| Medal of Honor: Heroes 2 (2007) | 10,083,671 | 2,211 |
| Medal of Honor: Infiltrator (2003) | 812,438 | 418 |
| Medal of Honor: Pacific Assault (2004) | 32,750,815 | 7,493 |
| Medal of Honor: Rising Sun (2003) | 11,537,808 | 3,024 |
| Medal of Honor: Underground (2000) | 18,513,078 | 8,585 |
| Medal of Honor: Vanguard (2007) | 10,279,021 | 2,480 |
| Medal of Honor: Warfighter (2012) | 173,637,885 | 30,943 |
| Medarot (1997) | 3,015,870 | 274 |
| Medarot 8 (2014) | 6,023 | 9 |
| Medarot 9 Kabuto Version (2015) | 142,556 | 206 |
| Medarot DS Kabuto/Kuwagata (2010) | 35,510 | 22 |
| Medetashi Medetashi (2026) | 0 | 0 |
| Medi-Cooker (2025) | 0 | 0 |
| Medic: Pacific Corpsman (2021) | 143,107 | 18 |
| Medical Diagnostic Simulator (2024) | 805 | 1 |
| Medieval (2009) | 153,563,317 | 7,927 |
| Medieval Alchemist (2022) | 83,176 | 6 |
| Medieval Apocalypse (2024) | 114,609 | 29 |
| Medieval Battle: Europe (2018) | 1,060 | 11 |
| Medieval Battlefields (2016) | 12,355 | 36 |
| Medieval Battlegrounds (2022) | 679 | 5 |
| Medieval Chaos (2024) | 126,818 | 6 |
| Medieval Conquest (2004) | 77,076 | 110 |
| Medieval Crafter: Blacksmith (2025) | 461,904 | 242 |
| Medieval Defenders (2016) | 74,087 | 256 |
| Medieval Delivery (2023) | 17,005 | 96 |
| Medieval Dynasty (2021) | 183,408,697 | 108,707 |
| Medieval Engineers (2015) | 40,889,367 | 5,267 |
| Medieval Frontiers (2026) | 697 | 4 |
| Medieval Games (2009) | 1,865,279 | 239 |
| Medieval Halloween VR (2025) | 0 | 0 |
| Medieval Hero (2021) | 498 | 5 |
| Medieval Heroes Gold Hunt (2024) | 0 | 0 |
| Medieval II: Total War (2006) | 495,486,236 | 125,445 |
| Medieval Kingdom Wars (2019) | 3,159,317 | 424 |
| MEDIEVAL KNIGHTMARE (2022) | 74,345 | 6 |
| Medieval Lords: Build, Defend, Expand (2004) | 9,665 | 13 |
| Medieval Lords: Soldier Kings of Europe (1991) | 186 | 3 |
| Medieval Machines Builder (2024) | 5,921,012 | 481 |
| Medieval Mayhem (2006) | 93,377 | 167 |
| Medieval Moves: Deadmund's Quest (2011) | 2,084,705 | 228 |
| Medieval Questionnaire (2024) | 2 | 1 |
| Medieval Remembrance (2023) | 0 | 0 |
| Medieval Shop Simulator (2025) | 0 | 0 |
| Medieval Shopkeeper Simulator (2018) | 890,285 | 135 |
| Medieval StartUp (2025) | 0 | 0 |
| Medieval Steve (2018) | 371 | 7 |
| Medieval Total War XL (2004) | 835 | 2 |
| Medieval Trader Simulator (2021) | 2,227,290 | 300 |
| Medieval Warriors (1991) | 1,337,150 | 86 |
| Medieval: Total War (2002) | 10,041,727 | 3,499 |
| Medievalien (2021) | 45,708 | 36 |
| MediEvil (1998) | 23,320,363 | 15,034 |
| MediEvil (2019) | 39,721,299 | 25,238 |
| MediEvil 2 (2000) | 6,215,130 | 4,665 |
| MediEvil: Resurrection (2005) | 4,045,798 | 3,026 |
| Mediterranea Inferno (2023) | 20,696 | 67 |
| The Medium (2021) | 171,837,648 | 52,813 |
| Medusa Frontier (2022) | 463 | 1 |
| Medusa's Labyrinth (2016) | 1,184,794 | 507 |
| Meduziak (2023) | 517 | 11 |
| Meegah Mem 2 (2019) | 0 | 0 |
| Meeple Station (2019) | 7,732,377 | 573 |
| Meer's: Escape (2023) | 0 | 0 |
| Meerca Chase II (2005) | 5,322 | 3 |
| Meet Me (2008) | 4,365,396 | 302 |
| Meet me at NooN (2022) | 243,583 | 109 |
| Meet My Teacher (2024) | 267 | 1 |
| Meet the Robinsons (2007) | 10,294,143 | 1,224 |
| Meet Your Maker (2023) | 14,805,391 | 8,782 |
| Meg's Monster (2023) | 350,623 | 577 |
| MEG: RVO (2013) | 7,105 | 2 |
| Mega Apocalypse (1987) | 26,609 | 61 |
| Mega Blast (1995) | 188,737 | 38 |
| Mega City Force (2023) | 7,494 | 18 |
