Achlorhydria
0Achlorhydria, by Wikipedia https://en.wikipedia.org/wiki?curid=1002721 / CC BY SA 3.0
#Stomach_disorders
Achlorhydria and hypochlorhydria refer to states where the production of hydrochloric acid in gastric secretions of the stomach and other digestive organs is absent or low, respectively.
It is associated with various other medical problems.
Irrespective of the cause, achlorhydria can result as known complications of bacterial overgrowth and intestinal metaplasia and symptoms are often consistent with those diseases: Since acidic pH facilitates the absorption of iron,
achlorhydric patients often develop iron deficiency anemia.
Acidic environment of stomach helps conversion of pepsinogen into pepsin, which is highly important in digesting the protein into smaller components,
such as a complex protein into simple peptides and amino acids inside the stomach, which are later absorbed by the gastrointestinal tract.
Bacterial overgrowth and B12 deficiency （pernicious anemia） can cause micronutrient deficiencies that result in various clinical neurological manifestations,
including visual changes, paresthesias, ataxia, limb weakness, gait disturbance, memory defects, hallucinations and personality and mood changes.
Risk of particular infections, such as Vibrio vulnificus （commonly from seafood） is increased.
Even without bacterial overgrowth, low stomach acid （high pH） can lead to nutritional deficiencies through decreased absorption of basic electrolytes （magnesium, zinc, etc.） and vitamins （including vitamin C, vitamin K, and the B complex of vitamins）.
Such deficiencies may be involved in the development of a wide range of pathologies, from fairly benign neuromuscular issues to life-threatening diseases.
Age It was found that the incidence of achlorhydria in patients under the age of 60 was around 2.
3%, whereas it was 5% in patients over the age of 60.
In a person's 30s, the prevalence is about 2.
5%, and increases to 12% in a person's 80s.
An absence of hydrochlori...
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