| 1. |  DylanteroLive | ASÍ SI CTM -TBOIA+ -Ep 4 | 240 | |
| 2. | Pixelados | COMO DIBUJAR A ISAAC DE THE BINDING OF ISAAC EN PIXEL ART - PIXELADOS | 39 | |
| 3. | LowDefinitionLD | Obsesión The Binding of Isaac | 28 | |
| 4. | Alejandro Cordero | The Binding of Isaac - Panchito me enseña a jugar | 22 | |
| 5. | PabloZX | Applecore pero un amigo y yo lo cantamos (but me and a friend sing it) | 15 | |
| 6. | Mr Smile | CUANTO CARIÑO HAY EN ESTE RAP | THE BINDING OF ISAAC (MACRO-RAP) | Mr Smile | 14 | |
| 7. | Ju3qu8n | The binding of isaac aftherbirth plus - tercera partida parte 2 | 11 | |
| 8. | Temis | LA LISTA DE EMINEM | Temis | 10 | |
| 9. | luuiii1 | Salio justito #thebindingofisaac #vtuber #shorts | 8 | |
| 10. | Gorgonita Gaming | Gracias, no estoy loco #clipstwitch #shorts #twitchchile #gorgonita #thebindingofisaac | 6 | |
| 11. | SOLOenVIVO | #Isaac en 1 minuto #4 #shorts | 5 | |
| 12. | oliver6hallo | the binding of Isaac op items part 2 | 5 | |
| 13. | Don Indies | "Ésta será mi mejor obra" - Creador del The binding of Isaac | 5 | |
| 14. | cronigal gaming | ⚔️ ¿TE ANIMAS a ENTRAR a estos 14 ADICTIVOS MUNDOS en 2D?⚔️ | 5 | |
| 15. | ElRetorMasCSM | The Binding Of Isaac #2 I devuelta al nivel 1 F :( | 5 | |
| 16. | abysac | ¡ Puede ser que ahora si se logro ! (The Binding Of Isaac: Repertance) | 4 | |
| 17. | ElRetorMasCSM | Completando The Binding Of Isaac (depues de 3 intentos XDD) | 4 | |
| 18. | Maycol Gamer 026 | MG026 MUGEN - Deadpool #19 vs. Isaac (OHMSBY) | 4 | |
| 19. | Palteitor | The Binding of Isaac Wrath of the Lamb (La Viuda) | 3 | |
| 20. | T427 | easy win #Shorts | 3 | |
| 21. | KrakerPaladio | Volvemos a jugar a este Juegazo - The binding of isaac Repetence (#4) | 3 | |
| 22. | Raccer | the binding of isaac drawing timelapse | 3 | |
| 23. | ElStickman | The Binding Of Isaac | MAMA PORQUE! | Parte 1# | #StickProGames en español | 3 | |
| 24. | Black_Stark2 | A Dark Fantasy Bosh Rush RPG | Fowl Scourge Demo | 2 | |
| 25. | abysac | Increible run con Blue Baby Gran enfrentamiento al final ( The Binding Of Isaac: Repertance) | 2 | |
| 26. | matriXx XD | Un mono es mas inteligente que yo XD Binding of Isaac | 2 | |
| 27. | Excorpion | Porque Mato Inocentes ?!? - The Binding of Isaac #0 | 2 | |
| 28. | IXIDoctorIXI | No valgo nada aquí XD - Run diaria2 - The Binding of Isaac | 2 | |
| 29. | RBTTIM | A normal run in The Binding of Isaac Repentace | 2 | |
| 30. | SCPSP | Desbloqueando mas cosas - The Binding Of Isaac Afterbirht+ | 2 | |
| 31. | IXIDoctorIXI | Un juego normal... creo XD - The binding of Isaac | 2 | |
| 32. | Ju3qu8n | The binding of Isaac aftherbirth plus - sotano | 2 | |
| 33. | Palteitor | The Binding of Isaac: Wrath of the Lamb (Gurdy) | 2 | |
| 34. | martox thekiller | Hablando Sobre Los Furrys Mientras Juego The Binding Of Isaac Repentence | 2 | |
| 35. | NimyFair | DEAD GOD!!! 100% DE REPENTANCE PARTIDAZA CON THE LOST!! / THE BINDING OF ISAAC AL 1001% Y MAS | 1 | |
| 36. | SOLOenVIVO | La sinergia belica. | 1 | |
| 37. | LUCHO | The binding of isaac - isaac #1 | 1 | |
| 38. | abysac | Buena partida, pero a que precio (The Binding Of Isaac: Repertance) | 1 | |
| 39. | IXIDoctorIXI | Run madrugadora - Run diaria 1 - The Binding of Isaac | 1 | |
| 40. | KrakerPaladio | Jugando a The binding of isaac (Espero que youtube no me lo elimine :p) | 1 | |
| 41. | LUCHO | The binding of isaac - todos los finales | 1 | |
| 42. | Mapaxxxe | Directo | The Binding Of Isaac | NUEVO DLC | #2 | 1 | |
| 43. | Palteitor | The Binding of Isaac Wrath of the Lamb (Gurdy Jr) | 1 | |
| 44. | KrakerPaladio | Jugando con alt samson - The Binding of Isaac Repetence (#3) | 1 | |
| 45. | ALLAN Demoncryst | Voy a por The Lamb |The Binding of Isaac parte 1 | 1 | |
| 46. | HeySeken | El Inicio de Isaac / The Binding of Isaac Aferbirth | 1 | |
| 47. | IXIDoctorIXI | Cansansio del doctor - The binding of Isaac | 1 | |
| 48. | ElStickman | StickProGames vs Mama! | The Binding Of Isaac | Parte 2# | #StickProGames en español | 1 | |
| 49. | IXIDoctorIXI | La run mas corta de la vida - Run diaria 4 - The binding of Isaac | 1 | |
| 50. | T427 | The most annoying enemy in Isaac... it tooks 22 seconds to be defeated. #Shorts | 1 | |
| 51. | ~ [ The Benyie Lets Play ] ~ | Hola Pequeño amigo :3 / The Binding of isaac | 1 | |
| 52. | Ju3qu8n | The binding of isaac aftherbirth plus - batalla contra mama | 1 | |
| 53. | RebelDYTR | the binding of isaac repentence comtinuacion del episodio 2 | 1 | |
| 54. | RebelDYTR | the binding of isaac repentence completando challenges | 1 | |
| 55. | Palteitor | The Binding of Isaac Wrath of the Lamb (Larry Jr) | 1 | |
