| Umpire Simulator (2018) | 359 | 1 |
| UMS II: Nations at War (1990) | 1,068 | 6 |
| Umurangi Generation (2020) | 1,040,266 | 636 |
| Un Juego de Huevos (2010) | 26,083 | 8 |
| Un pas fragile (2019) | 253,927 | 50 |
| The Un-BEATable Game (2023) | 7,067,770 | 32 |
| Unalive (2017) | 214,982 | 94 |
| Unarmed Area (2021) | 0 | 0 |
| Unavailed (2023) | 4,938 | 17 |
| Unavowed (2018) | 1,066,318 | 1,861 |
| Unaware (2023) | 849,709 | 125 |
| Unaware in The City (2024) | 1,350 | 2 |
| Unbeatable (2021) | 35,137,741 | 2,490 |
| Unblock Me (2009) | 102,574 | 320 |
| Unblock Me Car (2021) | 1,695 | 451 |
| Unblocking (2022) | 66,495 | 26 |
| Unbound Saga (2009) | 195,179 | 144 |
| Unbound: Worlds Apart (2021) | 1,437,175 | 2,243 |
| Unbox (2016) | 40,505,447 | 1,647 |
| Unbox: Newbie's Adventure (2016) | 2,348,135 | 548 |
| The Unbreakable Gumball (2022) | 38,112 | 6 |
| Unbuild (2021) | 2,307 | 13 |
| Uncanny Valley (2015) | 4,350,298 | 707 |
| Uncanny Valley (2017) | 8,708,194 | 318 |
| The Uncanny X-Men (1989) | 8,127,383 | 3,080 |
| The Uncertain: Last Quiet Day (2016) | 1,049,665 | 1,296 |
| The Uncertain: Light At The End (2020) | 1,182,967 | 1,743 |
| Unchained Blades (2011) | 674,640 | 230 |
| Uncharted 2: Among Thieves (2009) | 334,411,537 | 165,895 |
| Uncharted 3: Drake's Deception (2011) | 552,561,706 | 173,220 |
| Uncharted 4: A Thief's End (2016) | 2,264,096,592 | 693,717 |
| Uncharted Lands: Beginning (2023) | 0 | 0 |
| Uncharted Ocean (2019) | 52,954 | 99 |
| Uncharted Space - project 3062 (2022) | 0 | 0 |
| Uncharted Tides: Port Royal (2019) | 486,972 | 339 |
| Uncharted Waters (1990) | 894,968 | 448 |
| Uncharted Waters (1991) | 320,610 | 223 |
| Uncharted Waters 2: New Horizons (1993) | 187,202 | 129 |
| Uncharted Waters II: New Horizons (1993) | 3,657,668 | 1,045 |
| Uncharted Waters Online (2004) | 4,015,278 | 3,079 |
| Uncharted Waters Online (2010) | 1,349,771 | 126 |
| Uncharted Waters Origin (2023) | 594,944 | 836 |
| Uncharted Waters VI (2019) | 262,683 | 111 |
| Uncharted Waters: New Horizons (1994) | 915,159 | 639 |
| Uncharted: Drake's Fortune (2007) | 208,992,092 | 124,239 |
| Uncharted: Fight for Fortune (2012) | 365,716 | 108 |
| Uncharted: Fortune Hunter (2016) | 1,263,908 | 564 |
| Uncharted: Golden Abyss (2011) | 35,879,241 | 4,114 |
| Uncharted: The Lost Legacy (2017) | 358,460,408 | 134,396 |
| Unclaimed World (2016) | 123,413 | 85 |
| Uncle Chop's Rocket Shop (2024) | 1,222,066 | 746 |
| Uncle Henry's Playhouse (1996) | 954 | 3 |
| Uncle Kenny The Game (2023) | 222 | 4 |
| Uncle Nook's Survivors (2025) | 73 | 4 |
| Uncle Unco (2024) | 1 | 1 |
| Uncle's Basement (2024) | 494,177 | 77 |
| The Unclogging: An Unsanitary Saga (2017) | 0 | 0 |
| Uncolored Bob II (2021) | 121 | 4 |
| Unconnected Marketeers (2021) | 9,017,420 | 2,587 |
| Unconventional Warfare (2022) | 225,526 | 71 |
| Uncover the Smoking Gun (2024) | 617,020 | 90 |
| Uncraft World (2015) | 3,377,644 | 119 |
| Uncrowded (2015) | 497,054 | 17 |
| UNCULT (2024) | 1,526 | 3 |
| UNCURSED (2025) | 130,471 | 125 |
| Undarkened: Revival (2022) | 0 | 0 |
| Undaunted Normandy (2023) | 118,289 | 84 |
| Undawn (2023) | 4,159,938 | 2,090 |
| Undead Battle Royale (2021) | 20,270 | 24 |
| Undead Bowling (2013) | 26,199 | 17 |
| Undead Citadel (2023) | 1,510,843 | 775 |
| Undead City (2024) | 339,654 | 223 |
| Undead Darlings ~no cure for love (2020) | 28,553 | 69 |
| Undead Development (2021) | 279,109 | 1 |
| Undead Horde (2019) | 5,196,927 | 1,830 |
