| 1. |  Let's Play With Brigands | 314,074 | Maniac Mansion (Amiga Version | Full Playthrough) | 1:47:36 |
| 2. | wc10k | 245,702 | Let's Play Maniac Mansion (Nes) Part 11 Conclusion | 9:55 |
| 3. | PushingUpRoses | 198,031 | Let's Play: Maniac Mansion [part 10] with Roo (GOOD ENDING) | 17:30 |
| 4. |  NRWBoy18 | 190,959 | Lets Play - Indiana Jones und der letzte Kreuzzug [Teil 1] | 10:04 |
| 5. | MrVenom1974 | 152,213 | Wählt das nächste Re-Let's Play | Ihr entscheidet ^_^ | 11:05 |
| 6. | Greg's RPG HeaveN | 93,612 | LET'S PLAY Sam & Max Hit the Road // KOMPLETT 💿 LucasArts durchgeknalltes Grafik-Adventure (Deutsch) | 4:07:31 |
| 7. | Anachon | 52,576 | Let's Play Indiana Jones und der letzte Kreuzzug (Deutsch) #03 - Donovans Auftrag | 20:35 |
| 8. | DoctorM-LP | 19,347 | Lets Play MMM X-mas Odysee Teil 2 [ DoctorM Weihnachtsspecial ] [ HD ] | 23:14 |
| 9. | NintendoComplete | 14,750 | Maniac Mansion (NES) Playthrough | 3:10:36 |
| 10. | michael_stout79 | 10,465 | MANIAC MANSION Nintendo (NES) 1990 Game Play (EPISODE 1,072) Let's Play | 32:36 |
| 11. | VerticalSandwich | 9,229 | Let's Play Maniac Mansion (Wendy, Bernard) - The Finale! | 13:15 |
| 12. | Slowflake | 6,999 | Let's Play The Room - Part 6 | 13:42 |
| 13. |  The Mexican Runner | 5,054 | 45/714 Maniac Mansion (Part 2/2) - NESMania | 6:06:32 |
| 14. | DieWutbuerger | 4,338 | Let's Play Maniac Mansion #09 [Deutsch / German] together - Showdown mit dem Meteor - | 21:52 |
| 15. | Scribe | 4,227 | Let's Play Maniac Mansion (FINALE) - Night of the Tentacle | 32:23 |
| 16. | AringusOokami | 3,010 | Maniac Mansion Mania ♦ Staffel 2 ♦ Edgar Award Show II ♦ Let's Play | 35:38 |
| 17. | blutrotwurst | 2,730 | Lets Play Maniac Mansion[Deutsch]: #27 Endlich geschaft! | 18:38 |
| 18. | Kenshin1913 | 2,609 | Let's Play Maniac Mansion: Finale | 20:17 |
| 19. | LordSmapy | 2,177 | Let's Play Maniac Mansion, Part 10 - Wendy And Michael | 48:06 |
| 20. |  TurianShepard | 2,104 | DINOSAUR TAR PIT!! - Sam & Max Hit The Road (BLIND) #17 | 16:16 |
| 21. | ultralavos | 1,643 | Let's Play Maniac Mansion: 9 - Of Hamsters and Tentacles | 15:07 |
| 22. | Saintz | 1,205 | Let's Play Maniac Mansion [#07] Das epische Finale | 15:00 |
| 23. |  DarkEvil87's Longplays | 1,125 | Maniac Mansion - DarkEvil87's Longplays - Full Longplay (PC) | 0:00 |
| 24. | Gaming Jay | 937 | Maniac Mansion (DOS) - Let's Play 1001 Games - Episode 287 | 1:08:35 |
| 25. | Darth Vera (DarthVeraLP) | 785 | Let's Play Indiana Jones und der letzte Kreuzzug - #02 Veneeeeziaaaaaaaaaa!! | 13:42 |
| 26. | Sensei Starman | 724 | Sensei Starman Plays Meteor Mess - The Michael and Syd Playthrough | 1:36:11 |
| 27. | Lords of the Green Leaf | 698 | Let's Play: JA Back in Action [BLIND] Part 25: Visiting Miguel, Heading to San Mona, Maniac Mansion | 36:46 |
| 28. | Masters of Unlocking | 695 | Let's Play Maniac Mansion NES Part 11 - FINALE A End to all things Purple | 8:37 |
| 29. | Rafinoff | 519 | Maniac Mansion - Part 8 [Finale?] | Playthrough | 16:06 |
| 30. | ZetaPlays | 517 | Maniac Mansion (NES) - 02 - Summoning Space Police 27 Times | 33:18 |
| 31. | Ultra Publications | 508 | Let's Play: Maniac Mansion (NES) - Episode 4: One Possible Ending! | 20:18 |
| 32. | Wretch Plays | 407 | Let's Play Maniac Mansion - Part 2 | NES Wretch-rospective [Wretch Plays] | 36:05 |
| 33. | Marstead | 406 | ✔️️ Full Blind Playthrough (Maniac Mansion) | 4:01:25 |
| 34. | KIKI KLICKT - Let's Play point & click classic | 399 | BERLIN CONNECTION: Berliner Morgenpost Promo Spiel #4 ~ Gold Ede - Let's Play & Lösung [Deutsch] | 20:02 |
| 35. | TehloneGamer | 392 | Let's Play Maniac Mansion: Part 5 | 15:53 |
| 36. |  Spike Plays | 383 | Spike Plays #short Mira mamá sin manos - MANIAC MANSION | 0:12 |
| 37. | Rocket Baby Dolls LP | 363 | Let's Play: Maniac Mansion 01 | 15:45 |
| 38. | Famicom Dojo LIVE! | 308 | Planning a Heist - Sean Plays Maniac Mansion (NES), Part 4 | 1:32:34 |
| 39. | CarobiWing | 295 | Let's Play: Maniac Mansion #09 - Showdown in Dr. Freds Labor & alternatives Ende | 30:47 |
| 40. | Consequences | 281 | Maniac Mansion Mania Green Tentacle Needs Bernards Help Once Again! | 14:15 |
| 41. | VTuber Zeromaster & Power Plays | 253 | Maniac Mansion (NES) #PowerPlays FINALE?: Purple Donut Meteor | 12:13 |
| 42. |  Abandonware | 247 | Holiday games - C64 full playthrough | 11:47 |
| 43. |  Octotiggy | 245 | HAMSTER-FRIENDLY ZONE - Maniac Mansion (Amiga) - Livestream | 5:01:23 |
| 44. | Ennos RetrogameTV | 234 | Maniac Mansion:Rettet Sandy(Lets Play/C64)[Deutsch] | 21:40 |
| 45. | Gerste LP | 233 | Stellar Mess Demo Playthrough/Walkthrough [german/deutsch] | 52:14 |
| 46. | Corganto | 225 | Lets Play Maniac Mansion Mania - S01E02 - Unruhen 1.2 | 10:00 |
| 47. |  BitQuest | 224 | Maniac Mansion Finale | 17:39 |
| 48. | Video Games 101 | 223 | Maniac Mansion Playthrough | 4K 60FPS | Video Games 101 | 1:01:10 |
| 49. | Snarkfish T-Shirts | 221 | The Mistakes Were Made Dinocast - Episode 25: Maniac Mansion (Original) (Play Through) | 1:38:57 |
| 50. | KenneDeinePixel | 213 | 3BM ■ Let's Play Schreibers Quest | 38:54 |
| 51. | VertigoTeaparty | 208 | Let's Play Maniac Mansion (Steam version) - Full game | 2:52:46 |
| 52. | Torque | 205 | [GER/ENG] Let's Play "THE PIXEL HAS YOU" (DISK 1) from Daniele Spadoni | 16:13 |
| 53. | 10 Minute Gamer | 203 | 10MG Plays Maniac Mansion on NES | 10:33 |
| 54. | St. George's Games | 199 | Maniac Mansion: Chapter 2 - Don't Be A Tuna Head! | 0:00 |
| 55. | Mossi | 188 | Neo Magazin The Game Royale [HD] #3 [FINALE] - Zack feddich - Let's Play | 22:42 |
| 56. | Tolle Letsplays | 173 | Lets play Indiana Jones & the last crusade - 18 - Die 3 Prüfungen (deutsch) | 8:23 |
| 57. | REDDF1VE | 160 | Let's Play a BIT! #008 "Maniac Mansion" für PC (deutsch) HD | 1:06:29 |
| 58. |  Old Gidro | 158 | Gidrolo plays Maniac Mansion | 15:58 |
| 59. | Janno daddelt... | 154 | Let's Play The Cave (3/3) - Und wieder ist er planlos | 23:09 |
| 60. | Geeks and Nerds | 121 | Pablo Plays - Maniac Mansion US (Beta) (NES) | 14:54 |
| 61. | BirdieTheWise | 109 | Causing chaos driving around | 0:56 |
| 62. | Amigos Retro Gaming | 109 | Amigos Plays Maniac Mansion (Amiga) Full Playthrough | 2:20:47 |
| 63. |  Rob64 Gaming | 106 | Maniac Mansion - NES LetsPlay Deutsch | 9:02 |
| 64. | Self Indulgent Gamer | 105 | Creatures Demo, Commodore 64 playthrough | 10:26 |
| 65. | Vauldemare | 102 | Let's Play Sam & Max Hit the Road Part-11 Case Closed (Finale 2/2) | 29:34 |
| 66. | Retro Gaming Junction | 88 | Let's Play Maniac Mansion Fully | 1988 PC Enhanced Version | Horror Month | 2:23:49 |
| 67. | SUBPARCADE | 82 | Just a couple of tuna heads beating Maniac Mansion | 1:08:12 |
| 68. | RetroDetect | 82 | Maniac Mansion NES Full Playthrough (Dave Wendy Michael) | 45:50 |
| 69. | SGTBaker | 74 | "Let's not fail and not know it this time!" 1st playthrough of Maniac Mansion! Let's Play! (Part 2) | 3:32:57 |
| 70. |  Vampirschi Gaming | 72 | The Ritual - Playthrough (a short 2D point & click adventure) | 7:20 |
| 71. | sckchui | 70 | Blackwell series playthrough #5: Medium, Apparently | 21:25 |
| 72. | LULZCREW | 69 | Back To The Future IV: The Multitasking Crystal - PART 3 - Playthrough | 32:33 |
| 73. | Thomasretrogamer | 61 | " WELCOME TO THOMAS RETRO GAMER Plays Maniac Mansion (nes classic) " | 3:56:02 |
| 74. | th_pion | 60 | Let's Play: The Cave p22: Final | 16:39 |
| 75. | Ken Innes IV | 59 | Beating Maniac Mansion (NES) with Bernard & Wendy, My Playthrough (7/27/2023) | 1:21:42 |
| 76. | Bastisvlogs | 57 | Lets Play \\ Maniac Mansion Mania \\ Episode 30 \\ Memories of Zak | 21:09 |
| 77. |  Madhog Thy Master | 55 | MADPlay: "Sam & Max Hit The Road" [FULL PLAYTHROUGH] | 6:24:20 |
| 78. | Midstrighter | 54 | MANIAC MANSION 3/3 [ENDE] - Das überraschende Ende - Let's Play - [60FPS/Ger/HD] | 54:15 |
| 79. | TomBombaDeal | 52 | Him [01] Maniac Mansion alter! *LET'S PLAY* Deutsch/German | 20:54 |
| 80. |  Longplay Center | 52 | Maniac Mansion (NES) Playthrough [4K] | 1:04:29 |
| 81. | Funky G | 52 | Let's Play Maniac Mansion (BLIND) Part 5: FINALE | 1:01:05 |
| 82. | SuperBunnyBun | 49 | Maniac Mansion (NES) Lets-Play Episode 4 | 23:00 |
| 83. | TbMzockt | 48 | Indiana Jones 3 #007 — Und täglich grüßt das Schloss Brunwald [Let's Play] | 14:56 |
| 84. | RetroGameQuest | 46 | Quest #61: Maniac Mansion [NES] (Complete playthrough with Bernard) | 1:14:16 |
| 85. | SFO Arcade VODs | 39 | Let's Play MANIAC MANSION (For NES) -- No Talent Gaming HALLOWEEN | 2:10:10 |
| 86. | Binary Legends | 36 | Maniac Mansion Enhanced Play-through (Wendy - Contract) (Lucasfilm Games - 1989 - DREAMM) | 56:07 |
| 87. | FletchGTM | 36 | Loom (PC) - CAŁA GRA - PL (fanowskie tłumaczenie), bez komentarza | 1:43:11 |
| 88. | Video Game Attic | 33 | Maniac Mansion Playthrough (Wendy and Bernard) | 3:13:20 |
| 89. | Reliving Retro | 32 | I Can't Believe The Game Let's You Do THIS!! | Maniac Mansion Playthrough | 9:55 |
| 90. | Hawkzombie | 30 | HawkZombie Plays: The Melting Apartment | 21:09 |
| 91. | Wiihawk | 30 | Zak McKracken (C64) - Part 9 - Todesfalle Bermuda-Dreieck | Let's Play | 18:26 |
| 92. | PETEPLAYS | 25 | A lucrative publishing contract | PETEPLAYS Maniac mansion (Episode 5) | 24:23 |
| 93. | Ridiculoud | 22 | Let's Play Maniac Mansion - Technical Food - Part 2 - Ridiculoud | 10:18 |
| 94. | capn shrimpy | 21 | Super Death Defying Ending 15:06 Playthrough - Maniac Mansion (NES) | 17:27 |
| 95. | humaldo | 21 | MANIAC MANSION DELUXE • humaldo plays! Classics (2013) | 2:22:15 |
| 96. | Reppy2021 | 21 | Silver 023 - Let's Play - Maniac Mansion [German / Deutsch] | 31:47 |
| 97. | VGamingJunkieVT | 18 | 🎮 Let's Play 🎮 Maniac Mansion - The Hungry Tentacle? Get into That Mansion! | 32:15 |
| 98. | Mario Gamepro | 17 | Maniac Mansion Playthrough Part 9 I Give Up | 38:14 |
| 99. | Sir Nigel Cogs Gaming | 17 | Maniac Mansion #2 - Enter the Bernard | 27:45 |
| 100. | Proto Man | 16 | Let's Play Together | MANIAC MANSION #1 | 31:11 |
