| Euro Truck Simulator 2 (2012) | 8,828,441,958 | 1,498,262 |
| Eurobi Racing (2018) | 51 | 2 |
| Eurofighter Typhoon (2001) | 1,263,362 | 413 |
| Europa 1400: The Guild (2002) | 1,348,389 | 449 |
| Europa Universalis (2000) | 65,967,504 | 24,011 |
| Europa Universalis II (2001) | 520,913 | 263 |
| Europa Universalis III (2007) | 11,667,013 | 6,649 |
| Europa Universalis IV (2013) | 1,112,210,434 | 283,044 |
| Europa Universalis V (2025) | 25,221,354 | 6,645 |
| Europa Universalis: Crown of the North (2000) | 76,044 | 15 |
| Europa Universalis: Rome (2008) | 2,467,372 | 429 |
| Europe Ablaze (1985) | 97 | 1 |
| Europe Racer (2001) | 67,443 | 107 |
| European 5-A-Side (1988) | 700 | 8 |
| European Air War (1998) | 120,894 | 81 |
| European Championship 1992 (1992) | 17,483 | 26 |
| European Club Soccer (1992) | 184,037 | 129 |
| European Conqueror X (2019) | 10,620 | 3 |
| European Football Dynasty 2023 (2022) | 5,761 | 10 |
| European Games (1986) | 185,534 | 27 |
| European Mystery: Flowers of Death (2015) | 33,198 | 51 |
| European Mystery: Scent of Desire (2013) | 918,168 | 107 |
| European Mystery: The Face of Envy (2014) | 43,295 | 62 |
| European Soccer Challenge (1990) | 11,691 | 36 |
| European Super League (2001) | 10,155,236 | 391 |
| European Superleague (1990) | 1,143 | 9 |
| European War (2009) | 8,470,461 | 1,549 |
| European War 4 : Napoleon (2014) | 3,237,846 | 696 |
| European War 5:Empire-Strategy (2016) | 535,656 | 389 |
| European War 6: 1914 - WW1 SLG (2019) | 1,416,651 | 1,207 |
| Euryale's Gambit (2022) | 5,904 | 1 |
| Eva Platformer (2025) | 0 | 0 |
| Eva's Hook (2025) | 0 | 0 |
| Evade (2021) | 112,679,629 | 3,783 |
| Evan's Remains (2020) | 2,595,460 | 1,238 |
| Evander Holyfield's Real Deal Boxing (1992) | 403,789 | 557 |
| Evangeline's Defense (2022) | 14 | 1 |
| Evard The Hermit: Through Fears (2026) | 0 | 0 |
| Evasion (2018) | 2,956,798 | 571 |
| Evasive Space (2009) | 19,584 | 25 |
| Eve Burst Error Plus (2003) | 58,258 | 354 |
| EVE Echoes (2020) | 21,174,674 | 10,789 |
| Eve of Calamity (2024) | 41 | 2 |
| Eve of Souls: Static Pod (2019) | 14,549 | 12 |
| EVE Online (2003) | 675,912,876 | 98,599 |
| EVE: Gunjack (2016) | 45,601 | 42 |
| EVE: New Generation (2006) | 5,031 | 38 |
| Eve: Rebirth Terror (2019) | 87,118 | 114 |
| EVE: The Fatal Attraction (2001) | 12,469 | 89 |
| EVE: The Lost One (1998) | 82,250 | 177 |
| Eve: Valkyrie (2016) | 14,954,413 | 2,787 |
| Evel Knievel (1999) | 441,035 | 116 |
| Evelyn's Adventure (2023) | 536 | 4 |
| Even For Eternia (2019) | 1,480 | 13 |
| The Even More Incredible Machine (1993) | 239,820 | 351 |
| Even the Ocean (2016) | 294,453 | 453 |
| Even20: The Interference of Parallels (2025) | 0 | 0 |
| Evening Star (1987) | 258,538 | 36 |
| Evening Star (2018) | 14,316 | 14 |
| Evening Starter (2021) | 3,176 | 8 |
| Evening Surprise (2017) | 6,520 | 30 |
| Evenness Sensory Space (2018) | 0 | 0 |
| Event 0 (2016) | 10,342,215 | 701 |
| Event Race (2024) | 24,289 | 124 |
| Eventide 2: The Sorcerers Mirror (2016) | 194,713 | 442 |
| Eventide 3: Legacy of Legends (2017) | 785,189 | 413 |
| Eventide Night (2017) | 1,372 | 2 |
| Eventide: Slavic Fable (2016) | 2,431,676 | 1,081 |
| The Events at Unity Farm (2023) | 3,595 | 18 |
| Ever 17: The Out of Infinity (2011) | 1,803,445 | 1,632 |
| Ever Forward (2020) | 2,338,156 | 711 |
| Ever Oasis (2017) | 7,056,069 | 2,266 |
| Ever Seen A Cat? 2 (2022) | 559 | 12 |
| Ever Seen A Cat? 3 (2022) | 664 | 9 |
| Ever War (2025) | 17 | 2 |
