| Empire of Ember (2021) | 359,837 | 149 |
| Empire of Sin (2020) | 23,077,661 | 7,724 |
| Empire of the Ants (2000) | 3,648,530 | 277 |
| Empire of the Gods (2016) | 7,272 | 19 |
| Empire of the Over-Mind (1981) | 1,381 | 5 |
| Empire TV Tycoon (2015) | 1,047,864 | 536 |
| Empire! (1986) | 374,200,041 | 7,719 |
| Empire: Total War (2009) | 152,629,691 | 37,379 |
| Empire: Wargame of the Century (1987) | 18,141 | 19 |
| Empires Apart (2018) | 2,404,407 | 410 |
| Empires in Ruins (2021) | 212,615 | 163 |
| Empires of the Undergrowth (2017) | 164,543,954 | 6,076 |
| Empires Shall Fall (2023) | 33,618 | 111 |
| Empires: Dawn of the Modern World (2003) | 536,668 | 491 |
| Emplacement (2023) | 499,871 | 311 |
| Empress of the Deep: The Darkest Secret (2010) | 469,115 | 57 |
| Empty War (2022) | 4,611 | 5 |
| Empty. (2020) | 26,011,461 | 1,933 |
| Empyreal Dawn (2023) | 0 | 0 |
| Empyrion Galactic Survival (2020) | 73,106,295 | 72,450 |
| EmyLiveShow: Dragon & Mistresses Tale (2024) | 0 | 0 |
| En Route: Space (2022) | 3,917 | 9 |
| Encased (2019) | 8,492,714 | 3,850 |
| Encaved (2007) | 155 | 4 |
| Enchanted (2007) | 82,086,597 | 4,932 |
| Enchanted Arms (2006) | 1,938,371 | 2,280 |
| Enchanted Blacksmith (2023) | 127,872 | 6 |
| Enchanted Land (1990) | 57,263 | 58 |
| Enchanted Path (2018) | 1,353 | 6 |
| The Enchanted World (2019) | 401,238 | 290 |
| Enchanter (1983) | 1,005,969 | 422 |
| The Enchanting Islands (2009) | 7,949 | 17 |
| Enclave (2002) | 6,283,169 | 3,089 |
| Enclave: Shadows of Twilight (2012) | 35,967 | 6 |
| Encleverment Experiment (2009) | 8,373 | 11 |
| Encodya (2021) | 695,821 | 1,677 |
| Encounter (1983) | 2,187,051 | 1,308 |
| Encyclopedia of War: Ancient Battles (1988) | 1,678 | 13 |
| The End Is Nigh (2017) | 18,666,809 | 4,981 |
| The End o,,,o (2017) | 3,411 | 16 |
| The End of an Actress (2020) | 1,157 | 2 |
| The End of an Age: Fading Remnants (2019) | 2,353 | 10 |
| End of Lines (2023) | 93,719 | 95 |
| End Of The Mine (2016) | 248,420 | 33 |
| End of this World (2021) | 7,876 | 4 |
| End of Twilight (2003) | 15,668 | 18 |
| End of War 1945 (2020) | 3,648 | 14 |
| End Space (2016) | 1,320,077 | 396 |
| End War RTS (2018) | 0 | 0 |
| Endeavor (2010) | 13,057,531 | 1,295 |
| ENDER LILIES: Quietus of the Knights (2021) | 28,734,336 | 38,248 |
| ENDER MAGNOLIA: Bloom in the mist (2024) | 218,004 | 360 |
| Enderal: Forgotten Stories (2019) | 5,434,085 | 9,350 |
| Endgame: Road To Salvation (2021) | 62,956 | 13 |
| Endgame: Singularity (2005) | 12,379 | 7 |
| Endgame: Syria (2012) | 4,618 | 6 |
| Endings (2021) | 61,183,929 | 2,447 |
| Endless Ages (2003) | 8,949 | 12 |
| Endless Apocalypse (2023) | 139 | 6 |
| Endless ATC (2017) | 8,795 | 24 |
| Endless Bounty (2020) | 10,024 | 7 |
| Endless Dark (2023) | 82,403 | 20 |
| Endless Dungeon (2023) | 12,428,519 | 2,841 |
| Endless Engines (2022) | 19,448 | 21 |
| Endless Escape (2020) | 2,421,878 | 429 |
| Endless Express (2016) | 842,032 | 61 |
| Endless Fables 2: Frozen Path (2017) | 125,403 | 216 |
| Endless Fables 3: Dark Moor (2018) | 89,269 | 249 |
| Endless Fables 4: Shadow Within (2019) | 100,279 | 209 |
| Endless Fables: The Minotaur's Curse (2016) | 181,660 | 351 |
| Endless Firepower (2021) | 544 | 6 |
| The Endless Forest (2005) | 221,773 | 117 |
| Endless Jade Sea -Midori no Umi (2019) | 1,255 | 13 |
| The Endless Journey (2018) | 10,131,703 | 1,409 |
| Endless Knight (2019) | 4,473 | 46 |
