| 1. |  Jaba Play | 46,873 | ANNO: Mutationem - All Bosses + Ending [No Damage] | 52:20 |
| 2. | Pat Stares At | 6,932 | Pat Stares At Anno Mutationem! #Sponsored | 4:08:38 |
| 3. | Dean Lofi Plays | 3,715 | ANNO: Mutationem First Impression - Is It Worth Playing? | 28:38 |
| 4. | Just3c | 3,066 | Trying out new Cyberpunk game a bit | 26:09 |
| 5. | Ran 💜 | 2,169 | Priorities #shorts #vtuber | 0:14 |
| 6. | Lucy First | 867 | Anno Mutationem | I Unlocked 100% Achievements | 36:37 |
| 7. | Johnald Games | 230 | Anno: Mutationem #annomutationem #indiegame #indiegames #scifigame | 0:00 |
| 8. | Blazing Glaceon | 194 | ANNO: Mutationem ~ The Mysterious Game Console | 1:11:17 |
| 9. | Xbox Stadium | 174 | ANNO: Mutationem | Xbox Series X Gameplay | First Look | 1:22:53 |
| 10. | Mike Tessier | 147 | ANNO : MUTATIONEM - PARTIE - 19 - | 29:13 |
| 11. | FeralLam | 141 | Suffer, like G did | Anno finale | 57:27 |
| 12. | Jaded Hero Gaming | 137 | Anno Mutationem Gameplay - PC (MAX Settings) | Bulldozer Boss | 6:11 |
| 13. | Gaming Plus TV | 122 | ANNO: Mutationem | Official Launch Walkthrough PART 1 (PC) Gameplay @ 2K 60 fps | 1:00:59 |
| 14. | Szar | 121 | Cyberpunk | ANNO Mutationem | Indie Game | 16:02 |
| 15. | shadicnion500 | 112 | Anno | Mutationem so is the big triangle the villan orrrrrr Part 6 | 4:16:54 |
| 16. | The Collecting Confidant | 100 | 002: ANNO: Mutationem (Limited Run Preview) | 7:45 |
| 17. | Galatea Iris Ch. | 86 | Propaganda for the Greatsword Agenda™ | ANNO: Mutationem (#4) | 2:05:49 |
| 18. | Xenonean | 77 | The Final Battle!- ANNO: Mutationem | Part END| Playthrough | 0:00 |
| 19. | Lintello Brume | 67 | Anno Mutationem Demo First Playthrough | 0:00 |
| 20. | TheBooneGuy | 47 | ANNO: Mutationem (Ps4) - 2nd Play/Bartending/Combat/Ping Ping Arcade | 0:00 |
| 21. | Fiera_13 | 47 | Final Boss - ANNO Mutationem Part 6 | 1:30:36 |
| 22. | reallyreally longathon | 43 | ANNO: Mutationem by mash - RRLAT8 Christmas bonus | 0:00 |
| 23. | Kara Unscripted | 36 | ANNO: Mutationem Let's Play Pt 1 | Being the BEST Bartender | 49:28 |
| 24. | OptimalPower | 34 | ANNO: Mutationem - 7 | 2:11:21 |
| 25. | Xe ph | 30 | ANNO: Mutationem #11 | 43:09 |
| 26. | Xagatal | 28 | Anno : Mutationem [!] pharoah robot | 0:00 |
| 27. | Old World Gamer | 22 | Retro Indie Pixels Podcast - Episode 050: My Wallet Hurts | 2:57:22 |
| 28. | Midnights in Valhalla | 13 | IT HAPPENED AGAIN...HOLY SHI- | 3:34:40 |
| 29. | CodeChannel | 10 | ANNO: Mutationem (Demo Play) Ep.X -- Stylishpunk 2D | 50:18 |
| 30. | Ginger Jester | 6 | www.uhoh.com | Anno Mutationem | 28:04 |
| 31. | Maclintok | 6 | ANNO: Mutationem - Live Stream - Getting a bit Lost? | 2:10:47 |
| 32. | Litl Clutch (Derek) | 6 | ANNO: Mutationem, Very cool looking action game! | 1:04:39 |
| 33. | CanadianCJ | 6 | ANNO Mutationem Official Gameplay Trailer Summer of Gaming 2021 | 2:43 |
| 34. | DrinPixeled VODs | 5 | What even...? - ANNO: Mutationem, Day 3 | 2:48:31 |
| 35. | CGMagazine | 4 | ANNO: Mutationem - Gameplay Trailer | Summer of Gaming 2021 | 2:43 |
| 36. | LordLan | 3 | ANNO: Mutationem (first 30min gameplay) | 0:00 |
| 37. | ss videos | 1 | Anno Mutationem - new trailer 2023 | 1:10 |
| 38. | vernatube | 1 | robo-cult and rampaging pixels | 2:14:21 |
| 39. | Tong Zou | 0 | Let's play ANNO: Mutationem (2022, PC) | 43:40 |
| 40. | aaymon86 | 0 | ANNO: Mutationem - Checking this out | 0:00 |
