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Genocide Run involves killing every possible NPC in Dark Souls within a single playthrough. This does not include characters such as Frampt, who cannot be killed. It also does not necessarily mean killing NPCs as soon as they are first encountered, as it is sometimes necessary to follow a character's questline for another character to appear.

NPCs in Part 9:

-Xanthous king Jeremiah: a fairly simple scripted invasion and he'll hollow after you've beaten him.

all Dark Souls videos:    • First time playing Dark Souls [part 1]