| 301. | I Asked Angels For Better Items And This Happened! Free Win For Tainted Jacob! | 25 | | The Binding of Isaac: Rebirth
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| 302. | How Much Damage Can I Get? Tainted Azazel's Richest Run In The World! | 25 | | The Binding of Isaac: Rebirth
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| 303. | Best Deal In The Game? Rigging With Tainted Judas! | 24 | | The Binding of Isaac: Rebirth
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| 304. | Luck Gives Damage! Powerful Tainted Lost Run! | 24 | | The Binding of Isaac: Rebirth
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| 305. | Sacred Heart Start!? Can I Afford It? | 24 | | The Binding of Isaac: Rebirth
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| 306. | How To Break The Game? The Luckiest Maggy Run! | 24 | Guide | The Binding of Isaac: Rebirth
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| 307. | Regular Tainted Keeper Run! (Actually Not) | 24 | | The Binding of Isaac: Rebirth
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| 308. | The Wisp Master! Forgotten Double Book Run! | 23 | | The Binding of Isaac: Rebirth
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| 309. | The Most Powerful Melee Synergy In Repentance!? Insane Isaac Run! | 23 | | The Binding of Isaac: Rebirth
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| 310. | This Why You Should Always Gamble! Lucky Rerolls With Lost! | 23 | | The Binding of Isaac: Rebirth
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| 311. | Void Or Abyss? First Run In New Repentance Patch! | 23 | | The Binding of Isaac: Rebirth
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| 312. | The Most Popular Synergy In Repentance! Brimstone + C Section! | 23 | | The Binding of Isaac: Rebirth
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| 313. | Rainbow Technology! Eden Crazy Disco Run! | 23 | Vlog | The Binding of Isaac: Rebirth
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| 314. | This Trinket Literally Cursed Me! The Best Devil Items In Repentance! (actually not) | 22 | | The Binding of Isaac: Rebirth
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| 315. | I Got 3 Planetarium Items In One Run! The Cutest Eden Ever! | 22 | | The Binding of Isaac: Rebirth
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| 316. | One Million Tears! Infinite Items With Magic Skin! | 22 | | The Binding of Isaac: Rebirth
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| 317. | Eden And 10x Eden's Blessing! Powerful Item Boost? | 22 | | The Binding of Isaac: Rebirth
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| 318. | I Got The Perfect Brimstone Synergy! Luckiest Judas' Run! | 22 | | The Binding of Isaac: Rebirth
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| 319. | Triple Homing Rainbow Brimstone! Flipping with Eden! | 22 | | Brimstone
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| 320. | Fiend Folio - RIGGED! The Most Epic Mega Satan Fight! | 22 | | The Binding of Isaac: Rebirth
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| 321. | I Did It Again! Tainted Judas' Double Death Certificate Run! | 22 | | The Binding of Isaac: Rebirth
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| 322. | D20 Game Break, But It's Not Greed Mode! | 21 | | The Binding of Isaac: Rebirth
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| 323. | Lamb Speedrun, But I Have Only 1 Item! | 21 | | The Binding of Isaac: Rebirth
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| 324. | I Turned Regular Eden Into Tainted One! Is It Even Possible? | 21 | | The Binding of Isaac: Rebirth
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| 325. | Best Item In The Game? Lost's Insane Game Break! | 21 | | The Binding of Isaac: Rebirth
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| 326. | CAN I 1 SHOT DELIRIUM??? | 21 | | The Binding of Isaac: Rebirth
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| 327. | C Section + Godhead + Almond Milk! Amazing Synergy In Repentance! | 21 | | The Binding of Isaac: Rebirth
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| 328. | My first game break in Repentance! Eden overpowered run! | 21 | | The Binding of Isaac: Rebirth
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| 329. | I Wanted To Restart This!? Tainted Jacob Melts Bosses! | 20 | | The Binding of Isaac: Rebirth
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| 330. | How the real guys unlock The Forgotten! Crazy Azazel run! | 20 | | The Binding of Isaac: Rebirth
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| 331. | The King Of Red Rooms! Can I Open Them All? | 20 | | The Binding of Isaac: Rebirth
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| 332. | 300 DMG??? Tainted Keeper's Explosive Run! | 20 | | The Binding of Isaac: Rebirth
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| 333. | How To Melt Enemies Guide! Tainted Eve's Holy Run! | 20 | Guide | The Binding of Isaac: Rebirth
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| 334. | The most ultimate crazy run that no one can win (+Dead God) | 20 | | The Binding of Isaac: Rebirth
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| 335. | Am I Lucky Enough?! Risky Judas' Run! | 20 | | The Binding of Isaac: Rebirth
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| 336. | Brimstone is getting out of control!!! Tainted Lost to Mother #1 | 20 | | The Binding of Isaac: Rebirth
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| 337. | Fists And Flames! Lazarus Run With Perfection! | 19 | | The Binding of Isaac: Rebirth
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| 338. | Path Of The Jedi! Tainted Keeper Greedier! | 19 | | The Binding of Isaac: Rebirth
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| 339. | Don't Try This At Home! Eden's Risky Rainbow Run! | 19 | | The Binding of Isaac: Rebirth
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| 340. | Don't eat cookies with milk! Tainted Keeper rainbow run! | 18 | | The Binding of Isaac: Rebirth
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| 341. | Incredible DMG boost! Tainted Lost to Mother #2 | 18 | | The Binding of Isaac: Rebirth
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| 342. | The hardest choice in my life! Tainted Lost to Mother #8 | 18 | | The Binding of Isaac: Rebirth
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| 343. | How Can I Survive? Tainted Jacob Birthright! | 18 | | The Binding of Isaac: Rebirth
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| 344. | Shooting skittles! Eden to Delirium | 18 | | The Binding of Isaac: Rebirth
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| 345. | This Is Too Random For Me... Eden Reroll Madness! | 18 | | The Binding of Isaac: Rebirth
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| 346. | 100 LUCK RUN!!! Tainted Lost to Mother #9 | 17 | | The Binding of Isaac: Rebirth
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| 347. | Fetus Mega Splash! Eden Got The Luck! | 17 | | The Binding of Isaac: Rebirth
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| 348. | This Genesis Was Just Perfect! Tainted Lost To Mother! | 17 | | The Binding of Isaac: Rebirth
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| 349. | This Item Gives Infinite Damage! My Craziest Tainted Eve Run! | 17 | | The Binding of Isaac: Rebirth
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| 350. | Damocles Mongo Gang! Tainted Lost to Mother #4 | 17 | | The Binding of Isaac: Rebirth
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| 351. | Luckiest Chaos So Far!? | 17 | | The Binding of Isaac: Rebirth
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| 352. | This run just gone wrong... Apollyon to... | 17 | | The Binding of Isaac: Rebirth
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| 353. | ONE ITEM WIN - LEMEGETON! Tainted Lost to Mother #7 | 16 | | The Binding of Isaac: Rebirth
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| 354. | ONE MILLION BRIMSTONES!!! Isaac To Delirium X3 | 16 | | The Binding of Isaac: Rebirth
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| 355. | 20X Brimstone Ring Shot! Satisfying Tainted Isaac Run! | 16 | | The Binding of Isaac: Rebirth
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| 356. | I Got Huge Lasers! Tainted Lost's Electric Run! | 15 | | The Binding of Isaac: Rebirth
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| 357. | This run is deliriously good! Cain to Delirium | 15 | | The Binding of Isaac: Rebirth
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| 358. | I'll never get this lucky again! Tainted keeper free win start (gone wrong) | 15 | | The Binding of Isaac: Rebirth
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| 359. | 1000 FETUSES PER SECOND! Insane Meme Run! (Gone wrong) | 15 | | The Binding of Isaac: Rebirth
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| 360. | Tainted Lost to Beast: ELECTRO RAVE | 15 | | The Binding of Isaac: Rebirth
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| 361. | SPRAY DOWN THE BOSS!!! | 14 | | The Binding of Isaac: Rebirth
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| 362. | The Perfect Ending! Tainted Lost to Mother #10 | 14 | | The Binding of Isaac: Rebirth
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| 363. | Cheating with Glowing Hour Glass! Jacob and Esau to Delirium! | 14 | | The Binding of Isaac: Rebirth
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| 364. | LOW HP FLEX! Tainted Maggy insane run! | 14 | | The Binding of Isaac: Rebirth
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| 365. | This Mod Adds New Planetariums With Bosses! | 93 | | The Binding of Isaac: Rebirth
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| 366. | Satisfying brimstone! Judas to Lamb | 13 | | The Binding of Isaac: Rebirth
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| 367. | 3 Planetarium Items in 1 Run! My Isaac broke the game! | 13 | | The Binding of Isaac: Rebirth
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| 368. | GOODBYE BITRATE! Tainted Isaac PC-breaking run! | 13 | | The Binding of Isaac: Rebirth
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| 369. | What can I get? Tainted Azazel chaos start! | 12 | | The Binding of Isaac: Rebirth
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| 370. | HUGE SWORD! Tainted Lilith mega insane run! | 12 | | The Binding of Isaac: Rebirth
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| 371. | INFINITE REROLLS? Tainted Bethany madness! | 12 | | The Binding of Isaac: Rebirth
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| 372. | MEGA MUSH! Tainted Lost to Mother #6 | 12 | | The Binding of Isaac: Rebirth
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| 373. | Is this combo actually good? Cain to Satan | 12 | | The Binding of Isaac: Rebirth
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| 374. | A Wrong Choice? Lilith's Glitched (Cursed) Crown! | 11 | | The Binding of Isaac: Rebirth
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| 375. | The Razor Queen! Eve to Mother | 11 | | The Binding of Isaac: Rebirth
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| 376. | This New Character Has The Craziest Stats! Adam Gameplay! | 123 | | The Binding of Isaac: Rebirth
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| 377. | True immortality??? Tainted Lost to Mother #5 | 11 | | The Binding of Isaac: Rebirth
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| 378. | This is getting too tough... Tainted Lost to Mother (behind the scenes) | 11 | | The Binding of Isaac: Rebirth
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| 379. | Champion Lost Is Extremely Hard... | 71 | | The Binding of Isaac: Rebirth
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| 380. | Best Ludovico Synergy? Cain to Mother | 9 | | The Binding of Isaac: Rebirth
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| 381. | This New Character Has CRAZY Synergies! Sheriff Gameplay! | 85 | | Sheriff
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| 382. | This New Rune Gives Craziest Stats Ever! | 82 | | The Binding of Isaac: Rebirth
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| 383. | I Found A New Ultra Rare Isaac Miniboss! | 119 | | The Binding of Isaac: Rebirth
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| 384. | The Painful Truth About Tarnished Lost... | 149 | |
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| 385. | These New Alternative Minibosses Are CRAZY! | 337 | |
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| 386. | I Tried Best Multishot Item In The Game! It's CRAZY! | 86 | |
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| 387. | This New Dice Literally Broke My Game! | 70 | | The Binding of Isaac
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| 388. | How I Shot Giant Rockets As Tainted Lost! | 79 | |
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| 389. | I Opened Every Single Room In Isaac With This New Item! | 274 | | The Binding of Isaac: Rebirth
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| 390. | This New Playable Dead Isaac Is Insane! | 198 | | The Binding of Isaac: Rebirth
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| 391. | This Secret Isaac Challenge WIll Blow Your Mind! | 145 | | The Binding of Isaac: Rebirth
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| 392. | This New Character Gets The WORST Items Only! Tainted Bandit Gameplay! | 114 | | Bandits
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| 393. | This New Dice Completely Broke My Game! | 113 | |
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| 394. | I Tried The Most Intense Challenge In Isaac History... | 58 | | The Binding of Isaac: Rebirth
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| 395. | I Finally Found New D6! It's Too Evil... | 80 | |
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| 396. | This New Spider Character Is Too Toxic! | 105 | |
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| 397. | These New Greedier Bosses Are Absolutely Incredible! | 108 | |
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| 398. | This New Cursed Room Gave Me The Best Items! | 115 | |
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| 399. | This Trinket Adds Unique Effects For Every Character! | 113 | |
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| 400. | Tainted Adam Is Finally Out! He's Extremely BROKEN! | 137 | |
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