonic Mega Collection (GCN) | Pt.4: Sonic & Knuckles (2/2) | 8,521 | |
| 62. | Jaypin88 | Sonic & Knuckles: Newtrogic Panic (Early Sage 2020 Demo) :: Walkthrough (1080p/60fps) | 8,407 | Walkthrough |
| 63. | King Meteor Studios | Sonic & Knuckles - Lava Reef: Act 2 / Hidden Palace (Cover) | 8,344 | |
| 64. | gabocarina96 | Flying Battery Zone - Sonic & Knuckles/Sonic Mania (Rock/Metal) Cover | Gabocarina96 | 7,743 | |
| 65. | Pikasprey Blue | Sonic and Knuckles: Double Panic | Fan Game | 6,545 | |
| 66. | 👑 Hooked on the Brothers 👑 | Get blue spheres! (Brothers playing Sonic and Knuckles) | 6,440 | |
| 67. | Jaypin88 | Sonic & Knuckles DX (SHC '24 - Lock-On Version) ✪ Sonic Shorts - Modified Roms | 6,056 | |
| 68. | Jaypin88 | Sonic 3D Blast (July 3, 1996 Prototype) :: Walkthrough (720p/60fps) | 5,984 | Walkthrough |
| 69. | King Meteor Studios | Sonic & Knuckles - Lava Reef Zone: Act 1 (Cover) | 5,945 | |
| 70. | The Beaverhouse | Sonic & Knuckles: Sandopolis Zone (Act 1) 8 Bit Remix | 5,849 | |
| 71. | CHIP FURNACE | Sonic & Knuckles - Flying Battery Zone Act 2 (Sonic Drinks Battery Acid) | 5,716 | |
| 72. | Jaypin88 | Sonic & Knuckles: Key Hunters DX (Sage 2020 Demo) :: Walkthrough (1080p/60fps) | 5,544 | Walkthrough |
| 73. | Napkins X ⭐ | ME AM!? (Sonic & Knuckles meme) | 5,517 | |
| 74. | Jaypin88 | Sonic XG (Classic) Finale ✪ Full Game (100%) Playthrough as Knuckles (1080p/60fps) | 5,036 | |
| 75. | Legendary Super Mario | Sonic Advance 3: Altar Emerald (Sonic and Knuckles) | 5,020 | |
| 76. | Newfie Bangaa | Let's Play Knuckles in Sonic 2 #01 - Chaos Overload | 5,002 | |
| 77. | Mathew Valente | Sonic & Knuckles: Flying Battery Zone 1 (SNES Version) | 4,703 | |
| 78. | Jaypin88 | Sonic Eclipse (Demo Version 2) :: Walkthrough (1080p/60fps) | 4,535 | Walkthrough |
| 79. | VirtualBoo | Sonic Origins-Sonic & Knuckles- Tails 100% Playthrough-All Chaos & Super Emeralds | 4,412 | Let's Play |
| 80. | Christopher Foss (Pyro Paper Planes) | Sonic & Knuckles - Lava Reef Zone [Redux] | 4,384 | |
| 81. | Damien | what happens if you put sonic and knuckles collection in a ps2? | 4,235 | |
| 82. | Jaymonius | EXTRA: Sonic and Knuckles random play | 3,962 | |
| 83. | Legendary Super Mario | (♪) Sonic 3 & Knuckles - Flying Battery Zone: Act 1 (Touhou Remastered) | 3,928 | |
| 84. | Stickman Guides | First Look At The Sonic Movie Spin-Off Knuckles Show! THE OVA HAT IS BACK! | 3,803 | Show |
| 85. | CHIP FURNACE | Sonic & Knuckles - Flying Battery Zone Act 2 (Dying Battery Zone) | 3,690 | |
| 86. | NonStopAntonio | Knuckles Episode 1 Review | 3,659 | Show |
| 87. | VirtualBoo | Sonic Origins-Sonic & Knuckles- Knuckles Playthrough | 3,416 | Let's Play |
| 88. | CookMuk | SHIN SONIC TAPES - Convenience Store Hot Vs Cold Food With Sonic & Knuckles Mukbang | ASMR Animation | 3,276 | |
| 89. | CHIP FURNACE | Sonic & Knuckles - Death Egg Zone Act 2 (Affronted) | 3,243 | |
| 90. | CookMuk | Convenience Store RED BLUE Food mukbang with SHIN SONIC & KNUCKLES | SHIN SONIC TAPES | ASMR Mukbang | 3,188 | |
| 91. | Jaypin88 | Sonic & Knuckles: Newtrogic Panic (Sage 2019 Demo) :: First Look Gameplay (720p/60fps) | 3,129 | |
| 92. | CHIP FURNACE | Sonic & Knuckles Flying Battery Act 2 (Descending the brown note to Hell Version) | 3,047 | |
| 93. | NonStopAntonio | Knuckles Episode 4 Review | 3,028 | Show |
| 94. | SuperGirlKels | Sonic the Hedgehog 3 & Knuckles (Genesis) Part 2/2 (Sonic & Knuckles) in 1 Hour | 3,006 | |
| 95. | CHIP FURNACE | Sonic the Hedgehog 3 & Knuckles - The Doomsday Zone (Welcome to Hell) | 2,982 | |
| 96. | Jaypin88 | Sonic & Knuckles: Jk.fox Edition :: Walkthrough (720p/60fps) | 2,928 | Walkthrough |
| 97. | CHIP FURNACE | Sonic & Knuckles Flying Battery Act 1 (Wobble Battery) | 2,891 | |
| 98. | CHIP FURNACE | Sonic & Knuckles - Sky Santuary Zone (Battered Trumpet Version) | 2,885 | |
| 99. | Jaypin88 | Key Hunters DX (Sample Demo) ✪ First Look Gameplay (1080p/60fps) | 2,823 | |
| 100. | King Meteor Studios | Sonic & Knuckles - Sky Sanctuary Zone (Cover) | 2,822 | |
