| 2025-06-12 |  MelodyVictoria | VOD: Mel finally let us jump down this funny trap door again! || The Binding of Isaac | 0:00 | 4 |
| 2025-06-12 | voidcatling | why is this basement so big? the binding of isaac | 0:00 | 16 |
| 2025-06-12 | Cirno_TV | Cirno Plays Binding of Isaac 2025 - #1 | 0:00 | 36 |
| 2025-06-10 | The Cup Holderr | Lilth greedier run - Binding of Isaac | 0:00 | 1 |
| 2025-06-02 | Fiendzy | Zandro - SH → Isaac co-op | 6:54:09 | 9 |
| 2025-06-02 | The Cup Holderr | FIRST VTUBE STREAM - Binding of Isaac | 0:00 | 1 |
| 2025-05-27 | Ericsson Live | JACOB V2 vs The LAMB - The Binding of Isaac | 0:00 | 3 |
| 2025-05-26 | The Cup Holderr | Finishing story unlocks the last runs - Binding of Isaac | 0:00 | 2 |
| 2025-05-26 | OpenVentureJon | BINDING OF ISAAC WITH THE BOISS | 0:00 | 8 |
| 2025-05-22 | The Cup Holderr | Finishing story unlocks - Binding of Isaac | 0:00 | 8 |
| 2025-05-22 | Ericsson Live | JACOB et ESAU vs GREEDIER : 😭 ENFIN La FIN Des V1 - The Binding of Isaac | 0:00 | 3 |
| 2025-05-22 | Roger Cheeto | isaac || THE ROAD AHEAD || Homunculus Oniisan Vtuber | 0:00 | 1 |
| 2025-05-20 | The Cup Holderr | Unlocking the forgotten - Binding of isaac | 0:00 | 1 |
| 2025-05-20 | YoungkCha | Isaac Bootcamp Starts Now - Tainted Lost vs Delirium [1] | 0:00 | 52 |
| 2025-05-18 | Ericsson Live | BETHANY vs GREEDIER : MEME PAS PEUR ! - The Binding of Isaac | 0:00 | 0 |
| 2025-05-18 | QSquid33 | UM??? Bombs??? #bindingofisaac #shorts | #qsquid33 on #Twitch | 0:00 | 1,472 |
| 2025-05-17 | QSquid33 | Never Takes Damage Ever #bindingofisaac #shorts | #qsquid33 on #Twitch | 0:00 | 1,248 |
| 2025-05-16 | Ericsson Live | FORGOTTEN PREND ENFIN SA REVANCHE SUR GREDDIER - The Binding of Isaac | 0:00 | 6 |
| 2025-05-15 | The Cup Holderr | Isaac-chan! @lazymattman #bindingofisaac #meme #rubychan #isaac #funny #loud #gaming #shorts | 0:00 | 3,698 |
| 2025-05-14 | Ericsson Live | TAINTED ISAAC EPLOSE MEGA SATANT ! - The Binding of Isaac | 0:00 | 6 |
| 2025-05-14 | The Cup Holderr | time to game break binding of isaac | 0:00 | 1 |
| 2025-05-13 | Ericsson Live | LOST + R KEY ATOMISE MEGA SATAN - The Binding of Isaac | 0:00 | 5 |
| 2025-05-11 | QSquid33 | Supersonic Baby! #bindingofisaac #shorts | #qsquid33 on #Twitch | 0:00 | 467 |
| 2025-05-11 | Asprey Archive | Binding of Isaac: Reverie (Touhou Mod) | Part 17 | 0:00 | 1,189 |
| 2025-05-10 | Ericsson Live | KEEPER FAIT ENFIN SON GREEDIER - The Binding of Isaac | 0:00 | 14 |
| 2025-05-06 | QSquid33 | Squid Has Beef With UPS... And Her Friend Apparently #bindingofisaac #shorts | #qsquid33 on #Twitch | 0:00 | 1,214 |
| 2025-05-05 | QSquid33 | Bottom? Yes I Am. Innocent? No You Aren't #bindingofisaac #shorts | #qsquid33 on #Twitch | 0:00 | 968 |
| 2025-05-04 | QSquid33 | She Had Instant Regrets #bindingofisaac #shorts | #qsquid33 on #Twitch | 0:00 | 677 |
| 2025-05-02 | Lucasu | 🔴LIVE: [Chat n Chill] - I Heard This Game Was Good, Let's See If It's True... | 0:00 | 148 |
| 2025-04-30 | QSquid33 | Sometimes It's Best To Just Not Say Anything... #bindingofisaac #shorts | #qsquid33 on #Twitch | 0:00 | 115 |
| 2025-04-28 | QSquid33 | Isaac And His Isaac Lived Alone In A Small Isaac On A Isaac... | 0:00 | 6 |
| 2025-04-26 | Ericsson Live | TAINTED JUDAS vs HUSH - The Binding of Isaac | 0:00 | 16 |
| 2025-04-22 | QSquid33 | Death Noise #bindingofisaac #shorts | #qsquid33 on #Twitch | 0:00 | 345 |
| 2025-04-22 | OogieGabi | Isaac THE MOVIE!!! | 0:00 | 2 |
| 2025-04-19 | Fiendzy | Starting a new isaac save | 0:00 | 15 |
| 2025-04-16 | Sroxah | Accidental Composting Expert | The Binding of Isaac | 0:00 | 15 |
| 2025-04-09 | Lucas Pereira | The Binding of Isaac OST - Satan's theme vs Teminite - Final Boss (Will Make It Party Time) Mashup | 0:00 | 13 |
| 2025-04-08 | QSquid33 | The Binding Of Isaac; Repentance (Part 32) | 0:00 | 7 |
| 2025-04-04 | Sroxah | Playing Binding of Isaac With FIRE MIND Makes Everything EXPLODE! | 0:00 | 83 |
| 2025-03-18 | MatchaSoup | playing isaac modded | 0:00 | 16 |
| 2025-03-17 | rinimt | Binding of Bullets | Schism [Gameplay] | 0:00 | 53 |
| 2025-03-10 | Hixel Bay | 💀 Binding of Isaac 💀 | Triple Dead God #8 | 0:00 | 40 |
| 2025-03-08 | Sroxah | I Didn’t Mean to Walk in Here! – The Binding of Isaac Repentence+ | 0:00 | 31 |
| 2025-03-08 | Hixel Bay | 💀 Binding of Isaac 💀 | Triple Dead God #7 | 0:00 | 24 |
| 2025-03-06 | Hixel Bay | 💀 Binding of Isaac 💀 | Triple Dead God #6 | 0:00 | 8 |
| 2025-03-05 | Hixel Bay | 💀 Binding of Isaac 💀 | Triple Dead God #5 | 0:00 | 28 |
| 2025-03-04 | OogieGabi | He done goofed Up #bindingofisaac | 0:00 | 8 |
| 2025-03-02 | OogieGabi | Ouga Bouga Isaac #bindingofisaac | 0:00 | 88 |
| 2025-02-06 | Sroxah | My First Binding of Isaac Game in 10 YEARS - What Changed? | 0:00 | 95 |
| 2025-01-10 | Tom Vs Everything | Finally Played This Legendary Roguelike | The Binding of Isaac | 0:00 | 351 |
| 2024-12-28 | The Cup Holderr | Tainted lost pained me too much, i'm playing siege | 0:00 | 5 |
| 2024-12-26 | Hot Dog Streamé | 🎮 RELAXO ISAACO ?? 🎮- 👕 !ANRO 👕 #Qc #goingrogue #roguesociety | 0:00 | 12 |
| 2024-12-23 | Ericsson Live | Isaac - Hush prend très cher contre Forgotten 😮😮😮 | 0:00 | 6 |
| 2024-12-10 | CodeChannel | 🏎️Rally 2011 LED Storm (Caplossal Credit Feed Run) Ep.1 -- The Car Boxing Gas Shortage of 2011 | 0:00 | 8 |
| 2024-12-08 | waterspritE | Download it now! #gameplay #games #gaming #game #mobilegame #androidgame #addictinggames | 0:00 | 393 |
| 2024-12-07 | Hixel Bay | #yeet random items in #RealityCore 🔫 | 0:00 | 428 |
| 2024-12-05 | Ruzllx | The Breaking Of Isaac | 0:00 | 8 |
| 2024-12-01 | RomeLIVE | Beating The HARDEST Challenge in The Binding of Isaac | 0:00 | 303 |
| 2024-11-29 | SuperbHappyGuy | Cathedral unlocks this EARLY?? | 0:00 | 3 |
| 2024-11-26 | RomeLIVE | A New TEAR EFFECT Just Dropped... It's INSANE: | 0:00 | 2,915 |
| 2024-11-24 | RomeLIVE | They Added a New WEAPON to Isaac... It's AMAZING: | 0:00 | 1,077 |
| 2024-11-22 | GetTwoBirdsStonedAtOnce | The Binding of Isaac, whatever is the newest DLC, that's it | 0:00 | 3 |
| 2024-11-21 | RomeLIVE | I Found The BEST T Keeper Rig: | 0:00 | 2,172 |
| 2024-11-20 | RomeLIVE | They BUFFED Old Items... They're INSANE Now: | 0:00 | 2,110 |
| 2024-11-16 | RomeLIVE | Finally, Cricket's Head TWO: | 0:00 | 3,137 |
| 2024-11-15 | GamersPrey | The Binding of Isaac Multiplayer Online Gameplay Reveal #shorts #bindingofisaac #gameplay | 0:00 | 1,348 |
| 2024-11-11 | Coin | Coincast: The Binding of Isaac | 0:00 | 28 |
| 2024-11-10 | RomeLIVE | They Finally Added QUALITY 5 Items: | 0:00 | 3,285 |
| 2024-11-10 | PatellaVT(Vods) | The Binding of Isaac Part 3 | 0:00 | 8 |
| 2024-11-09 | RomeLIVE | We Got a NEW Mutant Spider... It's SPECTACULAR: | 0:00 | 3,682 |
| 2024-11-07 | RomeLIVE | Sacred Heart Just Got a DEVIOUS Upgrade: | 0:00 | 2,947 |
| 2024-11-05 | PatellaVT(Vods) | The Binding of Isaac Part 2 | 0:00 | 11 |
| 2024-10-27 | RomeLIVE | PHD 2 Just Dropped... It's TWISTED: | 0:00 | 3,160 |
| 2024-10-26 | RomeLIVE | How Diplopia 2.0 Gave Me 450 THOUSAND DAMAGE | 0:00 | 4,065 |
| 2024-10-26 | RomeLIVE | This NEW Item Makes Tainted Lost a Joke: | 0:00 | 2,010 |
| 2024-10-25 | RomeLIVE | Cricket's Head 2 Dropped... It's INCREDIBLE: | 0:00 | 3,394 |
| 2024-10-24 | RomeLIVE | They Made a RED Map... It Spawns INFINITE Red Rooms: | 0:00 | 3,155 |
| 2024-10-23 | RomeLIVE | Finally, GIGA BRIM In Isaac: | 0:00 | 4,273 |
| 2024-10-22 | Patthiccness | Patthiccness Best Of 2020 - 2024 | 0:00 | 127 |
| 2024-10-21 | PatellaVT(Vods) | The Binding of Isaac Part 1 | 0:00 | 11 |
| 2024-10-21 | RomeLIVE | Cricket's Body Got UPGRADED... It's PREPOSTEROUS: | 0:00 | 2,892 |
| 2024-10-20 | RomeLIVE | Honey wake up, INFESTATION 3 dropped and it's AMAZING: | 0:00 | 2,166 |
| 2024-10-18 | RomeLIVE | They Made GUPPY 2... It's INCREDIBLE: | 0:00 | 2,584 |
| 2024-10-17 | RomeLIVE | We Made Spindown Dice 2... It's WILD: | 0:00 | 3,489 |
| 2024-10-16 | Ericsson Live | Isaac - Apollyon conter Hush ET Delirium 😮😮😮 | 0:00 | 7 |
| 2024-10-16 | RomeLIVE | I Have NEVER Broken Isaac THIS Fast... | 0:00 | 2,137 |
| 2024-10-15 | RomeLIVE | THIS is Tainted Keeper's DREAM Item: | 0:00 | 3,073 |
| 2024-10-14 | Ericsson Live | Isaac - Apollyon en Boss Rush ☠️☠️☠️ | 0:00 | 3 |
| 2024-10-14 | RomeLIVE | Death's List 2 Just Dropped... It's INSANE: | 0:00 | 2,284 |
| 2024-10-13 | RomeLIVE | This Mod Changes BAD Items Into INSANE Stats: | 0:00 | 2,601 |
| 2024-10-06 | RomeLIVE | We Made a NEW Syringe Item... It's INSANE!! | 0:00 | 3,028 |
| 2024-10-06 | RomeLIVE | How This NEW Guppy Item DEMOLISHED My Run... | 0:00 | 1,892 |
| 2024-10-05 | RomeLIVE | Duality 2 Just Dropped... It's CRAZY!!: | 0:00 | 2,344 |
| 2024-10-04 | RomeLIVE | How ONE Item Gave me INFINITE Tear Rate: | 0:00 | 2,586 |
| 2024-10-03 | RomeLIVE | We Made Small Rock 2... It's AMAZING!!: | 0:00 | 3,318 |
| 2024-10-01 | RomeLIVE | We Upgraded the D6... It's SENSATIONAL: | 0:00 | 2,856 |
| 2024-09-30 | RomeLIVE | They Released Isaac 2... He's ADORABLE: | 0:00 | 2,141 |
| 2024-09-28 | Ericsson Live | Isaac - Cain versus Greedier 🙊🙉🙈☠️☠️☠️ | 0:00 | 14 |
| 2024-09-28 | RomeLIVE | How I Turned Isaac Into a WIZARD: | 0:00 | 3,482 |
| 2024-09-27 | RomeLIVE | This Item Gives You The CRAZIEST Stats: | 0:00 | 2,168 |
