| 1. |  LetsPlay | Is the Key to Life College Loans? - The Game of Life 2 w/ Kayla | 280 | Let's Play |
| 2. |  PeenoisePlays | PEENOISE PLAY THE GAME OF LIFE #01 - Fate Decided! | 163 | Let's Play |
| 3. |  Dhalucard | KOHLE MACHEN und SCHLECHT WÜRFELN 🎲 - ♠ The Game of Life 2 #001 ♠ | 88 | Let's Play |
| 4. | KwingsLetsPlays | Ultimate Selects!!! The Game of LIFE 2! (Nintendo SWitch) | 77 | Let's Play |
| 5. | lonniedos | IT'S A BOY! DOYLE JR. // The Game of Life #2 (iOS) | 56 | Let's Play |
| 6. | Stumpt | Game of Life 2 - Superhero World DLC! (4-Player Gameplay) | 46 | Let's Play |
| 7. | Stumpt | GET A SNAIL FARM! - Game of Life 2 (4-Player Gameplay) | 45 | Let's Play |
| 8. | Stumpt | Cassette Tapes are AWFUL - Game of Life 2 (4-Player Gameplay) | 36 | Let's Play |
| 9. | Stumpt | COLLEGE IS FOR SUCKERS! - Game of Life 2 (4-Player Gameplay) | 35 | Let's Play |
| 10. | Verzichten | [FULL ROUND] The Amigops (Sykkuno, Rae, Corpse, and Toast) Plays The Game of Life 2 | Toast in Debt! | 30 | Let's Play |
| 11. | Stumpt | SCALPERS: Turtle & the Moonshine Gang (4 Player Gameplay)[Twitch Highlight] | 29 | Let's Play |
| 12. | Stumpt | LASER TAG IS STILL AROUND?! - Game of Life 2 (4-Player Gameplay) | 26 | Let's Play |
| 13. |  FiloPixie | MY FRIENDS ARE DEAD | PixiePlays | The Hunger Games Simulator (YouTuber's Edition) | 24 | Let's Play |
| 14. | Stumpt | POWER UP YOUR PUTTING SKILLS! - Putt Party (4 player gameplay) | 13 | Let's Play |
| 15. | FatLP | Das Spiel des Lebens 2 -deutsch- 001 - Wie Erfolgreich meistere ich mein Leben? | 12 | Let's Play |
| 16. | Spielemagazin | Das Spiel des Lebens 2 Switch | Lets Play Game of Life 2 Deutsch Switch | Spiel des Lebens 2 Deutsch | 8 | Let's Play |
| 17. | Spielemagazin | Lets Play Das Spiel des Lebens 2 Switch Multiplayer / Online-Mehrspieler Gameplay Deutsch | 6 | Let's Play |
| 18. |  Hasanabi Gaming VODs | Hasanabi Plays The Game of Life 2 with xQc, Adept and Zoil [12/16/20] | 5 | Let's Play |
| 19. | ShinyRcGamer | ANDREW TATE PLAYS THE GAME OF LIFE WITH THE BOYS (Game of Life 2) | 5 | Let's Play |
| 20. | 2SI | These are some NICE PALS | The Game of Life 2 Ft @jikeandhank | 4 | Let's Play |
| 21. | Hopplhase | The Game of Life 2 - Es ist Zeit, das Nest zu verlassen! | 4 | Let's Play |
| 22. | Lirik Plays | Lirik plays THE GAME OF LIFE 2 | 4 | Let's Play |
| 23. |  Kozma Games | Competimos no Jogo da Vida! THE GAME OF LIFE 2 (Gameplay em Português PT-BR) | 4 | Let's Play |
| 24. | CouchCapades | Life Takes No Jons | The Game of Life 2 | 4 | Let's Play |
| 25. | CouchCapades | I AM THE PIGGY QUEEN | The Game of Life 2 | 2 | Let's Play |
| 26. | OTV Clips | Valkyrae plays The Game of Life with friends | 2 | Let's Play |
| 27. | Hopplhase | The Game of Life 2 - Das Leben geht weiter! | 2 | Let's Play |
| 28. | NanashiGaming96 | Let's Play - The Game of Life 2 | Pure Imagination - Part 2 (DLC) | 2 | Let's Play |
| 29. | Nintendo Dads | The Game of Life 2 - Let's Play | Nintendo Switch | 1 | Let's Play |
