Bulletstorm Walkthrough - Act 4 - Chapter 2: Part 3
Full Walkthrough: http://www.gamefront.com/bulletstorm-walkthrough/
Slid under the tree branch and hold LT when that huge mama Maneater pops out of the ground. The trick is to avoid the roots that randomly shoot out and try to strangle you. In order to avoid them, you can double tap A to perform a slide, but holding A down you can do a continuous slide around the perimeter of the area.
Shooting her in the head will do the most damage, but shots to those large glowing membranes will also inflict damage. Once the membranes turn bright orange, just focus on shooting those to destroy them. Do so as quickly as possible because this is how she regenerates and earns back her health.
Just focus on the green membranes now. Once they turn orange again, destroy them as quickly as possible. Following this, the mouth will attempt to attack you. Continue to keep moving at fire shots at the mouth whenever you get a chance.
Once her mouth recoils, show launch a grip of Nom parasites. With her health down about halfway, switch to your sniper and when ever you get a chance, fire a few shots. If you are ever running low on ammo, slid around the perimeter and look for the ammo briefcases.
After all its health has been drained, it will roll out of the ground and attempt to regenerate again. Switch back to your rifle and unload on the orange tentacles. Switch back to your sniper again and fire a few shots to drain its health.
ACHIEVEMENT: Just as before, destroy the orange tentacles as quickly as possible. You'll notice that when she regenerates yet again, her neck will be red. Stick with the rifle and unload on her neck to finally kill her.
Full Walkthrough: http://www.gamefront.com/bulletstorm-walkthrough/