| 1. |  Big Dan Gaming | Mass Effect Trilogy - ALL Squadmates & Crew Die in the WORST PLAYTHROUGH EVER (All 3 Games) | 1,358 | Let's Play |
| 2. | Cryaotic | Cry Plays: Always Sometimes Monsters [P6] | 798 | Let's Play |
| 3. | LucyusMaximus | My First Shepard!! | Mass Effect Legendary Edition Part 1 | First Playthrough | 643 | Let's Play |
| 4. | Angel Alyx | GOING IN BLIND! | Mass Effect Legendary Edition Let's Play Part 1 | 641 | Let's Play |
| 5. | DreamcastGuy | Amazon or Sony PlayStation might BUY EA GAMES?! Lets talk... | 484 | Let's Play |
| 6. | LiteWeight Gaming | Mass Effect Legendary Edition: Pt. 1 | IM IN LOVE | First Play Through - LiteWeight Gaming | 454 | Let's Play |
| 7. | BrainScratch Commentaries | Mass Effect - Part 1: A Shepard and Her Sheeple | 426 | Let's Play |
| 8. | LucyusMaximus | Meeting Wrex and Becoming a Spectre! | Mass Effect Legendary Edition Part 3 | First Playthrough | 388 | Let's Play |
| 9. | LucyusMaximus | The Search For Liara | Mass Effect Legendary Edition Part 4 | First Playthrough | 376 | Let's Play |
| 10. | Davey Gunface | The Mass Effect Trilogy playthrough so terrible, the genocidal space robots seem sensible | 352 | Let's Play |
| 11. | LiteWeight Gaming | Virmire | Mass Effect Legendary Edition: Pt. 25 | First Play Through - LiteWeight Gaming | 352 | Let's Play |
| 12. | LucyusMaximus | Ilos - The Final Showdown | Mass Effect Legendary Edition Part 20 | First Playthrough | 346 | Let's Play |
| 13. | LucyusMaximus | The Citadel ( + Garrus & Tali!) | Mass Effect Legendary Edition Part 2 | First Playthrough | 344 | Let's Play |
| 14. | Angel Alyx | THE CITADEL | Mass Effect Legendary Edition Let's Play Part 2 | 310 | Let's Play |
| 15. | LiteWeight Gaming | Sovereign | Mass Effect Legendary Edition: ENDING | First Play Through - LiteWeight Gaming | 305 | Let's Play |
| 16. | AwesomeMattG | Let's Play: Mass Effect 1 (001) "Creation of a Hero" | 260 | Let's Play |
| 17. | Caedo Genesis | 10+ TIPS & TRICKS I Wish I Knew (Basics/Advanced) - Mass Effect: Legendary Edition (ME1) | 252 | Let's Play |
| 18. | LiteWeight Gaming | Mass Effect Legendary Edition: Pt. 2 | GARRUS | First Play Through - LiteWeight Gaming | 251 | Let's Play |
| 19. | Angel Alyx | THE END | Mass Effect Legendary Edition Let's Play Part 14 | 248 | Let's Play |
| 20. | IGN | Marty Plays Mass Effect: Episode 1 - Saren Surprise Party | 233 | Let's Play |
| 21. | Big Dan Gaming | Can You Beat Mass Effect WITHOUT THE MAKO? (ME1 No Mako Playthrough) | 226 | Let's Play |
| 22. | LucyusMaximus | Virmire | Mass Effect Legendary Edition Part 18 | First Playthrough | 216 | Let's Play |
| 23. | LiteWeight Gaming | Confronting Wrex | Mass Effect Legendary Edition: Pt. 24 | First Play Through - LiteWeight Gaming | 209 | Let's Play |
| 24. | A Crab Named Heller | PlayStation Fanboys on SUICIDE WATCH After God of War Announced For PC! | 207 | Let's Play |
| 25. | IGN | Mass Effect Fans Engaged with a Little Help from Devs - IGN News | 199 | Let's Play |
| 26. | LiteWeight Gaming | Balak | Mass Effect Legendary Edition: Pt. 22 | First Play Through - LiteWeight Gaming | 196 | Let's Play |
| 27. | LucyusMaximus | Noveria Pt 2: Matriarch Benezia | Mass Effect Legendary Edition Part 13 | First Playthrough | 185 | Let's Play |
| 28. | Big Dan Gaming | JENKINS NOOOO!!! & Was I TOO MEAN to Ashley?? (Big Dan Plays Mass Effect Legendary Edition, Ep 1) | 182 | Let's Play |
| 29. | Angel Alyx | BECOMING A SPECTRE | Mass Effect Legendary Edition Let's Play Part 3 | 171 | Let's Play |
| 30. | Angel Alyx | KAIDAN OR ASHLEY!?! | Mass Effect Legendary Edition Let's Play Part 12 | 160 | Let's Play |
| 31. | LiteWeight Gaming | Mass Effect Legendary Edition: Pt. 4 | LIARA | First Play Through - LiteWeight Gaming | 160 | Let's Play |
| 32. | Keith Ballard | Let's Play Mass Effect Part 1 - Sigourney Shepard | 154 | Let's Play |
| 33. | Liera | ENDING! - Mass Effect Legendary Edition Pt.13 (Blind) | 151 | Let's Play |
| 34. | LiteWeight Gaming | Family Armor | Mass Effect Legendary Edition: Pt. 18 | First Play Through - LiteWeight Gaming | 151 | Let's Play |
| 35. | julia_tv | Mass Effect 1 First Playthrough! - Legendary Edition [Part 1] Becoming a Spectre | 150 | Let's Play |
| 36. | LiteWeight Gaming | Mass Effect Legendary Edition: Pt. 3 | SPECTER | First Play Through - LiteWeight Gaming | 150 | Let's Play |
| 37. | The RPG Chick | Let's Play Mass Effect (Blind), Part 1: Meet Commander Brittany Shepard | 149 | Let's Play |
| 38. | BrainScratch Commentaries | Mass Effect - Part 2: Resident Evil 2183 | 148 | Let's Play |
| 39. | Prince Vegeta | Vegeta Plays Mass Effect Legendary Edition | 145 | Let's Play |
| 40. | Angel Alyx | LIARA T'SONI | Mass Effect Legendary Edition Let's Play Part 7 | 143 | Let's Play |
| 41. | IGN | PlayStation Essentials Sale Offers Deep Discounts on P4G, Mass Effect Trilogy, and More - IGN News | 142 | Let's Play |
| 42. | Angel Alyx | FEROS | Mass Effect Legendary Edition Let's Play Part 4 | 135 | Let's Play |
| 43. | Angel Alyx | THORIAN | Mass Effect Legendary Edition Let's Play Part 5 | 135 | Let's Play |
| 44. | Liera | Oh, Virmire... - Mass Effect Legendary Edition Pt.12 (Blind) | 135 | Let's Play |
| 45. | LobosJr | Lobos Plays Mass Effect 1 (Part 1) | 132 | Let's Play |
| 46. | OriginalHuman | Mass Effect Legendary Edition | Sci-Fi Saturday (Royal Marine Plays) | 128 | Let's Play |
| 47. | LiteWeight Gaming | Mass Effect Legendary Edition: Pt. 6 | THE CITADEL | First Play Through - LiteWeight Gaming | 126 | Let's Play |
| 48. | LiteWeight Gaming | Mass Effect Legendary Edition: Pt. 5 | TEAM BUILDING | First Play Through - LiteWeight Gaming | 119 | Let's Play |
| 49. | Angel Alyx | CALM DOWN WREX! | Mass Effect Legendary Edition Let's Play Part 11 | 118 | Let's Play |
| 50. | JumpinProductions | Let's Play The Mass Effect Trilogy (Eden Prime) | 118 | Let's Play |
| 51. | The RPG Chick | Let's Play Mass Effect (Blind), Part 100: Revelations! [FINAL EPISODE] | 117 | Let's Play |
| 52. | LucyusMaximus | From Spectre to Space Pirate! | Mass Effect Legendary Edition Part 19 | First Playthrough | 116 | Let's Play |
| 53. | LiteWeight Gaming | The Thorian | Mass Effect Legendary Edition: Pt. 17 | First Play Through - LiteWeight Gaming | 115 | Let's Play |
| 54. | LucyusMaximus | Tali and the Geth | Mass Effect Legendary Edition Part 14 | First Playthrough | 115 | Let's Play |
| 55. | Angel Alyx | NOVERIA | Mass Effect Legendary Edition Let's Play Part 9 | 113 | Let's Play |
| 56. | LucyusMaximus | Maximum Paragon, Activate! | Mass Effect Legendary Edition Part 16 | First Playthrough | 112 | Let's Play |
| 57. | LiteWeight Gaming | Mass Effect Legendary Edition | Sha'ira | First Play Through - LiteWeight Gaming | 112 | Let's Play |
| 58. | AGirlAndAGame | Mass Effect WORST Playthrough Reaction π | 109 | Let's Play |
| 59. | LiteWeight Gaming | Space Monkeys!! | Mass Effect Legendary Edition: Pt. 23 | First Play Through - LiteWeight Gaming | 109 | Let's Play |
| 60. | BrainScratch Commentaries | Mass Effect - Part 3: Disarm and Destroy | 108 | Let's Play |
| 61. | Private Idaho | Eden Burning | Mass Effect Legendary Edition | FemShep Playthrough | ep.01 | 106 | Let's Play |
| 62. | BrainScratch Commentaries | Mass Effect - Part 9: Bringing Guns to a Fist Fight | 105 | Let's Play |
| 63. | BrainScratch Commentaries | Mass Effect - Part 28: 'Till Touch Down Brings Me Round Again | 104 | Let's Play |
| 64. | Private Idaho | Eden Prime and the Beacon | Mass Effect Legendary Edition | Blind Playthrough | (EP. 01) | 101 | Let's Play |
| 65. | LucyusMaximus | Batarians on Asteroid X-57! | Mass Effect Legendary Edition Part 15 | First Playthrough | 101 | Let's Play |
| 66. | IGN | Marty Plays Mass Effect Episode 10 - Shepard vs Saren | 100 | Let's Play |
| 67. | AwesomeMattG | Let's Play: Mass Effect 1 (054) "Final Battle + Credits" | 99 | Let's Play |
| 68. | BrainScratch Commentaries | Mass Effect - Part 6: An Actual Walk in the Park | 97 | Let's Play |
| 69. | Melonie Mac Gaming Streams | ππ Original Mass Effect Playthrough! Part 1ππ | 97 | Let's Play |
| 70. | AwesomeMattG | Let's Play: Mass Effect 1 (002) "First Taste of Action" | 96 | Let's Play |
| 71. | BrainScratch Commentaries | Mass Effect - Part 59: An End, Once and For Now | 96 | Let's Play |
| 72. | LucyusMaximus | Side Missions, Complete! | Mass Effect Legendary Edition Part 17 | First Playthrough | 94 | Let's Play |
| 73. | Angel Alyx | HELPING ZHU'S HOPE | Mass Effect Legendary Edition Let's Play Part 6 | 91 | Let's Play |
| 74. | BrainScratch Commentaries | Mass Effect - Part 7: Ward of My Heart | 91 | Let's Play |
| 75. | BrainScratch Commentaries | Mass Effect - Part 20: Welcome to the Plot Corridor! | 90 | Let's Play |
| 76. | BrainScratch Commentaries | Mass Effect - Part 15: The Batarians Strike Out | 89 | Let's Play |
| 77. | BrainScratch Commentaries | Mass Effect - Part 18: The Batarians Run Home | 88 | Let's Play |
| 78. | BrainScratch Commentaries | Mass Effect - Part 10: A Gift of... Words? | 87 | Let's Play |
| 79. | BrainScratch Commentaries | Mass Effect - Part 46: Geth, Would You Kindly GTFO | 86 | Let's Play |
| 80. | Angel Alyx | ON THE MOON!! | Mass Effect Legendary Edition Let's Play Part 8 | 86 | Let's Play |
| 81. | AwesomeMattG | Let's Play: Mass Effect 1 (013) "I Hate Biotic Krogans... no Offence Urdnot" | 83 | Let's Play |
| 82. | AwesomeMattG | Let's Play: Mass Effect 1 (012) "...But Baby Rhinos Are So Cute!" | 83 | Let's Play |
| 83. | BrainScratch Commentaries | Mass Effect - Part 25: Fly Me to the Moon | 82 | Let's Play |
| 84. | AwesomeMattG | Let's Play: Mass Effect 1 (004) "Let's Get Lost in the Citadel" | 81 | Let's Play |
| 85. | JumpinProductions | Let's Play The Mass Effect Trilogy FINAL PART | 81 | Let's Play |
| 86. | BrainScratch Commentaries | Mass Effect - Part 4: The Morning After | 81 | Let's Play |
| 87. | Bowskii | Commander On Deck! | Mass Effect 1 - Legendary Edition | Let's Play - Part 01 | 80 | Let's Play |
| 88. | IGN | Marty Plays Mass Effect Episode 11 - The Beginning of the End | 78 | Let's Play |
| 89. | MFPallytime | The End of Mass Effect 1 | Mass Effect Let's Play #23 | 78 | Let's Play |
| 90. | BrainScratch Commentaries | Mass Effect - Part 45: Attrition Gunner | 78 | Let's Play |
| 91. | BrainScratch Commentaries | Mass Effect - Part 22: Where's the Kaboom? There's the Kaboom. | 78 | Let's Play |
| 92. | BrainScratch Commentaries | Mass Effect - Part 26: In Other Words | 78 | Let's Play |
| 93. | BrainScratch Commentaries | Mass Effect - Part 29: Cerberus | 77 | Let's Play |
| 94. | Jesika Plays | Mass Effect | Legendary Edition | Let's Play | 50 | 77 | Let's Play |
| 95. | IGN | Marty Plays Mass Effect Episode 12 - The Final Episode | 76 | Let's Play |
| 96. | Angel Alyx | RACE AGAINST TIME | Mass Effect Legendary Edition Let's Play Part 13 | 75 | Let's Play |
| 97. | BrainScratch Commentaries | Mass Effect - Part 58: You're Driving Me Up the Wall | 74 | Let's Play |
| 98. | Dani Dutch | Renegade of Love | Ep 1 | Starting Mass Effect 1 | Blind First Playthrough | Legendary | Remastered | 74 | Let's Play |
| 99. | BrainScratch Commentaries | Mass Effect - Part 57: The Hyper-Advanced Alien Plot Dumpster | 74 | Let's Play |
| 100. | LiteWeight Gaming | Finding Dr. Saleon | Mass Effect Legendary Edition: Pt. 20 | First Play Through - LiteWeight Gaming | 74 | Let's Play |
