| 1. |  Cryaotic | Cry Plays: Always Sometimes Monsters [P6] | 257,346 | Let's Play |
| 2. | Big Dan Gaming | Mass Effect Trilogy - ALL Squadmates & Crew Die in the WORST PLAYTHROUGH EVER (All 3 Games) | 231,710 | Let's Play |
| 3. | Caedo Genesis | 10+ TIPS & TRICKS I Wish I Knew (Basics/Advanced) - Mass Effect: Legendary Edition (ME1) | 149,198 | Let's Play |
| 4. | Angel Alyx | GOING IN BLIND! | Mass Effect Legendary Edition Let's Play Part 1 | 147,822 | Let's Play |
| 5. | Washington Post Gaming | Playing Mass Effect Legendary with Shepard and Liara's voice actresses, Jennifer Hale and Ali Hillis | 104,198 | Let's Play |
| 6. | Davey Gunface | The Mass Effect Trilogy playthrough so terrible, the genocidal space robots seem sensible | 95,066 | Let's Play |
| 7. | LucyusMaximus | My First Shepard!! | Mass Effect Legendary Edition Part 1 | First Playthrough | 88,760 | Let's Play |
| 8. | HaydeeTheGame | Let's Play - Liara T'Soni as Haydee, Tutorial Speedrun (2m 03s) | 88,750 | Let's Play |
| 9. | Keith Ballard | Let's Play Mass Effect Part 1 - Sigourney Shepard | 82,093 | Let's Play |
| 10. | AwesomeMattG | Let's Play: Mass Effect 1 (001) "Creation of a Hero" | 71,619 | Let's Play |
| 11. | CohhCarnage | CohhCarnage Plays Mass Effect - Episode 1 | 65,177 | Let's Play |
| 12. | julia_tv | Mass Effect 1 First Playthrough! - Legendary Edition [Part 1] Becoming a Spectre | 64,363 | Let's Play |
| 13. | Angel Alyx | THE CITADEL | Mass Effect Legendary Edition Let's Play Part 2 | 54,481 | Let's Play |
| 14. | BrainScratch Commentaries | Mass Effect - Part 1: A Shepard and Her Sheeple | 47,602 | Let's Play |
| 15. | IGN | PlayStation Essentials Sale Offers Deep Discounts on P4G, Mass Effect Trilogy, and More - IGN News | 45,751 | Let's Play |
| 16. | HaydeeTheGame | Let's Play - Miranda Lawson as Haydee, Tutorial Speedrun (1m 53s) | 45,365 | Let's Play |
| 17. | FightinCowboy | Mass Effect Legendary Edition - Livestream Series Part 2 | 43,865 | Let's Play |
| 18. | IGN | Marty Plays Mass Effect: Episode 1 - Saren Surprise Party | 40,459 | Let's Play |
| 19. | Prince Vegeta | Vegeta Plays Mass Effect Legendary Edition | 38,987 | Let's Play |
| 20. | The RPG Chick | Let's Play Mass Effect (Blind), Part 1: Meet Commander Brittany Shepard | 33,764 | Let's Play |
| 21. | LucyusMaximus | The Citadel ( + Garrus & Tali!) | Mass Effect Legendary Edition Part 2 | First Playthrough | 33,047 | Let's Play |
| 22. | Hab Oh | My Favorite Liara Animation In The Game! // Mass Effect // #Shorts | 32,821 | Let's Play |
| 23. | AwesomeMattG | Let's Play: Mass Effect 1 (002) "First Taste of Action" | 31,428 | Let's Play |
| 24. | CohhCarnage | CohhCarnage Plays Mass Effect - Episode 2 | 31,388 | Let's Play |
| 25. | LiteWeight Gaming | Mass Effect Legendary Edition: Pt. 1 | IM IN LOVE | First Play Through - LiteWeight Gaming | 27,380 | Let's Play |
| 26. | Angel Alyx | BECOMING A SPECTRE | Mass Effect Legendary Edition Let's Play Part 3 | 27,250 | Let's Play |
| 27. | Big Dan Gaming | Can You Beat Mass Effect WITHOUT THE MAKO? (ME1 No Mako Playthrough) | 26,364 | Let's Play |
| 28. | Mal | Mass Effect [Modded] Let's Play Part 1 [W/ Side By Side Comparison Opening Scene] | 25,692 | Let's Play |
| 29. | Angel Alyx | THE END | Mass Effect Legendary Edition Let's Play Part 14 | 25,674 | Let's Play |
| 30. | Keith Ballard | Let's Play Mass Effect Part 2 - The Beacon | 23,436 | Let's Play |
| 31. | CohhCarnage | CohhCarnage Plays Mass Effect - Episode 3 | 23,271 | Let's Play |
| 32. | LobosJr | Lobos Plays Mass Effect 1 (Part 1) | 23,149 | Let's Play |
| 33. | AwesomeMattG | Let's Play: Mass Effect 1 (003) "I Think I Broke It..." | 23,132 | Let's Play |
| 34. | LucyusMaximus | Meeting Wrex and Becoming a Spectre! | Mass Effect Legendary Edition Part 3 | First Playthrough | 22,728 | Let's Play |
| 35. | IGN | Mass Effect Fans Engaged with a Little Help from Devs - IGN News | 22,617 | Let's Play |
| 36. | LucyusMaximus | The Search For Liara | Mass Effect Legendary Edition Part 4 | First Playthrough | 22,239 | Let's Play |
| 37. | IGN | Marty Plays Mass Effect Episode 11 - The Beginning of the End | 21,361 | Let's Play |
| 38. | Dani Dutch | Renegade of Love | Ep 1 | Starting Mass Effect 1 | Blind First Playthrough | Legendary | Remastered | 20,795 | Let's Play |
| 39. | IGN | Marty Plays Mass Effect: Episode 2 - Finding Fist | 20,605 | Let's Play |
| 40. | FightinCowboy | Mass Effect Legendary Edition - Livestream Series Part 7 | 20,421 | Let's Play |
| 41. | BrainScratch Commentaries | Mass Effect - Part 2: Resident Evil 2183 | 20,389 | Let's Play |
| 42. | Angel Alyx | FEROS | Mass Effect Legendary Edition Let's Play Part 4 | 20,202 | Let's Play |
| 43. | IGN | Marty Plays Mass Effect: Part 4 - Mako Makes Marty Crazy | 19,898 | Let's Play |
| 44. | CohhCarnage | CohhCarnage Plays Mass Effect - Episode 4 | 19,542 | Let's Play |
| 45. | Melonie Mac Gaming Streams | 🚀🚀 Original Mass Effect Playthrough! Part 1🚀🚀 | 19,111 | Let's Play |
| 46. | Private Idaho | Eden Prime and the Beacon | Mass Effect Legendary Edition | Blind Playthrough | (EP. 01) | 18,937 | Let's Play |
| 47. | BrainScratch Commentaries | Mass Effect - Part 3: Disarm and Destroy | 18,919 | Let's Play |
| 48. | julia_tv | Mass Effect 1 First Playthrough - Legendary Edition [Part 2] Noveria | 18,766 | Let's Play |
| 49. | Angel Alyx | KAIDAN OR ASHLEY!?! | Mass Effect Legendary Edition Let's Play Part 12 | 18,472 | Let's Play |
| 50. | Angel Alyx | THORIAN | Mass Effect Legendary Edition Let's Play Part 5 | 18,443 | Let's Play |
| 51. | AwesomeMattG | Let's Play: Mass Effect 1 (010) "Space Travel is Confusing" | 17,985 | Let's Play |
| 52. | Keith Ballard | Let's Play Mass Effect Part 3 - The Citadel | 17,769 | Let's Play |
| 53. | BrainScratch Commentaries | Mass Effect - Part 4: The Morning After | 17,627 | Let's Play |
| 54. | AwesomeMattG | Let's Play: Mass Effect 1 (004) "Let's Get Lost in the Citadel" | 17,513 | Let's Play |
| 55. | IGN | Marty Plays Mass Effect Episode 12 - The Final Episode | 17,433 | Let's Play |
| 56. | CohhCarnage | CohhCarnage Plays Mass Effect - Episode 5 | 17,134 | Let's Play |
| 57. | Ninja Flips | Mass Effect | Insanity Difficulty - Adept | Character Creation | PS3 Gameplay Part 1 | 17,117 | Let's Play |
| 58. | AwesomeMattG | Let's Play: Mass Effect 1 (005) "Please Do Not Disturb the Keepers" | 17,113 | Let's Play |
| 59. | DreamcastGuy | Amazon or Sony PlayStation might BUY EA GAMES?! Lets talk... | 17,091 | Let's Play |
| 60. | IGN | Marty Plays Mass Effect: Part 8 - Thrashing the Thorian | 17,077 | Let's Play |
| 61. | 🌸Tigerfrost🌸 | Let's Play Mass Effect (BLIND) - Episode 1 | 16,666 | Let's Play |
| 62. | IGN | Marty Plays Mass Effect: Part 3 - Get Wrex'd | 16,590 | Let's Play |
| 63. | Big Dan Gaming | JENKINS NOOOO!!! & Was I TOO MEAN to Ashley?? (Big Dan Plays Mass Effect Legendary Edition, Ep 1) | 16,315 | Let's Play |
| 64. | FightinCowboy | Mass Effect Legendary Edition - Livestream Series Part 8 | 16,046 | Let's Play |
| 65. | Angel Alyx | LIARA T'SONI | Mass Effect Legendary Edition Let's Play Part 7 | 15,941 | Let's Play |
| 66. | AwesomeMattG | Let's Play: Mass Effect 1 (011) "Ashley is Such a Liar" | 15,883 | Let's Play |
| 67. | BrainScratch Commentaries | Mass Effect - Part 6: An Actual Walk in the Park | 15,380 | Let's Play |
| 68. | CohhCarnage | CohhCarnage Plays Mass Effect - Episode 6 | 15,337 | Let's Play |
| 69. | julia_tv | Mass Effect 1 First Playthrough - Legendary Edition [Part 7] Virmire | 15,208 | Let's Play |
| 70. | Keith Ballard | Let's Play Mass Effect Part 4 - The Council | 15,197 | Let's Play |
| 71. | IGN | Marty Plays Mass Effect: Episode 5 - Benezia and the Rachni Queen | 15,131 | Let's Play |
| 72. | AwesomeMattG | Let's Play: Mass Effect 1 (006) "They Are Nothing Like Altair or Ezio" | 15,048 | Let's Play |
| 73. | BrainScratch Commentaries | Mass Effect - Part 7: Ward of My Heart | 14,866 | Let's Play |
| 74. | Angel Alyx | RACE AGAINST TIME | Mass Effect Legendary Edition Let's Play Part 13 | 14,752 | Let's Play |
| 75. | IGN | Marty Plays Mass Effect: Part 6 - Finding Liara On An Awful Planet | 14,498 | Let's Play |
| 76. | Angel Alyx | CALM DOWN WREX! | Mass Effect Legendary Edition Let's Play Part 11 | 14,475 | Let's Play |
| 77. | AwesomeMattG | Let's Play: Mass Effect 1 (008) "Finally, Fast Travel Stations" | 14,303 | Let's Play |
| 78. | LucyusMaximus | Ilos - The Final Showdown | Mass Effect Legendary Edition Part 20 | First Playthrough | 14,187 | Let's Play |
| 79. | Paula Deming | Mass Effect: Emotional Choices in Virmire | Paula Plays! (Blind Let's Play) | 14,172 | Let's Play |
| 80. | JumpinProductions | Let's Play The Mass Effect Trilogy (Eden Prime) | 14,116 | Let's Play |
| 81. | Keith Ballard | Let's Play Mass Effect Part 5 - Wrex & Tali | 13,987 | Let's Play |
| 82. | AwesomeMattG | Let's Play: Mass Effect 1 (007) "Tyranno-Garrus Wrex" | 13,895 | Let's Play |
| 83. | CohhCarnage | CohhCarnage Plays Mass Effect - Episode 7 | 13,755 | Let's Play |
| 84. | AGirlAndAGame | Mass Effect WORST Playthrough Reaction 😭 | 13,744 | Let's Play |
| 85. | pizzadudemanguy | Let's Play Mass Effect Trilogy (ME1), Part 1: Make It So | 13,690 | Let's Play |
| 86. | julia_tv | Mass Effect 1 First Playthrough - Legendary Edition [Part 3] Matriarch Benezia | 13,601 | Let's Play |
| 87. | Kinda Funny Games | Commander Nick Plays Mass Effect 1 | 13,542 | Let's Play |
| 88. | FightinCowboy | Mass Effect Legendary Edition - Livestream Series Part 9 | 13,458 | Let's Play |
| 89. | AwesomeMattG | Let's Play: Mass Effect 1 (009) "Spectre Shepard" | 13,073 | Let's Play |
| 90. | BrainScratch Commentaries | Mass Effect - Part 8: Good Cop, Bad Cop... Ugly Cop | 13,061 | Let's Play |
| 91. | pizzadudemanguy | Let's Play Mass Effect Trilogy (Playlist Cover) | 13,040 | Let's Play |
| 92. | CohhCarnage | CohhCarnage Plays Mass Effect - Episode 8 | 13,015 | Let's Play |
| 93. | Keith Ballard | Let's Play Mass Effect Part 7 - SSV Normandy SR-1 | 13,003 | Let's Play |
| 94. | Keith Ballard | Let's Play Mass Effect Part 6 - Garrus Vakarian | 12,979 | Let's Play |
| 95. | IGN | Marty Plays Mass Effect Episode 10 - Shepard vs Saren | 12,867 | Let's Play |
| 96. | LucyusMaximus | Virmire | Mass Effect Legendary Edition Part 18 | First Playthrough | 12,852 | Let's Play |
| 97. | BrainScratch Commentaries | Mass Effect - Part 9: Bringing Guns to a Fist Fight | 12,830 | Let's Play |
| 98. | BrainScratch Commentaries | Mass Effect - Part 10: A Gift of... Words? | 12,717 | Let's Play |
| 99. | IGN | Marty Plays Mass Effect: Part 7 - Can't Geth No Satisfaction | 12,550 | Let's Play |
| 100. | AwesomeMattG | Let's Play: Mass Effect 1 (054) "Final Battle + Credits" | 12,418 | Let's Play |
