| 1. |  Gencoil | 2,643,686 | Go For The Score [Mega Man 10 - "Fireball Strike" (Strike Man)] | 3:11 |
| 2. | WiiC24 | 1,607,457 | Mega Man 10 Music - Wily Capsule | 2:12 |
| 3. |  Rooster Teeth | 1,524,820 | Rage Quit - Mega Man 10 | Rooster Teeth | 4:14 |
| 4. |  ClementJ64 | 1,246,034 | Let's Play Mega Man 10! (Endless Attack/Challenges) | 8:14 |
| 5. | PrincessZelda2020 | 1,067,546 | Megaman 10 - Endless Maze(MM7 Remake) | 3:40 |
| 6. | StoneMonkWisdom | 1,063,796 | Happy 15th Anniversary | Mega Man 10 (NS) [Part 3] - Wily Castle, Weapons Archive, Wily Capsule | 0:00 |
| 7. | DeoxysPrime | 1,056,532 | Special Stage 2 (Get the Punk Out) - Mega Man 10 [OST] | 2:01 |
| 8. | RoahmMythril | 951,479 | Mega Man 10 - Punk Perfect Run | 9:41 |
| 9. | しゅーや | 941,296 | 【実況】ロボットも風邪を引く？ロックマン10をツッコミ実況part4 | 19:35 |
| 10. | darksydephil | 827,578 | Megaman 10 Kicks DSP's Ass pt25 (final) | 8:24 |
| 11. |  TheLegendofRenegade | 801,395 | Mega Man 10 - Solar Man Stage (MIDI Cover) | 1:30 |
| 12. | World of Longplays | 758,161 | Wii Longplay [079] Mega Man 10 (US) | 0:00 |
| 13. | EternalBlueSyaoran | 645,143 | Megaman 10 OST: Solar Inferno - Solar Man Theme | 2:55 |
| 14. | PinkKittyRose | 617,483 | Mega Man 10 (Bass Perfect Runs) - Blade Man's Stage | 7:40 |
| 15. |  SiIvaGunner | 515,110 | Nitro Rider (Nitro Man Stage) - Mega Man 10 | 0:00 |
| 16. | NintendoCapriSun | 492,464 | Let's Play Mega Man 10 Part 10: The End | 13:55 |
| 17. | AzureBlade49 | 481,688 | VGW: WiiWare - Mega Man 10 Special Stage 1 | 3:30 |
| 18. | Games Done Quick | 384,551 | Mega Man 10 by Slurpeeninja and Phil7 in 34:34 - Awesome Games Done Quick 2025 | 0:00 |
| 19. | Northernlion | 360,601 | Let's Play - Mega Man 10 - Episode 14 [Dr. Wily] | 19:52 |
| 20. | Rodriguezjr | 317,760 | Mega Man 10: Special Stage 3 (Ballade) | 4:04 |
| 21. |  Jogando A Saudade | 282,988 | Um pouco sobre BASS! | miniVIDEO | 1:46 |
| 22. | GaMetal | 281,480 | Solar Inferno [Solar Man Stage] (Mega Man 10) - GaMetal Remix | 4:01 |
| 23. | NintendoComplete | 265,976 | Mega Man 10 (Wii) Playthrough - NintendoComplete | 1:23:25 |
| 24. | TheMegaManNetwork | 264,265 | Comparing Mega Man 10's Endless Attack to Previous Mega Man Stages | 10:00 |
| 25. | BrainScratch Commentaries | 258,308 | Megaman 10 Part 7: Because Mega Buster.... that's why. | 17:15 |
| 26. | F4m1LyGuy10 | 229,314 | Full Mega Man 10 OST | 1:12:56 |
| 27. | SonikDude101 | 224,522 | Mega Man 10 - Part 6 [Wily Stages 3, and 4] | 10:20 |
| 28. | Maxim Zhuravlev | 213,555 | Mega Man 10 — Stage Select (Cover, Extended) | 15:54 |
| 29. | haconiwa | 208,658 | Mega Man 10 : Solar Man Remix | 2:46 |
| 30. | WebNations | 197,569 | TAS Mega Man 10 WII in 28:18 by diggidoyo | 34:10 |
| 31. | Overhazard | 197,312 | Mega Man 10 - Ending | 6:11 |
| 32. | MegaBong | 192,814 | Megaman (1-10) - All Wily Final Battles/Todos los final boss | 32:26 |
| 33. | JPhands | 180,687 | Megaman 10 Music Full OST Soundtrack Part 1 | 16:52 |
| 34. | TheEmero | 180,127 | Let's Play Mega Man 10 (Blind!) [Finale] - Spaaaace! | 14:19 |
| 35. | darkmurkrow | 165,183 | Wii Mega Man 10 "Bass, Hard Mode" TAS in 28:18.25 by diggidoyo | 34:01 |
| 36. | Seneloide | 161,160 | Rockman 10 IMAGE SOUNDTRACK - One and Only (LYRICS) | 3:33 |
| 37. |  Club Nientiendo | 155,768 | Mega Man 10 - Mega Reseña | 12:00 |
| 38. | SmashADP | 153,642 | Ending - Wily's Gift - Megaman 10 Music | 0:20 |
| 39. |  Diamg | 151,354 | El logro más difícil de Megaman 10 🤖🔥 | 0:53 |
| 40. | retsupurae | 148,320 | Let's Play Mega Man 10 before someone else does | 7:55 |
| 41. | Model CHP-3Y | 145,187 | Mega Man 10 Full OST Remixed | 1:08:45 |
| 42. | 社築 | 139,160 | 【ロックマン10 宇宙からの脅威!!】ハードなロックアクション、果たして10では如何に！？【にじさんじ/社築】 | 3:22:30 |
| 43. | TheBossHunters | 134,815 | Megaman 10 - Final Results | 0:45 |
| 44. |  Synthescissor | 132,568 | [10 Year Special] Mega Man 10: Wily Stage 1 (Arranged) | 11:13 |
| 45. | MegaQuint | 130,817 | Mega Man RAM - The Shepherd's Den Stage 1 | 5:45 |
| 46. |  Theofficialrevenge - Rev 2026 - | 130,510 | VEN A CONVERSAR UN RATITO! CLÁSICO DE LA VIDA SU MEGA MAN 10 | 2:44:34 |
| 47. | mega sfc | 128,487 | Mega Man 10 Commando Man Stage (Desert Commando)(MMX3 Soundfont) | 0:00 |
| 48. | Dracula9AntiChapel | 121,094 | Megaman 10 - Heart of Enker (Megaman X1 Arrange) | 3:08 |
| 49. | Refresh Gaming | 118,316 | Mega Man 10 (Pacifist): Part 16 - Special Stage 3 | 3:36 |
| 50. | tubeshark | 114,843 | Megaman 10 Wily themes | 10:03 |
| 51. | MegaPhilX | 114,689 | MegaMan 10 Review - PART 2/2 | 4:15 |
| 52. | BikdipOnABus | 114,055 | Twitch Stream: Mega Man 10 | 3:13:36 |
| 53. | Rheylis | 113,695 | Mega Man 10 (Xbox 360) | 3:45:45 |
| 54. |  テラゾーゲームス | 112,917 | 卍【鬼畜HARDロックマン10】ザコ不殺ブルースプレイ【実況】 09 | 27:05 |
| 55. | TASVideosChannel | 111,017 | [TAS] Wii Mega Man 10 "Mega Man" by diggidoyo in 33:42.37 | 0:00 |
| 56. | してよろ | 109,763 | ロックマン10(MegaMan10) Part 13 | 14:59 |
| 57. | Mike Essa | 108,778 | Megaman 10 - Special Stage 3 (Ballad of the Ballade) | 4:11 |
| 58. | Shadowserg | 108,722 | Mega Man 10 (Wii) All Bosses (No Damage) | 23:49 |
| 59. | zuschzero | 107,243 | Mega Man 10 - Thunder Wool Only Walkthrough | 50:57 |
| 60. |  RehicolReplay | 106,609 | Megaman 10 (Wii) - Debilidades de Todos los Jefes Mr. Perfect (Difícil, Sin Daño) RehicolReplay | 0:00 |
| 61. | MetalSmasherGaming | 105,075 | Mega Man 10 Hard Mode - Finale | 19:08 |
| 62. | Robin | 100,005 | Mega Man 8-Bit Deathmatch Shenanigans 2 (ZOMBIES IN THE POOL) | 12:49 |
| 63. | Bmeister42 | 98,728 | Megaman 10 Speedrun - 00:28:29 - Part 6 | 8:08 |
| 64. |  MET | 93,146 | Get the Punk Out - MM10GP (extended) | 15:03 |
| 65. | Suishomaru | 90,757 | Let's Play Megaman 10 [Hard Mode / German] - #8.2 - Ersehntes Ende, ah! | 11:36 |
| 66. | ふぅみん | 89,393 | やり直し可でいくロックマン1 つまり 壁抜け （令和7年）2025年12月7日 | 0:00 |
| 67. | Jaymonius | 88,677 | Megaman 10 (Bass Mode) - Supposed to have been Part 12 | 9:28 |
| 68. | Canal Dahora | 88,230 | O que houve entre Megaman Clássico e Megaman X? | 18:46 |
| 69. | 40Nix | 83,594 | (REUPLOAD) [Mega Man 10] BLADE MAN STAGE (MM&B style remix) | 0:00 |
| 70. | Can't Afford To Not | 82,668 | Mega Man 10 Dr. Wily Stage 5 CASTLE WALKTHROUGH COMPLETE MEGAMAN | 2:25 |
| 71. |  Megaman X-001 | 77,984 | Shooting Star (feat. anporin) - ROCKMAN HOLIC Soundtrack Sub Español | 4:23 |
| 72. | LuizPrower | 76,186 | Megaman 10 | 2:36:55 |
| 73. | Enderlessness | 75,662 | Top 10 Mega Man 10 Songs | Fun Ranking #megaman #megaman10 #ost | 0:00 |
| 74. | teckworks | 75,158 | Mega Man 10 - Polluted Pump [teckworks cover] | 2:02 |
| 75. | Nintendo Force Magazine | 74,569 | Mega Man 10 OST – Commando Man Stage Theme | 4:39 |
| 76. | まるピンクのアクションゲーム解説レビュー | 74,401 | 【解説】ロックマン10宇宙からの脅威!!レビュー【2Dアクション】【Wii】【レトロゲーム】【PS3】 | 23:58 |
| 77. | SomeRetroMan1998 | 69,870 | Mega Man - Ice Man (Mega Man 10 Wii-Style) | 0:00 |
| 78. | swordlunge | 68,682 | Detonado de Mega Man 10 #5 (FINALE) - "Mundo Invertido" | 25:07 |
| 79. | きらり☆ももんが | 68,544 | 【ロックマン10 宇宙からの脅威！！】ワイリーステージから！ クリアまでいきたい！！ 【癒しボイスでおやすみ配信】 | 0:00 |
| 80. | RayofLightning | 68,273 | Megaman 10 Special Stage 3 | 2:57 |
| 81. | RRThiel | 67,704 | FCP3: Mega Man 10 - Challenge Mode [VRC6] | 2:08 |
| 82. | Claris | 64,101 | Mega Man 10 - Hard Boss Challenges (part 2) | 10:23 |
| 83. | metalN22 | 63,036 | MegaMan 9 , MegaMan 10 pc [Link de descarga] | 8:40 |
| 84. |  Croby | 61,738 | How to make MegaMan 10 near perfection! | 0:00 |
| 85. | DJ Good Natured Gutter Godsmack | 61,329 | Mega Man Legacy Collection 2 - How To Unlock Bass & Protoman | 2:32 |
| 86. | CGRundertow | 60,244 | CGRundertow MEGA MAN 10 for Nintendo Wii Video Game Review | 4:10 |
| 87. |  Melodic Guitar Rock/Metal GuiltyGearRockYou | 58,955 | [Mega Man] Rockman 10 Instrumental Rock Track - "Against The Pressure" | 3:05 |
| 88. | 8BitDanooct1 | 58,691 | Famitracker - Megaman 10 - Wily Capsule | 1:24 |
| 89. | インサイド＆Game*Spark動画チャンネル | 58,510 | ロックマン10 宇宙からの脅威!! ダイナミックカスタムテーマ3 | 1:28 |
| 90. | wtks | 57,282 | ロックマン10 宇宙からの脅威！！ ブルース13 EASY ワイリーステージ5-END | 8:49 |
| 91. | TheNintendoCode | 56,775 | Mega Man 10 - Commando Man "Desert Commando" (Jazz Remix) | 2:53 |
| 92. | bdcool213 | 54,302 | Mega Man 10 - Wily Castle 5 of 5 & Ending | 10:09 |
| 93. | OverClocked ReMix: Video Game Music Community | 53,419 | Mega Man 10 ReMix by Magellanic: "Chivalrous Medicinal Murder" [Dr. Wily Stage 1] (#3486) | 3:35 |
| 94. | Armored-Struggle-Wagon | 53,242 | Mega Man 10 - Solar Man (Wily Wars Style) | 0:00 |
| 95. | VixyNyan (ヴィクシ) | 52,411 | Rockman 10: Threat from Outer Space!! (X360) Game Clear! (HD60) | 1:10:03 |
| 96. |  BaghiraZero | 52,341 | Wily Stage 3 (Devilish Elevators Remix) - Mega Man 10 / Rockman 10 | 0:00 |
| 97. | cjszero01 | 51,855 | Reviewed: Megaman 10 | 5:36 |
| 98. | kNIGHTWING01 | 50,570 | Mega Man 10 (Wii) Review part 2 | 3:56 |
| 99. | JJTam | 50,295 | Megaman 10 - Strike Man "Fireball Strike" Remix | 1:59 |
| 100. | Alouette EXE | 49,420 | Megaman 10 - Chill Man (Absolute Chill) - MM8 Style V2 (Revised) | 4:25 |
