| 2 days ago |  KrisVT | 46 | Isaac runs and later Conquest of Azeroth:Alpha | 0:00 |
| 2025-07-30 | Momonga Altosk | 1,380 | Some the Binding of Isaac and Reverse 1999 | 0:00 |
| 2025-07-28 | ProblemsIRL | 4,360 | Spending or Saving | 0:00 |
| 2025-07-21 | Shiny | 346 | Shiny Spielt paar Roguelikes | The Binding of Isaac, Pokerogue | 0:00 |
| 2025-07-17 | Poltergeist | 6,430 | AZAZEL LUCK IS UNMATCHED #gaming #thebindingofisaac | 0:00 |
| 2025-07-16 | Giuso | 63 | Das erste mal ☠️ | The Binding of Isaac | Part 1 | 0:00 |
| 2025-07-09 | Hopplhase | 770 | Blind auf beiden Ohren! - I.RULE | 0:00 |
| 2025-07-07 | Mycromator | 214 | Don't ask why but I'm playing flash Isaac in 2025 (livestream) | 0:00 |
| 2025-06-13 | OdinakaJesus | 162,000 | Mehr BINDING OF ISAAC mit @Zombey ! | 0:00 |
| 2025-06-11 | TheRealAntoxx | 1,150 | ADDIO MONSTRO!!! THE BINDING OF ISAAC BLIND RUN ITA #isaac #thebindingofisaacafterbirthplus | 0:00 |
| 2025-05-30 | FloncLive VODs | 37 | Zurück auf Anfang! | The Binding of Isaac | Hau das Urgl! Bestrafung #2 | 0:00 |
| 2025-05-18 | Bambochutafreak | 7,750 | The Worst Trinkets in The Binding of Isaac! | 0:00 |
| 2025-05-03 | Sir Try-alot | 79 | Isaac Stream | 0:00 |
| 2025-04-30 | PliXaZ | 356 | TBOI | Neuer Spielstand - Nun auch Aktiver mit Isaac | The Binding of Isaac | @PliXaZ | 0:00 |
| 2025-04-17 | The AndroidFerret | 6,540 | I think it's a demo? i cannot progress | 0:00 |
| 2025-03-12 | Eddi | 128 | Star of Providence | The Binding of Isaac, nur anders? | 0:00 |
| 2025-02-25 | SteinImVorgarten | 30 | Isaac hasst mich irgendwie glaube ich... | 0:00 |
| 2025-02-18 | Sirloin | 1,470,000 | What if you play Isaac (The Binding of Isaac) in Mario Kart 8 (Mushroom Cup) (HD) | 0:00 |
| 2025-02-06 | GameStar Talk | 53,700 | 1.000 Stunden gespielt: Warum tue ich mir das an? | The Binding of Isaac | 0:00 |
| 2025-01-26 | Masokuu | 947 | [Coop] Binding Isaac with @masamoonmoon - Deez lags | 0:00 |
| 2024-12-27 | Chelor Belor | 12 | [VOD] me at my sisters wedding vs me when isaac online coop | 0:00 |
| 2024-12-23 | Aranox | 1,390 | Bisschen Isaac zu Weihnachten | 0:00 |
| 2024-12-15 | FeineKatze | 74,500 | Unter Swapper-Katze leidet die ganze Lobby! | 0:00 |
| 2024-11-22 | TheRealBanjo | 279 | The Binding of Isaac MULTIPLAYER?! | 0:00 |
| 2024-11-20 | HandOfUncut | 1,360,000 | Neuer Multiplayer Modus in The Binding of Isaac | 0:00 |
| 2024-11-14 | LetsPlayKeldeo | 426 | 3DS Capturecard Test Stream The binding of Isaac 2017 | 0:00 |
| 2024-10-24 | Rdy2Game | 6,260 | Pocket Necromancer gameplay action survival rpg android game part2 | 0:00 |
| 2024-10-17 | Junoosch | 1,230 | Wenn ich sterbe ➡️NEUES ROUGELIKE (Challenge)! | 0:00 |
| 2024-09-30 | LeKris | 217 | Herzcontainer werden völlig überbewertet ❤️ - The Legend of Zelda - Dungeons of Infinity [PC] | 0:00 |
| 2024-09-24 | Agent Scaller | 89 | The Binding of Isaac: Maggie Run | 0:00 |
| 2024-09-22 | Killerkeks TV | 42 | Was ist das für eine verrückte Ebene! Teil: 2 /The Binding of Isaac | 0:00 |
| 2024-09-20 | Legends Katze | 70 | Binding of isaac | 0:00 |
| 2024-09-19 | Killerbunny | 834 | The Binding of Isaac | Wir müssen das Herz Zerstören?! Part(2) | 0:00 |
| 2024-08-26 | Until Downfall | 18 | The binding of Isaac #2 | OP Run mit Angeldeal | 0:00 |
| 2024-07-31 | Marmus | 634 | Малекий забег за большого персонажа Bael Gameplay #Bael #isaac #repentance #gameplay | 56:46 |
| 2024-07-26 | Wolverous | 97,800 | The Binding Of Isaac Forever #172 - Eine traurige Nachricht | 0:00 |
| 2024-07-18 | BlackHand | 30,100 | Isaaac! | 1:40:24 |
| 2024-06-23 | Wintar Streams | 115 | KILL KNIGHT [Demo] | sirWintar | 46:54 |
| 2024-06-04 | Surny: VOD Archive | 687 | June 3, 2024 - Isaac | 1:03:23 |
| 2024-05-22 | 13lackJ8ck | 258 | Ab in den Keller!☹️Schwerste Schwierigkeit: Schwer😎!daily[143/366] | 4:28:07 |
| 2024-05-21 | Bardocksen | 95 | Binding of Isaac - The Forgotten freischalten - !liebe !party !gubbel FSK18+ | 4:37:11 |
| 2024-05-20 | SPACE GAMING | 313,000 | Warum gerade alles Rogue Like ist | 9:52 |
| 2024-05-13 | El_Powel | 112 | Magic Mushroom got us like O: | el_powel auf #Twitch | 0:13 |
| 2024-04-09 | Rickos Random Funtime | 91 | When Life gives you Lemons | The binding of Isaac [GER VTuber] | 26:06 |
| 2024-04-06 | GameJam Deutschland | 356 | The Host Challenge Hassenswerte Dinge passieren in The Binding of Isaac GameJam Deutschland | 33:48 |
| 2024-03-03 | Dopppelmoppel23 | 21 | Ultra Hard Attempts Marathon🥲🥲🥲 | 1:44:37 |
| 2024-02-12 | OffL1N3 | 20 | The Binding Of Isaac und Talk | 28:55 |
| 2024-01-28 | Mischko | 76 | Let's Play The Binding of Isaac #028 [Deutsch] Endboss again | 1:07:47 |
| 2024-01-21 | Roach | 271 | Tarnished Maggy freischalten ist eine Qual - Issac Repentance Epiphany Mod | 40:41 |
| 2024-01-20 | Blutsense | 52 | [2024/01/10] This title... also exists | 3:21:20 |
| 2024-01-14 | BadHairlineProductions | 13,400 | The Binding Of Isaac /// Divine Combat [Groovy Guitar] | 2:21 |
| 2024-01-09 | Hikaru | 331 | The Binding of Isaac | 1:39:45 |
| 2023-12-21 | Puschl | 275 | Attractbrim #gameplay #gaming #letsplay #isaac #deutsch #pc #pcgaming #tboi | 0:09 |
| 2023-12-19 | Noctuh | 25 | Der Run war schrecklich, aber hey, ich hab Azazel | The Binding Of Isaac # 3 | 52:01 |
| 2023-12-08 | PietSmiet Live | 165,000 | Binding of Isaac trifft Noita | Magicraft | 4:34:39 |
| 2023-12-06 | Burgerbox | 335 | I played the binding of isaac [9] | 11:37 |
| 2023-12-01 | gutelaunetyp | 49,800 | Timzember Tür 2 - B wie The Binding of Isaac #sammeln #sammlung | 0:51 |
| 2023-12-01 | OberkommissarT | 27,500 | NEUER BANGER GEHEIMTIPP! Binding Of Isaac + Noita Gestörte Zauberkombos! Böllern extrem! | Magicraft | 55:18 |
| 2023-11-24 | Beste Feinde | 15 | Binding of Isaac - Beste Runde so far 2 | 29:34 |
| 2023-11-06 | SilentGhost | 4,570 | DARKGEMS | 100% Platinum Walkthrough | Trophäen & Achievement Guide | 24:21 |
| 2023-10-21 | Slash | 360 | Pride Day - The Binding of Isaac REPENTACE - #137 [GER] | 52:11 |
| 2023-10-08 | WuTanfall LP | 998 | Gegner weg weinen #1 | Let's Play [German] | 28:25 |
| 2023-06-30 | Mr. su1ts | 30 | Wir zocken Brotato - Kein Mikro | 1:29:42 |
| 2023-06-18 | Asta | 5 | The Binding of Isaac: Ein mal und nie wieder | 12:07 |
| 2023-06-10 | Luis Gaming Test | 12,700 | SD8Gen1 - Exagear Hugo: Binding of Isaac/ Turnip/ Wine 8.2 staging/ Poco F4 GT | 8:05 |
| 2023-06-05 | NixMulti | 74 | 🟢Crowd Control Activ , ist das eine gute Idee ?! | #CrowdControlActiv🟢 | ♥!insta !kofi !Soun | 3:53:31 |
| 2023-06-02 | Luz Delight | 7,550 | Grow Your Guarden #01 | 11:08 |
| 2023-05-31 | schlonko | 1 | Technische Probleme the Binding of Isaac (9) 💀🤖 | 15:39 |
| 2023-05-29 | ThMurphy | 7 | #31 The Binding of Isaac | 50:07 |
| 2023-05-19 | The Binding of Isaac Lore | 8 | The Binding of Isaac: Das Geheimnis um Magdalene | 2:57 |
| 2023-05-15 | Brettspielblog - Die besten Brettspiele im Test | 32,000 | Ist The Binding Of Isaac: Four Souls das richtige Spiel für dich? | 21:37 |
| 2023-05-15 | RaLLe | 518 | Cavity Busters ★ GamePlay ⭐ Achievement Hunt 💛 XSX ⭐ | 1:09:20 |
| 2023-05-01 | MikeBisasam | 639 | (Ger) Isaac Four Souls Ultimate Collector's Box KS Edition Unboxing! | 36:33 |
| 2023-04-23 | Locke - let's play | 3 | The Binding of Isaac - Herausforderung #5-Zähigkeit | 43:30 |
| 2023-03-25 | KashXans | 45 | LET'S TEST THE BINDING OF ISAAC #001 | 7:58 |
| 2023-03-25 | 3x3cut10n | 57 | the binding of isaac pt3 es lief gut bis es nicht mehr gut lief | 1:24:46 |
| 2023-03-08 | Willi Wolff | 1 | The Binding of Isaac: (2011) Wrath of the Lamb | 7:02 |
| 2023-01-24 | Loremeister | 2,810 | ISAAC STREAM TEST #00 - vor Mom erstmal Victory Lab - - Let's Play The Binding of Isaac: Repantance | 1:04:18 |
| 2022-12-30 | Red Rage Crew | 5,050 | Binding of Isaac - Maddin Lost Episode 🎅🏼 | 0:00 |
| 2022-12-15 | Der Ninjastreamer | 64 | Wir wollten The Binding of Isaac und dann wurde es Pokemon O_o | 1:49:53 |
| 2022-12-10 | NatiesWelt | 0 | The Binding of Isaac the beginning | 25:51 |
| 2022-12-08 | Rebecca Doodles | 81,900 | Playing Binding of Isaac with MORE enemies | 2:28:54 |
| 2022-12-04 | BaBa Silberwolf | 175 | The Binding of Isaac | 1:08:46 |
| 2022-11-28 | ArcaneSentinel | 122 | Binding of Isaac Repentence Action | 41:18 |
| 2022-11-12 | PeterLP | 8 | BROTATO Ersteindruck | 38:37 |
| 2022-11-11 | Vortoxium | 446 | The Binding of Isaac - Main Theme [SM64 Soundfont] | 1:59 |
| 2022-10-13 | RandomSnake | 4,220 | Nach 2 Jahren Hush ENDLICH besiegt! - The Binding of Isaac #shorts | 0:30 |
| 2022-10-06 | Steam Deck Checker | 13,900 | Check my Steam Deck Library - The Binding of Isaac | 8:11 |
| 2022-10-03 | Taiga | 98 | The Binding of Isaac Daily Run | 19:02 |
| 2022-09-30 | Fakex | 8 | backwards challenge / The Binding Of Isaac | 1:50 |
| 2022-09-24 | HISKI Stream | 70 | The Binding of Isaac - Stream vom 21.09.2022 | 2:34:39 |
| 2022-09-17 | 2club | 30 | The Binding of Isaac - Ohh Yeah! #shorts | 0:15 |
| 2022-09-08 | sneemuni | 489 | Tutorial: How to become Me in The Binding of Isaac | 1:00 |
| 2022-08-28 | _ObRaZeC_ | 41 | Стрим - The Binding of Isaac | 25:40 |
| 2022-08-22 | Kritten | 464 | i dunno, Beast run with Fiend | 1:13:38 |
| 2022-08-20 | DOGumente - Das TEAM DOGS Archiv | 181 | Wer braucht Lammkulte? Wir haben Isaac! | THE BINDING OF ISAAC | 42:15 |
| 2022-08-19 | Fuyumi Toba - Twitch VODs | 1,290 | Summer Subathon #20 The Binding of Isaac | 2:08:33 |
| 2022-07-27 | wildfremd | 2,050 | Reynard angespielt: Action-Roguelike (Deutsch Gameplay) | 17:39 |
| 2022-07-20 | Zombie Cat | 163 | Backpack Hero #16 | 31:09 |
| 2022-07-16 | 1up Indie | 12,300 | Binding of Isaac/rogue like map #2 [Game Maker Studio 2 | Epic] | 24:58 |
