| 2023-06-14 |  RetroJimmyX | 724 | Defense Grid 2 | 57:32 |
| 2023-01-03 | No Commentary Gaming by Igniseus | 132 | Defense Grid 2 | Part 18 playthrough gameplay | no commentary | Xbox Series X | 37:28 |
| 2022-08-18 | Rick Plays TD Games | 32 | Defense Grid 2 Backlash Elite | 14:37 |
| 2022-05-01 | Steves On YouTube | 105 | Defence Grid 2, Mission 2 - PC, Gameplay (No Commentary) | 17:30 |
| 2021-06-24 | GreyMack | 455 | Defense Grid 2 // Revisited - Chapter 5 (FINAL) | 1:01:25 |
| 2021-02-15 | Water Fist Saga 2017 | 22 | Defense Grid 2 ps4 | 11:43:56 |
| 2020-12-04 | GamePadStreaming | 132 | Lucky Dip #3 - 2020 12 03 - Defense Grid 2, Call of Cthulhu, Grim Fandango, Yakuza Kiwami 2 | 2:30:06 |
| 2020-03-23 | BlueGoblinKing | 118 | Defend against the alien hoard - Defence Grid 2 | 21:05 |
| 2019-11-29 | UltraViolet | 123 | Defense Grid 2: Overlook (Frozen Core. Elite difficulty) | 16:00 |
| 2019-02-16 | Nintendo Tracker | 370 | Defense Grid 2 - Nintendo Switch | 1:14 |
| 2019-02-12 | Multiplayer Media | 6,000 | Let's Try Defense Grid 2 (Nintendo Switch!) | 16:09 |
| 2019-01-31 | KlingonGamerYT | 13,900 | Defense Grid 2 - Nintendo Switch (Price & Trailer) | 1:12 |
| 2018-06-14 | RaMarcus | 18,000 | Oculus Go // Live Stream / Defence Grid 2 / Viral / Face your Fears | 1:33:13 |
| 2018-04-10 | X35 Earthwalker | 505 | The best defence. The ultimate defence | Defense Grid 2 | 13:39 |
| 2017-12-06 | MAXTGGAMING | 332 | Turrets vs Aliens! | 17:08 |
| 2017-06-14 | Paradise Decay | 27,100 | 👀➦VR | MY FAVOURITE 'TD' GAME IN VR! - DEFENSE GRID 2 (With Commentary) | Oculus | GTX 1060 | 31:33 |
| 2017-05-04 | ilRASli | 1,280 | Defense Grid 2 - Building Towers Trophies | 2:48 |
| 2017-02-26 | Martin Risby | 3,960 | Impossible Suspension, We'll See | Defense Grid 2: Enhanced VR Edition | Level 3 Elite | Oculus Rift | 12:58 |
| 2016-06-03 | DXS | 7,850 | Defense Grid 2 - Siege Breaker Achievement guide | 15:55 |
| 2016-06-01 | TheSyncz | 358 | Game Week - Defense Grid 2 - (Episode 16) Xbox One | 21:45 |
| 2016-05-06 | starfighter141 | 104 | D E F E N C E . G R I D 2 - THE FINAL CHAPTER WALKTHROUGH | 1:11:32 |
| 2016-05-01 | Rampage iRonikz | 10,400 | Defence Grid 2 Gameplay ENJOY !!! | 7:29 |
| 2015-08-15 | Stuart J 1210 | 644 | PS4 Defense Grid 2 | 8:51 |
| 2015-06-23 | Dexter Manning | 256,000 | JORDAN GETS REKT | Defense grid 2 | 13:03 |
| 2015-06-18 | baggiobertie | 160 | Defense Grid 2 Coop First Play with Costello | 35:54 |
| 2015-02-08 | channel frosty_bonz | 477 | Dg2 Defense Grid 2 Steam Gift | 4:32 |
| 2014-12-22 | Mellow Gaming | 1,240 | Defense Grid 2 - 60fps - Mellow Gaming | 30:55 |
| 2014-11-01 | Frazzz | 79,100 | Defense Grid 2 Bonus Video 100 Wave Super Grinder | 50:16 |
| 2014-10-27 | Storpey | 44,500 | Defense Grid 2 | Map 7 | Split Decision - I challenge you, Mack! | 57:07 |
| 2014-09-27 | Curly Hooligan | 717 | Defense Grid 2 Glitch - Shooting fish in a barrel | 1:50 |
| 2014-09-25 | Worth A Buy | 318,000 | Defense Grid 2 Review - Worth a Buy? | 10:30 |
| 2014-09-25 | Stuff+ | 127,000 | Preview + Defence Grid 2 | 26:36 |
| 2014-09-25 | GAME | 64,000 | Defense Grid 2 Launch Trailer | 1:03 |
| 2014-09-24 | outsidexbox | 2,680,000 | Defense Grid 2 Gameplay on Xbox One - Let's Play Defense Grid 2 | 8:37 |
| 2014-08-18 | Eurogamer | 753,000 | What is Defense Grid 2? - Preview - Eurogamer | 27:37 |
| 2013-04-28 | RedGamingTech | 109,000 | Defense Grid 2 News Sequel Funded on Kickstarter Thanks to Investor Gameplay Details & Release Date | 3:26 |
