| MainFrames (2025) | 506,303 | 137 |
| Mainichi Issho (2006) | 69,692 | 17 |
| Mainlining (2017) | 141,489 | 149 |
| Maintenance Required (2025) | 354,864 | 35 |
| Maison Ikkoku: Kanketsuhen (1988) | 31,239 | 91 |
| Maitetsu (2018) | 113,628 | 147 |
| Maitetsu:Last Run!! (2020) | 21,475 | 91 |
| Maize (2016) | 19,934,742 | 1,979 |
| Maize Mace Maze (2025) | 1 | 2 |
| The Majesti (2021) | 88,978 | 4 |
| Majestic (2001) | 20,730 | 56 |
| Majestic Nights (2014) | 48,987 | 47 |
| Majesty 2: The Fantasy Kingdom Sim (2009) | 3,722,428 | 2,493 |
| The Majesty of Colors (2008) | 30,751 | 47 |
| Majesty: The Fantasy Kingdom Sim (2000) | 2,098,044 | 1,327 |
| Majesty: The Northern Expansion (2001) | 27,487 | 82 |
| Majik (1990) | 7,657,549 | 62 |
| Majin and the Forsaken Kingdom (2010) | 3,014,242 | 1,471 |
| Majin Bone (2014) | 4,397 | 5 |
| Majin Tensei (1994) | 1,001,971 | 1,164 |
| Majin Tensei II: Spiral Nemesis (1995) | 200,660 | 589 |
| Majokko Daisakusen: Little Witching Mischiefs (1999) | 60,699 | 63 |
| Major Havoc (1983) | 40,387 | 116 |
| Major League Baseball (1988) | 4,305,979 | 472 |
| Major League Baseball 2K10 (2010) | 2,027,343 | 724 |
| Major League Baseball 2K11 (2011) | 3,191,717 | 466 |
| Major League Baseball 2K12 (2012) | 3,780,206 | 872 |
| Major League Baseball 2K5 (2005) | 149,891 | 263 |
| Major League Baseball 2K6 (2006) | 244,471 | 144 |
| Major League Baseball 2K7 (2007) | 558,407 | 261 |
| Major League Baseball 2K8 (2008) | 248,683 | 216 |
| Major League Baseball 2K8 Fantasy All-Stars (2008) | 5,686 | 12 |
| Major League Baseball 2K9 (2009) | 1,338,904 | 202 |
| Major League Baseball 2K9 Fantasy All-Stars (2009) | 1,777 | 5 |
| Major League Baseball Featuring Ken Griffey Jr. (1998) | 425,649 | 336 |
| Major League Eating: The Game (2008) | 8,965 | 14 |
| Major Mayhem (2011) | 4,714,126 | 1,239 |
| Major Mayhem 2 (2018) | 3,381,881 | 1,597 |
| Major Minor's Majestic March (2009) | 102,073 | 35 |
| Major Motion (1986) | 7,082 | 17 |
| Major Stryker (1993) | 46,462 | 133 |
| Major Title (1990) | 78,577 | 52 |
| Major's Heart (2024) | 8 | 1 |
| The Majors: Pro Baseball (1992) | 18,170 | 58 |
| Major\Minor (2016) | 184,799 | 319 |
| Majotori (2017) | 16,934,604 | 919 |
| Majula Frontier (2018) | 1,057 | 7 |
| Makai Hakkenden Shada (1989) | 260,026 | 36 |
| Makai Kingdom: Chronicles of the Sacred Tome (2005) | 464,823 | 602 |
| Makai Kingdom: Reclaimed and Rebound (2022) | 20,728 | 102 |
| Makai Prince Dorabocchan (1990) | 24,339 | 48 |
| Makai Wars (2018) | 141,934 | 177 |
| Makaimura for WonderSwan (1999) | 393,083 | 77 |
| Make 10: A Journey of Numbers (2007) | 8,773 | 12 |
| Make A Jigsaw Puzzle (2018) | 136,373 | 19 |
| Make America Great Again: The Trump Presidency (2016) | 65,389 | 39 |
| Make It In Time (2022) | 63,505 | 24 |
| Make It Rain: The Love of Money (2014) | 615,476 | 43 |
| Make Love Not War (2022) | 62,701 | 49 |
| Make My Video: Marky Mark and the Funky Bunch (1992) | 196,174 | 32 |
| Make Route (2018) | 2,706 | 3 |
| Make Sail (2018) | 506,197 | 104 |
| Make Them Walk (2023) | 174 | 1 |
| Make Trax (1981) | 224,669 | 123 |
| Make Your Own Murder Party (1986) | 646 | 2 |
| Maken Shao: Demon Sword (2001) | 108,342 | 111 |
| Maken X (1999) | 492,544 | 616 |
| Maken-shi Sara (2021) | 0 | 0 |
| The Maker's Eden (2014) | 134,261 | 45 |
| Maki: Paw of Fury (2024) | 11,922 | 72 |
| MAKIBISHI COMIC (2024) | 0 | 0 |
| Making History II: The War of the World (2010) | 191,659 | 106 |
| Making History: The Calm and the Storm Gold Edition (2015) | 31,999 | 1 |
| Making History: The Great War (2014) | 454,250 | 253 |
| Making History: The Second World War (2018) | 107,481 | 54 |
