The boss is a giant ogre with hive enemies randomly spawned as adds. The text occasionally reads he's doing something with his stomach...this is a warning the slow buff is coming. For 10 seconds, you won't be able to move. You can shoot and turn around, but you're basically motionless and won't be able to jump away or run from enemy fire. What we quickly learned is to down the hardest hitting adds (like wizards) before the debuff comes. Then just make sure you put something between you and the boss right before the slow debuff... because otherwise his eye laser will kill you while you helplessly stand there. That's the only mechanic to worry about in the entire fight.
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