| 301. | New Champion Bosses - Grinch Krampus and Alien Lokii - The Binding of Isaac Fiend Folio | 25 | Vlog | The Binding of Isaac: Rebirth
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| 302. | Pica Run - The Binding of Isaac Repentance Challenge #41 | 24 | | The Binding of Isaac: Rebirth
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| 303. | Isaaconnect - A New Isaac Game! | 22 | | The Binding of Isaac: Rebirth
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| 304. | Greedier Mode Cutscene - The Binding of Isaac Repentance | 11 | | The Binding of Isaac: Rebirth
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| 305. | Clog Boss Preview - The Binding of Isaac Repentance | 10 | Vlog | The Binding of Isaac: Rebirth
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| 306. | Colostomia Boss Preview - The Binding of Isaac Repentance | 9 | Preview | The Binding of Isaac: Rebirth
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| 307. | Scat Man - The Binding of Isaac Repentance Challenge #36 | 8 | | The Binding of Isaac: Rebirth
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| 308. | Baby Plum Boss Preview - The Binding of Isaac Repentance | 7 | Preview | The Binding of Isaac: Rebirth
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| 309. | Min-Min Boss Preview - The Binding of Isaac Repentance | 7 | Preview | The Binding of Isaac: Rebirth
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| 310. | The Void Cutscene - The Binding of Isaac Repentance | 5 | | The Binding of Isaac: Rebirth
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| 311. | Reap Creep Boss Preview - The Binding of Isaac Repentance | 4 | Preview | The Binding of Isaac: Rebirth
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| 312. | How to Play ISAAC ONLINE and Participate in the Beta Testing | 3 | Tutorial | The Binding of Isaac: Rebirth
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| 313. | The Binding of Isaac Super Bum Transformation in 4K | 3 | | The Binding of Isaac: Rebirth
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| 314. | Intro Cutscene - The Binding of Isaac Repentance | 3 | | The Binding of Isaac: Rebirth
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| 315. | Womb (It Lives) Cutscene - The Binding of Isaac Repentance | 3 | | The Binding of Isaac: Rebirth
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| 316. | The Pile Boss Preview - The Binding of Isaac Repentance | 3 | Preview | The Binding of Isaac: Rebirth
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| 317. | Lil Blub Boss Preview - The Binding of Isaac Repentance | 2 | Preview | The Binding of Isaac: Rebirth
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| 318. | Bumbino Boss Preview - The Binding of Isaac Repentance | 2 | Preview | The Binding of Isaac: Rebirth
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| 319. | Womb (Ipecac) Cutscene - The Binding of Isaac Repentance | 1 | | The Binding of Isaac: Rebirth
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| 320. | Womb (Everything is Terrible) Cutscene - The Binding of Isaac Repentance | 1 | | The Binding of Isaac: Rebirth
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| 321. | Wormwood Boss Preview - The Binding of Isaac Repentance | 1 | Preview | The Binding of Isaac: Rebirth
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| 322. | Chest Cutscene - The Binding of Isaac Repentance | 1 | | The Binding of Isaac: Rebirth
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| 323. | Womb (Dr. Fetus) Cutscene - The Binding of Isaac Repentance | 1 | | The Binding of Isaac: Rebirth
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| 324. | Womb (Noose) Cutscene - The Binding of Isaac Repentance | 1 | | The Binding of Isaac: Rebirth
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| 325. | The Rainmaker Boss Preview - The Binding of Isaac Repentance | 1 | Preview | The Binding of Isaac: Rebirth
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| 326. | Sheol Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 327. | Update v1.7.9 - Full patch notes - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 328. | Womb (Wire Coat Hanger) Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 329. | Epilogue Cutscene - The Binding of Isaac Repentance | 0 | Vlog | The Binding of Isaac: Rebirth
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| 330. | The Most Useless Change to an Item - The Binding of Isaac Repentance Patch Update v1.7.9 | 0 | | The Binding of Isaac: Rebirth
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| 331. | Poor Baby Plum! - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 332. | Cathedral Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 333. | Mega Satan Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 334. | Womb (Eden) Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 335. | Genesis Retake Light (Death Edition) - The Binding of Isaac Repentance Soundtrack | 0 | | The Binding of Isaac: Rebirth
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| 336. | Dark Room Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 337. | Womb (A Quarter) Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 338. | Credits - Outro Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 339. | Womb (Rubber Cement) Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 340. | Womb (???) Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 341. | Greed Mode Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 342. | Womb (Experimental Treatment) Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 343. | Blue Womb Cutscene - The Binding of Isaac Repentance | 0 | | The Binding of Isaac: Rebirth
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| 344. | Item Buffs, Internal Item Descriptions, New Devil Deals, and More! UPDATE v.1.9.7.13 | 0 | | The Binding of Isaac: Rebirth
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| 345. | New Isaac v1.9.7.11 Update-Patch Notes for Repentance+ | 0 | | The Binding of Isaac: Rebirth
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| 346. | The Complete Guide to Tarnished ??? - The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 347. | Repair Machines! The NEW Dad's Toolbox Item in The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 348. | Runic Tablet - NEW MOD - The Binding of Isaac Mod Showcase | 0 | | The Binding of Isaac
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| 349. | NEW Epiphany Item: Relative Robby - The Binding of Isaac Epiphany Item Showcase | 0 | | The Binding of Isaac
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| 350. | They Added an Air Conditioner in The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 351. | Ankle Weights - NEW ITEM in The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 352. | All New GOLDEN TRINKET Effects! The Binding of Isaac Repentance+ Update | 0 | | The Binding of Isaac: Rebirth
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| 353. | The NEW and REWORKED Dimensional Key in The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 354. | NEW Epiphany Item: Fire of Alexandria - The Binding of Isaac Epiphany Item Showcase | 0 | | The Binding of Isaac
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| 355. | New Isaac v1.9.7.10 Update-Patch Notes for Repentance+ | 0 | | The Binding of Isaac: Rebirth
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| 356. | NEW Epiphany Item: Party Popper - The Binding of Isaac Epiphany Item Showcase | 0 | | The Binding of Isaac
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| 357. | The Repentance Plus DLC is HERE! Here are the Release Notes! | 0 | |
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| 358. | The New TARNISHED ISAAC Unlock Cutscene in Epiphany - The Binding of Isaac | 0 | | The Binding of Isaac
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| 359. | BETTER TINTED ROCKS! The New Geocache Item in The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 360. | The Power of Electricity! The New Plasma Ball Item in The Binding of Isaac Epiphany | 0 | | The Binding of Isaac: Rebirth
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| 361. | NEW Epiphany Item: Liquid Nitrogen - The Binding of Isaac Epiphany Item Showcase | 0 | | The Binding of Isaac
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| 362. | New D!Edith ITEM UNLOCKS - The Binding of Isaac Mod Showcase | 0 | | The Binding of Isaac: Rebirth
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| 363. | The Box - A New Item in The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 364. | The PERFECT Diplopia - The Binding of Isaac #shorts | 0 | | The Binding of Isaac: Rebirth
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| 365. | NEW Epiphany Item: Ancient One's Mark - The Binding of Isaac Epiphany Item Showcase | 0 | | The Binding of Isaac
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| 366. | Burning Passion - Heal from Fire Places in Epiphany - The Binding of Isaac | 0 | | The Binding of Isaac: Rebirth
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| 367. | Explore the Red Rooms Easily! The New Doorknob Item in The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 368. | Fruity Rooms - 25 NEW OP ITEMS - The Binding of Isaac Mod Showcase | 0 | | The Binding of Isaac
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| 369. | Tarnished Blue Baby UNLOCKS - The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 370. | How to Use Mods in Repentance+ [AT YOUR OWN RISK!] | 0 | | The Binding of Isaac: Rebirth
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| 371. | How to Unlock Every TARNISHED CHARACTER in Epiphany - The Binding of Isaac | 0 | | The Binding of Isaac: Rebirth
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| 372. | Pocket Active Items! The New Active Sack Item in The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 373. | The NEW Necromancer Transformation in The Binding of Isaac | 0 | | The Binding of Isaac: Rebirth
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| 374. | New Isaac v1.9.7.9 Update-Patch Notes for Repentance+ | 0 | | The Binding of Isaac: Rebirth
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| 375. | NEW Epiphany Item: Giant Puffball - The Binding of Isaac Epiphany Item Showcase | 0 | | The Binding of Isaac
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| 376. | Become DOGMA! The New Mimicry item The Binding of Isaac Epiphany | 0 | | The Binding of Isaac: Rebirth
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| 377. | All 9 Secret Ways of Dying in Epiphany - The Binding of Isaac | 0 | | The Binding of Isaac
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| 378. | The New and REWORKED Tarnished Judas - The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 379. | Stake Your Enemies! The New Wooden Stake Item in The Binding of Isaac Epiphany | 0 | | The Binding of Isaac
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| 380. | All New SOUND EFFECTS! The Binding of Isaac Repentance+ Update | 0 | | The Binding of Isaac: Rebirth
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| 381. | ALL NEW SOUND EFFECTS in the Repentance+ DLC v1.9.7.11 & v1.9.7.12 | 0 | | The Binding of Isaac: Rebirth
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| 382. | NEW Epiphany Item: Brain in a Jar - The Binding of Isaac Epiphany Item Showcase | 0 | | The Binding of Isaac
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| 383. | I Made an Isaac Themed Guessing Game - Who's That Isaac?! | 0 | | The Binding of Isaac: Rebirth
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| 384. | NEW Epiphany Item: Promo Toy - The Binding of Isaac Epiphany Item Showcase | 0 | | The Binding of Isaac
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