| Run Like Hell (2002) | 1,772,060 | 440 |
| Run Little Hero (2021) | 223 | 4 |
| Run of Life (2021) | 108,927,843 | 4,983 |
| Run Or Boom (2022) | 16 | 2 |
| RUN OR FIGHT (2020) | 89 | 5 |
| Run Prop, Run! (2021) | 1,219,272 | 153 |
| Run Rabbit Run (2016) | 746,084 | 109 |
| Run Roo Run (2012) | 204,420 | 28 |
| Run Saber (1993) | 2,939,882 | 769 |
| Run TavernQuest (2026) | 0 | 0 |
| Run The Gauntlet (1989) | 1,447,075 | 199 |
| RUN! GRANDPA! RUN! (2020) | 1,443 | 10 |
| Run4YourLight (2022) | 0 | 0 |
| RUN: The world in-between (2022) | 64,451 | 211 |
| Runa Illustra (2025) | 0 | 0 |
| Runabout (1997) | 306,895 | 96 |
| Runabout 2 (1999) | 155,401 | 189 |
| Runabout 3: Neo Age (2002) | 180,860 | 113 |
| Runabout 3D: Drive Impossible (2012) | 10,230 | 9 |
| Runaway 2: The Dream of the Turtle (2006) | 744,713 | 1,231 |
| Runaway Animals (2022) | 124,803 | 26 |
| Runaway, A Road Adventure (2007) | 119,936 | 253 |
| Runaway, The Dream of The Turtle (2007) | 141,688 | 102 |
| Runaway: A Road Adventure (2001) | 1,029,388 | 1,448 |
| Runaway: A Twist of Fate (2009) | 792,035 | 816 |
| Runbow (2015) | 17,671,794 | 1,242 |
| Rune (2000) | 1,885,814 | 962 |
| Rune Bender VR (2024) | 240 | 2 |
| Rune Classic (2012) | 506,431 | 605 |
| Rune Coliseum (2024) | 220,966 | 122 |
| Rune Defender: Dwarven Defense (2025) | 0 | 0 |
| Rune Dice (2026) | 850,085 | 309 |
| Rune Factory 2: A Fantasy Harvest Moon (2008) | 1,619,370 | 1,782 |
| Rune Factory 3 Special (2023) | 1,239,857 | 1,798 |
| Rune Factory 3: A Fantasy Harvest Moon (2009) | 5,277,683 | 4,488 |
| Rune Factory 4 (2012) | 26,487,636 | 13,379 |
| Rune Factory 5 (2021) | 23,973,758 | 16,790 |
| Rune Factory Frontier (2008) | 5,305,760 | 3,082 |
| Rune Factory: A Fantasy Harvest Moon (2006) | 18,610,030 | 10,945 |
| Rune Factory: Guardians of Azuma (2025) | 35,297 | 142 |
| Rune Factory: Tides of Destiny (2011) | 5,891,231 | 2,814 |
| Rune Gate (2024) | 188,319 | 43 |
| Rune Knights (2020) | 7,969,319 | 1,225 |
| Rune Legend (2011) | 29,086 | 23 |
| Rune Rhythm Realm (2026) | 0 | 0 |
| Rune: Gold (2001) | 12,826 | 51 |
| Runeblight (2026) | 0 | 0 |
| Runeborn (2025) | 158,142 | 78 |
| Runeflame (2024) | 23 | 1 |
| Runehaven (2025) | 13,161 | 30 |
| Runemancer (2023) | 69 | 2 |
| The Runemaster's Diary (2023) | 113 | 1 |
| Runeroots TD (2024) | 27,717 | 16 |
| Runers (2014) | 486,978 | 279 |
| Runes of Aereal (2024) | 2,975 | 39 |
| Runes of Avalon - Path of Magic (2017) | 0 | 0 |
| Runes of Avalon 2 (2008) | 1,395 | 6 |
| Runes of Magic (2009) | 12,113,933 | 4,655 |
| Runes of Pandemonium (2022) | 64 | 3 |
| Runes: The Forgotten Path (2018) | 288,865 | 45 |
| RuneScape (2001) | 1,011,939,521 | 79,242 |
| RuneScape: Dragonwilds (2025) | 17,364,698 | 5,901 |
| Runespell: Overture (2011) | 808,943 | 52 |
| Runestone Keeper (2015) | 160,862 | 247 |
| Runestrike CCG (2021) | 50,115 | 124 |
| Runeverse (2022) | 36,436 | 77 |
| Runeyana (2017) | 35,032 | 19 |
| RUNGORE (2024) | 1,074,787 | 815 |
| RunGunJumpGun (2016) | 273,752 | 123 |
| Runi's Math Castle (2024) | 24 | 3 |
| Runic Prophecy (2027) | 0 | 0 |
| Runic Relay: The Trials (2024) | 361 | 10 |
| Runic Survivor (2022) | 165,300 | 42 |
| RunMan Turbo (2024) | 7,097 | 6 |
| RunMan's Monster Fracas (2005) | 2,361 | 1 |
