| 4DSnake (2019) | 11 | 2 |
| 4P Ping-Pong (2012) | 336 | 2 |
| 4Prot (2021) | 0 | 0 |
| 4Sight (2019) | 28,270 | 5 |
| 4Tacos (2023) | 16 | 2 |
| The 4th Coming (1999) | 50,473 | 67 |
| 4th Era - The RuneChild (2025) | 0 | 0 |
| 4th Generation Warfare (2022) | 350,007 | 114 |
| 4th Super Robot Wars (1995) | 7,195,021 | 4,579 |
| 4x4 Evo (2000) | 288,518 | 346 |
| 4x4 Evo 2 (2001) | 715,132 | 549 |
| 4x4 Hummer (2009) | 644,055 | 106 |
| 4x4 Off-Road Racing (1987) | 324,512 | 162 |
| 4X4 PROGRESS (2025) | 0 | 0 |
| 5 A Day Adventures (1993) | 11,730 | 21 |
| 5 Days a Stranger (2003) | 2,924,494 | 528 |
| 5 Dice (2025) | 9,171 | 6 |
| 5 in 1 Solitaire (2010) | 2,515 | 16 |
| 5 Spots (2003) | 23,491 | 50 |
| 5 Spots II (2003) | 10,005 | 10 |
| 5 Spots Party (2009) | 20,979 | 17 |
| 5 Star Fishy (2026) | 0 | 0 |
| 5 Star Miami Resort (2019) | 8,923 | 10 |
| 5 Star Rio Resort (2017) | 10,320 | 23 |
| 5-in-1 Arcade Hits (2010) | 18,834 | 21 |
| 5-Letter-Kruiswoord (1990) | 163 | 1 |
| 50 Cent: Blood on the Sand (2009) | 19,124,436 | 2,093 |
| 50 Cent: Bulletproof (2005) | 12,058,491 | 1,746 |
| 50 Classic Games (2009) | 23,922 | 48 |
| 50 Mission Crush (1984) | 17,052 | 60 |
| 50 Pinch Barrage!! (2024) | 19,604 | 23 |
| 500 CALIBER CONTRACTZ (2025) | 25,393 | 36 |
| 500 cc Grand Prix (1986) | 24,647 | 33 |
| 505 Tangram (2011) | 729 | 3 |
| 51:22:51 (2023) | 394 | 3 |
| 5D Chess with Multiverse Time Travel (2020) | 9,931,903 | 901 |
| 5omeday (2026) | 397 | 4 |
| 5th Fleet (1994) | 4,725 | 10 |
| 5th Gear (1988) | 12,104 | 49 |
| 6 Feet Behind (2021) | 54 | 4 |
| 6 Inch My Darling (1998) | 14,296 | 12 |
| 6 Seasons and a Game (2021) | 37,141 | 49 |
| 6-in-1 IQ Scale Bundle (2018) | 16,145 | 23 |
| 6-Mon Adventure (2022) | 1,400 | 20 |
| 6-Pak (1995) | 73,091 | 86 |
| 6-Sided Stories (2024) | 177 | 5 |
| 60 BPM (2025) | 0 | 0 |
| 60 Parsecs! (2018) | 130,130,867 | 3,973 |
| 60 Seconds! (2015) | 1,190,632,580 | 12,484 |
| 60 Seconds! Reatomized (2019) | 267,412,087 | 6,836 |
| 6180 the moon (2014) | 131,133 | 150 |
| 63 Days (2024) | 268,763 | 305 |
| 64 de Hakken!! Tamagotchi: Minna de Tamagotchi World (1997) | 461,574 | 296 |
| 64 Hanafuda: Tenshi no Yakusoku (1999) | 73,148 | 35 |
| 64 Trump Collection: Alice no Waku Waku Trump World (1998) | 5,043 | 13 |
| 64.0 (2017) | 3,482,701 | 732 |
| 64th Street: A Detective Story (1991) | 526,326 | 868 |
| 687 Days on Mars (2026) | 21 | 2 |
| 688 Attack Sub (1989) | 146,875 | 114 |
| 69 Days After (2025) | 0 | 0 |
| 69 Summon Succubus (2022) | 0 | 0 |
| 7 Billion Humans (2018) | 5,126,144 | 1,435 |
| 7 Blades (2000) | 149,943 | 277 |
| 7 Colors (1991) | 317,090 | 40 |
| 7 Days a Skeptic (2004) | 1,896,232 | 306 |
| 7 Days Blood Moons (2025) | 657,129 | 250 |
| 7 Days to Die (2013) | 2,594,232,047 | 1,092,054 |
| 7 Days to End with You (2022) | 5,829,966 | 3,054 |
| 7 Days To Save The World (2022) | 3,781 | 1 |
| 7 Days To Think About It (2026) | 0 | 0 |
| 7 days with Death (2017) | 0 | 0 |
| 7 Dni a 7 noci (1994) | 0 | 0 |
| 7 Minutes in Hell (2024) | 0 | 0 |
| 7 Sins : Lost in Labyrinth (2023) | 59,240 | 51 |
| 7 Wonders 2 (2007) | 51,653 | 38 |
