| 1. |  Reinc | 3:46:33 | Toxic Crusaders (NES) full playthrough | 38:40 |
| 2. |  DarkEvil87's Longplays | 2:57:02 | Toxic Crusaders - DarkEvil87's Longplays - Full Longplay (NES) | 31:39 |
| 3. |  The Mexican Runner | 2:08:32 | 139/714 Toxic Crusaders - NESMania | 2:08:32 |
| 4. |  NintendoComplete | 1:23:29 | Toxic Crusaders (Genesis) Playthrough - NintendoComplete | 51:22 |
| 5. | EctogamesTV | 1:16:38 | Toxic Crusaders Demo | Full Playthrough | 2 | 40:31 |
| 6. |  Longplay Center | 1:13:33 | Toxic Crusaders (Genesis) Playthrough [4K] | 44:04 |
| 7. | Super Omnibox | 1:11:46 | Random Retro Roulette ~ The Games Were Inside Us All Along | 1:11:46 |
| 8. | Eric Corp Incorporated | 58:48 | Toxic Crusaders (Genesis / Mega Drive) Playthrough | 58:48 |
| 9. | Media Pool | 57:18 | Toxic Crusaders (Genesis) Playthrough longplay video game | 57:18 |
| 10. | Mr. Killa KareBear | 50:34 | Mr. KKB Plays Next Fest 2023 - Toxic Crusaders Demo Ep.2 | 27:38 |
| 11. | MEGADAN29 | 49:54 | Toxic Crusaders Playthrough 1 cc Sega Genesis | 49:54 |
| 12. | WarriorsOfXalnada | 38:40 | Toxic Crusaders Nes Nintendo Full Playthrough | 38:40 |
| 13. | World of Longplays | 38:40 | NES Longplay [638] Toxic Crusaders | 38:40 |
| 14. |  BRGKasumi77 MAIN CHANNEL | 32:14 | Toxic Crusaders (NES) Playthrough with cheats | 32:14 |
| 15. | A & C Games | 29:05 | Toxic Crusaders NES Deathless Complete Playthrough - Part 3 | 9:21 |
| 16. |  Esh Plays | 26:51 | Toxeriffic! | Esh Plays TOXIC CRUSADERS (Demo) | 26:51 |
| 17. |  Black_Stark2 | 25:48 | A Cartoonish and Action-packed Couch Co-op Beat 'em Up | Toxic Crusaders demo | 25:48 |
| 18. | Tudututu | 21:34 | Beat them with the help of radioativity | Toxic Crusaders | 21:34 |
| 19. | PlayDHDGaming | 21:03 | Toxic Crusaders Demo Playthrough | 21:03 |
| 20. | SantaAzulCTZN | 20:43 | Toxic Crusaders Demo Playthrough | 20:43 |
| 21. |  Kiss My Robot | 20:06 | Toxic Crusaders (2023) - PC Demo - Full Playthrough | 20:06 |
| 22. | Waffle Bros | 19:22 | WILL THIS BE THE GROSSEST GAME EVER??? | Let's Play Toxic Crusaders (Nextfest Demo) | 19:22 |
| 23. | Geeks and Nerds | 18:49 | Pablo Plays - Toxic Crusaders (Demo) | 18:49 |
| 24. | TurtlePizzaPower's Gaming & Entertainment | 18:29 | Toxic Crusaders (2023) - Full Demo Playthrough (4KHD) | 18:29 |
| 25. | TheInnocentSinful | 17:12 | Toxic Crusaders (PC) Demo Playthrough | 17:12 |
| 26. | Toxcyn | 9:31 | Toxin Plays Toxic Crusader Demo! | 9:31 |
| 27. | OnlyLevelOne | 7:06 | Toxic Crusaders - NES - Only Level One | 7:06 |
| 28. | STUNT_MK | 5:26 | Good&Evil Gaming! Let's Play "Toxic Crusaders"! | 5:26 |
| 29. | 10 Minute Gamer | 4:55 | 10MG Plays Toxic Crusaders on NES | 4:55 |
