| 1. |  GameGrumps | Tiny Brains: Tiny Soccer! - PART 1 - Steam Rolled | 567,271 | |
| 2. | Rooster Teeth | How To: Tiny Brains with Joel & Adam | Rooster Teeth | 308,491 | Guide |
| 3. | GameGrumps | Tiny Brains: Ball Challenges! - PART 2 - Steam Rolled | 284,699 | |
| 4. | ChilledChaos | Little Big Planet Meets Portal (Tiny Brains: The Derp Crew - Part 1) | 213,234 | |
| 5. | Stumpt | Stumpt Plays - Tiny Brains - #1 - Pinky and the Brain (4 Player Gameplay) | 211,044 | Let's Play |
| 6. | Geek & Sundry | Tiny Brains Let's Play: Co-Optitude | 115,765 | Let's Play |
| 7. | PlayStation | Tiny Brains Gameplay | 90,765 | Let's Play |
| 8. | PlayStation | Tiny Brains on PS4 | 90,488 | |
| 9. | Stumpt | Tiny Brains: Revisited - #1 - RATS WITH SUPERPOWERS! (4 Player Gameplay) | 88,909 | |
| 10. | ChilledChaos | Radioactive Balls of Science (Tiny Brains: The Derp Crew - Part 2) | 87,654 | |
| 11. | The Completionist | Tiny Brains - I'm IN The Game | 73,730 | Review |
| 12. | Stumpt | Stumpt Plays - Tiny Brains - #2 - BBQ Explosive Chickens | 68,811 | Let's Play |
| 13. | Gagatun | Гагатун и Максим впервые играют в Tiny Brains | 65,647 | |
| 14. | ZeRoyalViking | FOUR BLIND MICE (Tiny Brains w/ The Derp Crew / Facecam Ep. 1) | 62,415 | |
| 15. | Stumpt | Stumpt Plays - Tiny Brains - #4 - Pinky's Revenge (FINAL Episode!) | 62,161 | Let's Play |
| 16. | ChilledChaos | We've Been Betrayed! (Tiny Brains: The Derp Crew - Part 6) | 61,075 | |
| 17. | ChilledChaos | Pinky The Cute Chicken (Tiny Brains: The Derp Crew - Part 3) | 60,884 | |
| 18. | ChilledChaos | Protect the Pink Chicken! (Tiny Brains: The Derp Crew - Part 4) | 58,757 | |
| 19. | Stumpt | Stumpt Plays - Tiny Brains - #3 - FIRE ZE SHRINK LAZER!! | 57,995 | Let's Play |
| 20. | IGN | Tiny Brains Video Review | 57,845 | Review |
| 21. | ChilledChaos | Protect the Scientist and his Balls! (Tiny Brains: The Derp Crew - Part 7) | 49,389 | |
| 22. | GameNews PlayStation | PS4 - Tiny Brains Official Launch Trailer | 43,908 | Preview |
| 23. | TonyPizzaGuy | Tiny Brains - PS4 - Ep. 1 - Of Mice and Men - Co-Op w/ TonyPizzaGuy & Mikey Danger | 38,108 | |
| 24. | Stumpt | Tiny Brains: Revisited - #2 - SAVE PINKY!! (4 Player Gameplay) | 36,981 | |
| 25. | Far Lands or Bust with KurtJMac | Tiny Brains - 01 - Co-op with Chiib, LDShadowLady, & PauseUnpause | 30,605 | |
| 26. | Stumpt | Tiny Brains: Revisited - #3 - DANCE PARTY! (4 Player Gameplay) | 29,128 | |
| 27. | IGN | Your First Look at Tiny Brains for PlayStation 4 | 28,278 | Let's Play |
| 28. | ZeRoyalViking | PROTECT THE CHICKEN (Tiny Brains w/ The Derp Crew / Facecam Ep. 2) | 27,364 | |
| 29. | ZeRoyalViking | MICE INCOMPETENCE (Tiny Brains w/ The Derp Crew / Facecam Ep. 5) | 22,081 | |
| 30. | Far Lands or Bust with KurtJMac | Tiny Brains - 02 - Co-op with Chiib, LDShadowLady, & PauseUnpause | 21,051 | |
| 31. | ZeRoyalViking | CALL 911 (Tiny Brains w/ The Derp Crew / Facecam Ep. 3) | 19,680 | |
| 32. | ZeRoyalViking | THE SCIENTIST (Tiny Brains w/ The Derp Crew / Facecam Ep. 4) | 17,873 | |
| 33. | GaLm | [1] Minuscule Gray Matter (Let's Play Tiny Brains w/ GaLm and the Derp Crew) | 16,419 | Let's Play |
| 34. | ZeRoyalViking | HONEY, I SHRUNK THE SCIENTIST (Tiny Brains w/ The Derp Crew / Facecam Ep. 6) | 16,326 | |
| 35. | ZeRoyalViking | THE FINAL BOSS (Tiny Brains w/ The Derp Crew / Facecam Ep. 8) | 15,915 | |
| 36. | Far Lands or Bust with KurtJMac | Tiny Brains - 03 - Co-op with Chiib, LDShadowLady, & PauseUnpause | 15,903 | |
| 37. | ZeRoyalViking | SLOMOOOOOOOO (Tiny Brains w/ The Derp Crew / Facecam Ep. 7) | 13,802 | |
| 38. | Tango Tek | Tiny Brains #1 - Super Powered Lab Animals! | 13,564 | |
| 39. | Giant Bomb | Tiny Brains: Giant Bomb Quick Look | 11,183 | |
| 40. | 505 Games | Tiny Brains Launch Trailer | 9,689 | Preview |
| 41. | fgw | Tiny Brains - Full Game Playthrough (No Commentary) | 7,372 | Let's Play |
| 42. | GaLm | [2] Minuscule Gray Matter (Let's Play Tiny Brains w/ GaLm and the Derp Crew) | 7,351 | Let's Play |
| 43. | GaLm | [3] Minuscule Gray Matter (Let's Play Tiny Brains w/ GaLm and the Derp Crew) | 6,343 | Let's Play |
| 44. | GaLm | [5] Minuscule Gray Matter (Let's Play Tiny Brains w/ GaLm and the Derp Crew) | 6,303 | Let's Play |
| 45. | Tango Tek | Tiny Brains #2 - Protect Little Pinky! | 6,189 | Let's Play |
| 46. | GaLm | [4] Minuscule Gray Matter (Let's Play Tiny Brains w/ GaLm and the Derp Crew) | 5,811 | Let's Play |
| 47. | TonyPizzaGuy | Tiny Brains - PS4 - Ep. 3 - BIG BALLS - Co-Op w/ TonyPizzaGuy & Mikey Danger | 4,840 | |
| 48. | TonyPizzaGuy | Tiny Brains - PS4 - Ep. 4 - MOUSE TRAP - Co-Op w/ TonyPizzaGuy & Mikey Danger | 4,687 | |
| 49. | Tango Tek | Tiny Brains #5 - Zedaph Cheaterates! | 4,663 | |
| 50. | Tango Tek | Tiny Brains #3 - Gerbil Force Powers?! | 4,619 | Let's Play |
| 51. | TonyPizzaGuy | Tiny Brains - PS4 - Ep. 2 - CHICKS - Co-Op w/ TonyPizzaGuy & Mikey Danger | 4,392 | |
| 52. | Mac A Snack | Tiny Brains Official Ps4 Gameplay | 4,355 | |
| 53. | Tango Tek | Tiny Brains #4 - Mistakes Were Made! | 4,161 | Let's Play |
| 54. | AginoGaming | Tiny Brains- Co-op / Commentary - Part #01 | 4,057 | |
| 55. | 505 Games | Tiny Brains Update Trailer | 3,719 | Vlog |
| 56. | AginoGaming | Tiny Brains- Co-op / Commentary - Part #08 - Final | 2,059 | |
| 57. | Scotty's HD Gaming Channel! | Tiny Brains on PS3 in HD 720p | 1,532 | |
| 58. | TonyPizzaGuy | TINY BRAINS - PS4 - LIVE STREAM W/ MIKEY DANGER | 1,330 | |
| 59. | Hetty | I Am So Tinyy (TINY BRAINS - FIRST IMPRESSIONS) | 1,233 | First Impressions |
| 60. | GameSpot Trailers | Tiny Brains - Teaser Trailer | 1,096 | Preview |
| 61. | AccidentalGrenade | Let's Play "Tiny Brains" on PS4 Part 1 | 1,084 | Let's Play |
| 62. | LioN KoLLA | Tiny Brains PC Gameplay | 1080p | 914 | |
| 63. | AginoGaming | Tiny Brains- Co-op / Commentary - Part #06 | 780 | |
| 64. | AginoGaming | Tiny Brains- Co-op / Commentary - Part #07 | 714 | |
| 65. | Artorigold | Chainsaw Man Chapter 99 - The Chad Yoshida | Live reaction and thoughts from tiny brain | 617 | |
| 66. | AginoGaming | Tiny Brains- Co-op / Commentary - Part #02 | 610 | |
| 67. | AginoGaming | Tiny Brains- Co-op / Commentary - Part #04 | 547 | |
| 68. | AginoGaming | Tiny Brains- Co-op / Commentary - Part #03 | 518 | |
| 69. | AginoGaming | Tiny Brains- Co-op / Commentary - Part #05 | 490 | |
| 70. | ironHEART.tv ツ | Tiny Brains Gameplay Trailer | 459 | Preview |
| 71. | Jed Whitaker | The Talkroom Episode #2: New games, Microtransactions and Tiny Brains Interview | 457 | Show |
| 72. | T1GlistenerElf | "She Really is Your Daughter." | 252 | |
| 73. | Scotty's HD Gaming Channel! | Tiny Brains Gameplay Final Boss Battle and Ending (PS4) | 215 | |
| 74. | cub | Tiny Brains (Video Review) | 213 | Review |
| 75. | SanityUP | Tiny Brains | Smashing Chicks!! - Split the Screen | 120 | |
| 76. | Scotty's HD Gaming Channel! | Tiny Brains Gameplay (PS4) | 99 | |
| 77. | SanityUP | Tiny Brains | We're Good at Shapes - Split the Screen | 87 | |
| 78. | Master Of Chaos | Shoutout Sunday #7 - Grow Your Gaming/Vlog Channel Here! - ''tiny brains'' | 84 | Let's Play |
| 79. | Jason's Gameplay Videos | Tiny Brains - Today's Experiment: Control Mice Tutorial, Puzzles & Tests Mouse Abilities HD Gameplay | 81 | Tutorial |
| 80. | Silvadorkable | Tiny Brains #5 - Save me, cheeses! | 70 | |
| 81. | Gamer ZoneXF | Tiny Brain - Launch Trailer | 64 | |
| 82. | Praisedscooter | Think Fast: Cleverty (Tiny Brains) | 61 | |
| 83. | GotGame | Tiny Brains Preview | 59 | |
| 84. | SanityUP | Tiny Brains | The Abandoned Lab - Split the Screen | 58 | |
| 85. | DoubleBuff | Tiny Brains Part 1 "The Problem Solvers" | 51 | |
| 86. | jakepeter | Tiny Brains Puzzle Fun! | Indie Month Day 27 | 44 | |
| 87. | MikiranPlays | Quick little creepy game to some co-op action with Blue! #GeeksOrder | 44 | |
| 88. | SanityUP | Tiny Brains | Fresh Chicken Wings!! - Split the Screen | 44 | |
| 89. | DoubleBuff | Tiny Brains Part 2 "Fight for the Pink Chick | 43 | |
| 90. | Scotty's HD Gaming Channel! | Tiny Brains Full Game Prologue Gameplay (PS4) | 41 | Vlog |
| 91. | Kevin A. Wright | Tiny Brains Trailer 1080p | 38 | |
| 92. | Daniel Brenner | Tiny Brains Demo Walkthrough Part 1 | 34 | Walkthrough |
| 93. | Popular Geekery | Tiny Brains with Popular Geekery pt2 | 34 | |
| 94. | Popular Geekery | Tiny Brains with Popular Geekery pt1 | 32 | |
| 95. | T1GlistenerElf | 🔴T1Fam Plays Tiny Brains — Co-op Mice are Nice | 27 | Let's Play |
| 96. | Byked Entertainment | "Tiny Dicks" Tiny Brains Gameplay | 24 | |
| 97. | MikiranPlays | More Co-Op Chaos with BlueAquaticsGames and Nitro_GamesYT! #GeeksOrder | 23 | |
| 98. | Daniel Brenner | Tiny Brains Demo Walkthrough Part 3 | 23 | Walkthrough |
| 99. | Game Controller Network | TINY BRAINS DIDN'T WORK SO HERE'S ANOTHER SHORT STREAM | 23 | |
| 100. | Let's Cats | Stories #5: Um, Let's Try Another Destiny – Let's Cats | 22 | |
