| 1. |  SSundee | MEET My NEW FAMILY (Game Of Life 2) | 9,363,901 | |
| 2. | ItsFunneh | She's a POPSTAR in Game of Life 2! | 7,255,416 | |
| 3. | Aphmau | A BOY OR A GIRL!? | Game Of Life PT.2 | 3,748,464 | |
| 4. | VanossGaming | The Game of Life 2 - My $200,000 Amazon Bill and Wildcat's Terrible Life! | 3,156,936 | |
| 5. | SSundee | I MET MY NEW CHILD! (Game Of Life) | 2,316,696 | |
| 6. | VanossGaming | The Game of Life 2 - "Asian Privilege" For The Win! | 2,167,733 | |
| 7. | VanossGaming | The Game of Life 2 - Playing a Racist Board Game | 1,787,834 | |
| 8. | Aphmau | Catching My Husband! | Game Of Life PT.1 | 1,384,089 | |
| 9. | ItsFunneh | Becoming The Richest Princess in Game Of Life 2! | 1,331,888 | |
| 10. | VanossGaming | Game of Life 2 - Dedicating My Life to Laptop Upgrades!! | 1,240,676 | |
| 11. | InquisitorMaster | The Squad Plays The Game Of Life! | 1,147,754 | |
| 12. | VanossGaming | The Game of Life 2 - Making Fake LinkedIn Profiles! (Funny Moments) | 1,017,149 | |
| 13. | K-City Gaming | Ava Gets Married in THE GAME OF LIFE 2! K-City | 969,591 | |
| 14. | EazySpeezy | I speedrun (the game of) life | 842,011 | |
| 15. | ChilledChaos | The CIRCLE OF LIFE! | Marriage or Bankruptcy? (The Game Of Life Online) | 839,206 | |
| 16. | Aphmau | How To Get The BEST LIFE! - [GAME OF LIFE #1] | 791,047 | |
| 17. | GameGrumps | Eggs? Scrambled? | The Game of Life 2 [ROUND 2-1] | 639,206 | |
| 18. | CaRtOoNz | GET RICH OR DIE TRYIN'!!! 💰☠️ | The Game of Life | 605,833 | |
| 19. | Aphmau | The One With The MOST Kids WINS! - [GAME OF LIFE #2] | 538,696 | |
| 20. | GameGrumps | There are many benefits to being a marine biologist | The Game of Life 2 [ROUND 2-2] | 525,628 | |
| 21. | Secret Sleepover Society | The @Drawfee Hosts are Competing to See Who Lives Best in THE GAME OF LIFE 2 | 478,339 | |
| 22. | GameGrumps | Skweezy Jibbs teaches us about life | The Game of Life | 457,463 | |
| 23. | GameGrumps | Arin will never go to college | The Game of Life 2 | 398,224 | |
| 24. | CaRtOoNz | ONE GAME TO RULE THEM ALL... | The Game of Life | 388,349 | |
| 25. | ElasticDroid | Youtubers Fight Over The Best Life | 311,349 | |
| 26. | WILDCAT | The Game of Life 2 but I become the most educated caveman ever… | 310,624 | |
| 27. | JeromeACE | How Many Is TOO Many In The Game Of Life 2 | JeromeACE | 289,590 | |
| 28. | JeromeACE | I Am The SMARTEST Player In The Game Of Life 2 | JeromeACE | 266,515 | |
| 29. | Secret Sleepover Society | Julia and Jacob are Finally Alive in THE GAME OF LIFE 2 | 251,935 | |
| 30. | WILDCAT | The Game of Life 2 But I'm a Single Lonely Billionaire | 232,228 | |
| 31. | jenn | who is the best at LIFE? | 209,714 | |
| 32. | Stumpt | Game of Life 2 - Rebooting The Board Game! (4-Player Gameplay) | 202,290 | |
| 33. | CaRtOoNz | DELIRIOUS HAS NEVER HAD A LIFE... | Game of Life 2 | 199,751 | |
| 34. | Ohmwrecker / Maskedgamer | The Game of Life 2... but we all have the same WIFE!? | 198,834 | |
| 35. | JeromeACE | Becoming A Dragon Tamer In The Game Of Life 2 | 185,418 | |
| 36. | WILDCAT | The Game of Life 2 made my friends groomers… | 183,818 | |
| 37. | JeromeACE | Becoming A Youtuber In The Game Of Life 2 | 170,842 | |
| 38. | Nintendo of America | The Game of Life 2 - Launch Trailer - Nintendo Switch | 168,656 | Preview |
| 39. | ChilledChaosGAME | A TRIPLE THREAT MATCH! (Game Of Life 2 | No Time To Relax | Mario Party SuperStars) | 163,130 | |
| 40. | Mr. Fruit | When the game is WAY too realistic | 162,575 | |
| 41. | ChilledChaosGAME | LIVING MY BEST LIFE! | The Double Feature Returns! (Game Of Life 2 & No Time To Relax) | 159,141 | |
| 42. | LetsPlay | Is the Key to Life College Loans? - The Game of Life 2 w/ Kayla | 158,637 | Let's Play |
| 43. | Ohmwrecker / Maskedgamer | The Game of Life 2... but the WHEEL was MERCILESS! (and I stole Rob's wife again) | 157,729 | |
| 44. | Verzichten | [ALL POV] EVERYONE Thought Sykkuno is "CHEATING" in THE GAME OF LIFE 2 Because of his LUCKY ROLLS! | 148,279 | |
| 45. | JeromeACE | Becoming A MAGE In The Game Of Life 2 | 146,905 | |
| 46. | Bay Area Buggs | I'm A Real Estate Mogul in The Game of Life 2! | 145,016 | |
| 47. | The Losers | Who Can Live The WORST Life In Game Of Life 2 | 137,569 | |
| 48. | ChilledChaosGAME | THE GAME OF LIFE...HAS A SEQUEL?! (The Game of Life 2 w/ Friends) | 137,236 | |
| 49. | Ohmwrecker / Maskedgamer | The Game of Life 2... but my PUPPY was the real PRIZE! | 137,030 | |
| 50. | LankyBox | LANKYBOX Got MARRIED In GAME OF LIFE 2!? (FUNNY MOMENTS!) | 135,048 | |
| 51. | Disguised Toast - Behind The Scenes | "Game of Life with Amigops" Full Stream | Disguised Toast - Valkyrae - Sykkuno, etc... | 132,978 | |
| 52. | JeromeACE | Becoming A Dino Tamer In The Game Of Life 2 | 130,658 | |
| 53. | Annoying Orange Gaming | Grapefruit FAILS - GAME OF LIFE #2 | 126,656 | |
| 54. | JeromeACE | Becoming A MILLIONAIRE in The Game of Life 2 w/ SSundee | 126,294 | |
| 55. | iHasCupquake | My Husband Had A Baby WITHOUT ME?! - Game Of Life 2 | 124,606 | |
| 56. | jenn | i flopped at life | 119,923 | |
| 57. | Sigils | I'm Getting a Girlfriend! (Game of Life 2) | 117,982 | |
| 58. | The Losers | The Game Of Life 2 Made Me Regret My Real Life... | 109,605 | |
| 59. | ChilledChaosGAME | I DECIDED TO BE RUTHLESS THIS TIME! (No Time To Relax & Game Of Life 2) | 107,702 | |
| 60. | ChilledChaos | LIFE OF A MOVIE STAR! (The Game of Life | Part 1) | 105,051 | |
| 61. | ChilledChaosGAME | IM STRESSED OUT OF MY MIND! (No Time To Relax & The Game of Life 2) | 105,016 | |
| 62. | Ohmwrecker / Maskedgamer | The Game of Life 2... but sometimes LIFE gives you LEMONS! | 104,249 | |
| 63. | JeromeACE | I Lost My Millions In LIFE - The Game Of Life | JeromeACE | 103,304 | |
| 64. | Sinjin Drowning | Nomnomnom | 96,828 | |
| 65. | Ray Narvaez Jr | Twitch Livestream | The Game of Life 2 w/Chibidoki, Nagzz21 & Axialmatt [PC] | 93,240 | |
| 66. | JeromeACE | I Became An Exotic Bird Watcher In The Game Of Life 2 | 92,861 | |
| 67. | Ray Narvaez Jr | Twitch Livestream | The Game of Life 2 w/Chibidoki & Nagzz21 [PC] | 92,633 | |
| 68. | Verzichten | [FULL ROUND] The Amigops (Sykkuno, Rae, Corpse, and Toast) Plays The Game of Life 2 | Toast in Debt! | 92,561 | Let's Play |
| 69. | fuslie | "SYKKUNO IS CHEATING LIFE" - THE GAME OF LIFE 2 ft. JoblessGarrett, Autumn | 91,401 | |
| 70. | Stumpt | Game of Life 2 - Spooky Board! (4-Player Gameplay) | 91,332 | |
| 71. | ChilledChaosGAME | LIFE IS LIKE A BOX OF DRAW 4's...ITS GONNA HURT! (UNO & A Game of Life) | 88,660 | |
| 72. | ChilledChaosGAME | TAXES & DEATH...! | Chilled, Ze, Smarty & Aphex! (The Game of Life 2) | 87,224 | |
| 73. | JeromeACE | Becoming A Millionaire In The Game Of Life 2 | 82,940 | |
| 74. | PG | The Game of Life 2 w/ ImDontai, Krystalogy, JoJo | 81,897 | Vlog |
| 75. | JeromeACE | My MILLION Dollar Career in The Game Of Life 2 | 81,309 | |
| 76. | K-City Gaming | We Built the SPOOKIEST Family EVER in Game of Life 2! | 80,357 | |
| 77. | ChilledChaos | FIRED FROM MY JOB...AGAIN! (The Game of Life | Part 2) | 76,686 | |
| 78. | JeromeACE | Becoming A Witch In The Game Of Life 2 | 71,670 | |
| 79. | ChilledChaosGAME | ARE YOU MARRIED TO YOUR WORK? (The Game of Life 2) | 69,476 | |
| 80. | Verzichten | [ALL POV] EVERYONE Still Thinks Sykkuno is doing a "TRICK" in The Game of Life 2! | 64,944 | |
| 81. | JeromeACE | No College Challenge In The Game Of Life 2 | 64,513 | |
| 82. | Stumpt | Game of Life 2 - WANDAVISION LAND! (4-Player Gameplay) | 62,457 | |
| 83. | PlayStation | The Game of Life 2 - Launch Trailer | PS5 & PS4 Games | 58,385 | |
| 84. | Stumpt | Stumpt Plays - Home Improvisation - IKEA Simulator! (4 Player Gameplay) | 50,589 | |
| 85. | M&M Gamer92 | PC The Game of Life Full Gameplay | 50,315 | |
| 86. | Stumpt | Boss Defiance - #1 - Reverse CRAWL?! (4 Player Gameplay) | 49,929 | |
| 87. | Stumpt | Game of Life 2 - Winter Wonderland! (4-Player Gameplay) | 49,842 | |
| 88. | Stumpt | Game of Life 2 - AGE OF GIANTS!! (4-Player Gameplay) | 48,445 | |
| 89. | POG Highlights Area | Rae feels passionate about this subject | 48,018 | |
| 90. | Ohmwrecker / Maskedgamer | LIVING MY BEST LIFE... as a SHARK! | The Game of Life 2 (Multiplayer Online!) | 45,843 | |
| 91. | Stumpt | Bomb Bomb! My Friend - FLYING PIGS DROPPING BOMBS! (4 Player Gameplay) | 45,753 | |
| 92. | JeromeACE | How To Win $1,000,00 In Life - The Game Of Life | 39,479 | Guide |
| 93. | Sykkuno VODs – Unofficial | [2021/08/15] casual game with friens (Tricky Towers, THE GAME OF LIFE 2) | 36,757 | |
| 94. | Biffle | My Friends MARRIED My MOM in Game Of Life 2! | 36,661 | |
| 95. | Eclipse and Saturn Show | Game of Life 2 - EARTH'S A BULLY! ft. Lunar and Earth | 36,618 | |
| 96. | Dead Squirrel | TRYING TO WIN THE GAME OF LIFE!!! [GAME OF LIFE 2] w/CARTOONZ, JIHI, ROCKY | 35,097 | |
| 97. | Stumpt | Game of Life 2 - ONLY TIES!! (4-Player Gameplay) | 34,367 | |
| 98. | Dead Squirrel | LIFE IS GETTING CRAZY!!! [GAME OF LIFE 2] w/FRIENDS | 34,262 | |
| 99. | Stumpt | Game of Life 2 - ONLY ROLL HIGH! (3-Player Gameplay) | 34,072 | |
| 100. | ZeRoyalViking | A Life of POOR DECISIONS turned successful | The Game of Life 2 w/ Friends | 32,963 | |
