The uppercut invulnerability exploit (Game Freak's 1994 Pulseman) (warning: flashing lights)
In Pulseman, there is an uppercut move with an exploit where it makes Pulseman invulnerable while using it. It can make boss battles (including the final boss) trivial. You can keep spamming it under Doc Waruyama's hands to defeat him. It might not be a glitch (unless someone analyzes the code to test it) but I thought it was suited to this channel.
Pulseman is a formally Japan-only Mega Drive game by Game Freak the creators of Pokémon before Pokémon Red/Green/Blue, and re-released for Wii Shop Channel and Sega Channel and is now available on Nintendo Switch Online.
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Pulseman Statistics For Evie (ChickasaurusGL) 🌺
Currently, Evie (ChickasaurusGL) 🌺 has 852 views for Pulseman across 1 video. Less than an hour worth of Pulseman videos were uploaded to his channel, making up less than 0.02% of the total overall content on Evie (ChickasaurusGL) 🌺's YouTube channel.