| Eurofighter Typhoon (2001) | 958,664 | 382 |
| Europa 1400: The Guild (2002) | 1,183,270 | 435 |
| Europa Universalis (2000) | 63,805,530 | 23,577 |
| Europa Universalis II (2001) | 507,502 | 259 |
| Europa Universalis III (2007) | 11,654,653 | 6,602 |
| Europa Universalis IV (2013) | 1,101,320,269 | 279,212 |
| Europa Universalis: Crown of the North (2000) | 76,040 | 15 |
| Europa Universalis: Rome (2008) | 0 | 0 |
| Europe Ablaze (1985) | 97 | 1 |
| Europe Racer (2001) | 67,275 | 100 |
| European 5-A-Side (1988) | 700 | 8 |
| European Air War (1998) | 120,676 | 77 |
| European Championship 1992 (1992) | 17,483 | 26 |
| European Club Soccer (1992) | 182,296 | 125 |
| European Conqueror X (2019) | 10,620 | 3 |
| European Football Dynasty 2023 (2022) | 5,761 | 10 |
| European Games (1986) | 175,201 | 26 |
| European Mystery: Flowers of Death (2015) | 33,198 | 51 |
| European Mystery: Scent of Desire (2013) | 918,114 | 105 |
| European Mystery: The Face of Envy (2014) | 43,292 | 62 |
| European Soccer Challenge (1990) | 11,674 | 35 |
| European Super League (2001) | 10,141,071 | 389 |
| European Superleague (1990) | 1,143 | 9 |
| European War (2009) | 8,450,501 | 1,547 |
| European War 4 : Napoleon (2014) | 3,230,604 | 660 |
| European War 5:Empire-Strategy (2016) | 535,589 | 389 |
| European War 6: 1914 - WW1 SLG (2019) | 1,416,621 | 1,205 |
| Euryale's Gambit (2022) | 5,904 | 1 |
| Evade (2021) | 111,728,705 | 3,609 |
| Evan's Remains (2020) | 2,593,206 | 1,191 |
| Evander Holyfield's Real Deal Boxing (1992) | 397,089 | 544 |
| Evangeline's Defense (2022) | 14 | 1 |
| Evasion (2018) | 2,940,877 | 548 |
| Evasive Space (2009) | 19,568 | 25 |
| Eve Burst Error Plus (2003) | 57,056 | 339 |
| EVE Echoes (2020) | 21,043,702 | 10,743 |
| Eve of Calamity (2024) | 41 | 2 |
| Eve of Souls: Static Pod (2019) | 14,549 | 12 |
| EVE Online (2003) | 664,500,712 | 95,378 |
| EVE: Gunjack (2016) | 45,585 | 42 |
| EVE: New Generation (2006) | 5,027 | 38 |
| Eve: Rebirth Terror (2019) | 87,080 | 114 |
| EVE: The Fatal Attraction (2001) | 12,385 | 89 |
| EVE: The Lost One (1998) | 73,718 | 148 |
| Eve: Valkyrie (2016) | 14,954,097 | 2,787 |
| Evel Knievel (1999) | 440,743 | 111 |
| Evelyn's Adventure (2023) | 536 | 4 |
| Even For Eternia (2019) | 1,480 | 13 |
| The Even More Incredible Machine (1993) | 239,691 | 342 |
| Even the Ocean (2016) | 294,121 | 438 |
| Evening Star (1987) | 257,923 | 36 |
| Evening Star (2018) | 14,297 | 13 |
| Evening Starter (2021) | 3,176 | 8 |
| Evening Surprise (2017) | 6,520 | 30 |
| Evenness Sensory Space (2018) | 0 | 0 |
| Event 0 (2016) | 10,336,584 | 697 |
| Event Race (2024) | 24,181 | 118 |
| Eventide 2: The Sorcerers Mirror (2016) | 193,109 | 440 |
| Eventide 3: Legacy of Legends (2017) | 785,046 | 412 |
| Eventide Night (2017) | 1,372 | 2 |
| Eventide: Slavic Fable (2016) | 2,344,575 | 1,054 |
| The Events at Unity Farm (2023) | 3,592 | 18 |
| Ever 17: The Out of Infinity (2011) | 1,773,467 | 1,603 |
| Ever Forward (2020) | 2,338,039 | 710 |
| Ever Oasis (2017) | 7,032,326 | 2,245 |
| Ever Seen A Cat? 2 (2022) | 559 | 12 |
| Ever Seen A Cat? 3 (2022) | 664 | 9 |
| Everafter Falls (2024) | 180,169 | 562 |
| Everblade (2022) | 19,753 | 83 |
| Everblue (2001) | 1,562,195 | 598 |
| Everblue 2 (2002) | 148,954 | 141 |
| Everdell (2022) | 2,990,274 | 581 |
| Everdine - A Lost Girl's Tale (2022) | 18,874 | 28 |
| Everdream Valley (2023) | 1,189,899 | 3,064 |
| Everest Ascent (1983) | 2,483 | 3 |
