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Here's how to fix Mouse pointer disappears on the Second Monitor on Windows. Run Avast Driver Updater@ https://www.anrdoezrs.net/click-7952654-14577796 to keep your device drivers up-to-date, easily & effectively.

Here are some troubleshooting steps to try when your mouse cursor disappears on a second monitor in Windows:

- Restart your computer to reset any graphical glitches.

- Make sure your graphics drivers are up to date, especially for the video card driving the second display. Outdated drivers can cause mouse issues.

- Toggle between extending and duplicating the desktops. Sometimes this resets the mouse curser.

- Go to Control Panel - Hardware and Sound - Devices and Printers and check that both monitors are set up properly.

- Adjust the screen resolution and refresh rate of the second monitor. An incompatible setting could make the cursor invisible.

- Check if the second monitor works properly by swapping which one is set as the main display.

- Try unplugging the second monitor from power and video source for 10 seconds and reconnect.

- Open the Mouse properties in Control Panel and alter the pointer schemes to refresh the cursor.

- Run a full malware scan to rule out any malware causing the issue.

- As a last resort, uninstall and reinstall your graphics card drivers cleanly, especially if the issue started after a driver update.

It's likely a software issue that can be corrected.