| MySims Racing (2009) | 2,144,667 | 928 |
| MySims SkyHeroes (2010) | 973,556 | 395 |
| Myst (1993) | 23,654,469 | 5,336 |
| Myst III: Exile (2001) | 3,133,816 | 1,777 |
| Myst IV: Revelation (2004) | 3,688,455 | 1,622 |
| Myst Online: Uru Live (2007) | 744,944 | 370 |
| Myst V: End of Ages (2005) | 1,094,051 | 794 |
| MyStar (2019) | 32,875 | 5 |
| Mystaria: The Realms of Lore (1995) | 246,891 | 265 |
| Mystereet: Fukagyaku Sekai no Tantei Shinshi (2004) | 12,639 | 20 |
| Mysteria of the World: The forest of Death (2022) | 378 | 2 |
| Mysteria ~Occult Shadows (2020) | 253,452 | 252 |
| Mysteries & Nightmares: Morgiana (2015) | 74,611 | 31 |
| The Mysteries of Baroque (2018) | 964 | 4 |
| Mysteries Of Darkness (2022) | 551 | 11 |
| Mysteries Of FangClaw (2025) | 0 | 0 |
| Mysteries of Neverville: The Runestone of Light (2018) | 0 | 0 |
| Mysteries of Old Tokyo (2026) | 18 | 2 |
| Mysteries of Perception (2025) | 192 | 8 |
| Mysteries of Shaola: The Cave (2022) | 0 | 0 |
| Mysteries of the Mind: Coma (2012) | 8,738 | 19 |
| Mysteries of the Undead (2019) | 132,102 | 166 |
| Mysterious Adventure of Michael (2017) | 35,202 | 6 |
| The Mysterious Cities of Gold: Secret Paths (2013) | 506,666 | 142 |
| Mysterious Journey II (2003) | 77,770 | 86 |
| The Mysterious Murasame Castle (1986) | 1,625,303 | 648 |
| Mysterious Mystery, EP 1: The Duo Dilemma (2025) | 11 | 1 |
| Mysterious Place (2023) | 282,972 | 88 |
| Mysterious Space (2015) | 111,060 | 17 |
| Mysterious Stars: A Fairy Tale (2012) | 0 | 0 |
| Mysterious Stars: The Samurai (2012) | 0 | 0 |
| Mysterious Stars: The Singer (2012) | 0 | 0 |
| The Mysterious Thief; Forget Me Not (2025) | 120 | 5 |
| Mysterium (1991) | 21,959,987 | 624 |
| Mystery Agency: Visions of Time (2011) | 386 | 3 |
| Mystery at Grand Fir Village (2023) | 25 | 1 |
| Mystery at Morgoth (2023) | 289 | 7 |
| Mystery Boxes (2025) | 11,112,579 | 141 |
| Mystery Case Files: 13th Skull (2010) | 2,002,245 | 678 |
| Mystery Case Files: A Crime in Reflection (2023) | 26,823 | 110 |
| Mystery Case Files: Agent X (2008) | 6,512 | 3 |
| Mystery Case Files: Black Crown (2019) | 388,925 | 190 |
| Mystery Case Files: Broken Hour (2016) | 0 | 0 |
| Mystery Case Files: Crossfade (2020) | 94,031 | 122 |
| Mystery Case Files: Dire Grove (2009) | 1,398,149 | 412 |
| Mystery Case Files: Dire Grove, Sacred Grove (2014) | 247,869 | 247 |
| Mystery Case Files: Escape from Ravenhearst (2011) | 1,382,629 | 318 |
| Mystery Case Files: Fate's Carnival (2013) | 516,765 | 335 |
| Mystery Case Files: Huntsville (2005) | 226,818 | 331 |
| Mystery Case Files: Incident at Pendle Tower (2021) | 67,769 | 117 |
| Mystery Case Files: Key to Ravenhearst (2015) | 653,007 | 266 |
| Mystery Case Files: Madame Fate (2007) | 613,598 | 469 |
| Mystery Case Files: MillionHeir (2008) | 110,345 | 101 |
| Mystery Case Files: Moths to a Flame (2019) | 119,643 | 247 |
| Mystery Case Files: Prime Suspects (2006) | 191,742 | 269 |
| Mystery Case Files: Ravenhearst (2006) | 1,051,708 | 1,116 |
| Mystery Case Files: Ravenhearst Unlocked (2015) | 465,172 | 249 |
| Mystery Case Files: Return to Ravenhearst (2008) | 3,539,662 | 364 |
| Mystery Case Files: Rewind (2018) | 154,391 | 135 |
| Mystery Case Files: Shadow Lake (2012) | 508,632 | 310 |
| Mystery Case Files: Spirits of Blackpool (2013) | 6,947 | 1 |
| Mystery Case Files: The Black Veil (2017) | 318,841 | 266 |
| Mystery Case Files: The Countess (2018) | 98,301 | 202 |
| Mystery Case Files: The Dalimar Legacy (2023) | 36,426 | 133 |
| Mystery Case Files: The Harbinger (2020) | 359,538 | 171 |
| Mystery Case Files: The Last Resort (2022) | 49,916 | 119 |
| Mystery Case Files: The Malgrave Incident (2011) | 0 | 0 |
| Mystery Case Files: The Revenant's Hunt (2017) | 114,377 | 159 |
| Mystery Case Files: The Riddle of Mrs. Bishop (2024) | 89,407 | 98 |
| Mystery Castle: The Mirror's Secret (2015) | 53,978 | 43 |
| Mystery Chronicle: One Way Heroics (2012) | 89,262 | 209 |
| Mystery Chronicles: Murder Among Friends (2008) | 30,266 | 6 |
| Mystery Circle (1992) | 5,899 | 17 |
| Mystery Cookbook (2008) | 17,584 | 32 |
| Mystery Cruise (2010) | 19,714 | 20 |
