| 1. |  Polygon | DEFCON scares me and science says it will scare you too | 4,356,401 | |
| 2. | Sybert | Massive 3v3 on DEFCON 6 - Generals Evolution | 199,935 | |
| 3. | Drew Durnil | What if every continent used nukes until nothing was left? (DEFCON) | 154,005 | |
| 4. | CptObviousKyle | How To Play- Defcon | 95,264 | Guide |
| 5. | Culveyhouse | How to Play DEFCON Demo Version (A Full 1v1 Game in 1080p HD) | 60,881 | |
| 6. | Waypoint | Playing DEFCON with a Nuclear Arms Expert | 56,391 | |
| 7. | Nookrium | ICBM - (World War Real-Time Strategy Game) | 56,016 | |
| 8. | CptObviousKyle | Defcon (Nuclear Warfare Simulator) | 54,897 | |
| 9. | Best War Games Channel | SIMULATOR OF NUCLEAR WAR! Tactical Strategy DEFCON! The game on the PC about the Apocalypse | 43,825 | |
| 10. | Nookrium | ICBM - (World Destroying Real Time Strategy Game) | 39,410 | |
| 11. | CptObviousKyle | Defcon 3v3 (Multiplayer) | 34,637 | |
| 12. | The Historical Gamer | ICBM - A New Game - Co-op Gameplay with TortugaPower - Part 1 | 23,148 | |
| 13. | MasterofRoflness | GLOBAL NUCLEAR GENOCIDE! Nuclear Warfare Real Time Strategy Game - Defcon Gameplay | 21,012 | |
| 14. | Culveyhouse | DEFCON: Everybody Dies 1v1 Multiplayer Match, EzioCroft vs. CulveyNuke | 14,818 | |
| 15. | Mitchell Godsend | ICBM - The Game DEFCON Players Have Been Waiting For | 14,708 | |
| 16. | TortugaPower | ICBM (PC game) | Coop Multiplayer w/ THG - 01 - Destroyer All-In | 13,553 | |
| 17. | MasterofRoflness | A Game that Lets me start WW3 and Nuke Everyone Defcon | 12,918 | |
| 18. | Nookrium | First Strike: Final Hour - (Real Time Strategy Nuclear War Game) | 11,967 | |
| 19. | Dodge Them All | DEFCON: EVERYBODY DIES | 11,271 | |
| 20. | Sybert | Explosive Super Weapon - DEFCON 6 - Generals Evolution | 10,229 | |
| 21. | MasterofRoflness | Defcon Gameplay - World War Three Simulator | 9,383 | |
| 22. | Sybert | Burning Hot 2v2v2 on DEFCON 6 - Generals Evolution | 8,904 | |
| 23. | finalgirlrun | DEFCON East vs. West Nuclear War Timelapse | 7,735 | |
| 24. | The Historical Gamer | ICBM – First Impressions – Free Download (Steam Festival) – Part 1 | 7,321 | First Impressions |
| 25. | The Historical Gamer | ICBM - Out Now! - Eve of Destruction - Co-op with TortugaPower - Part 2 | 6,828 | |
| 26. | Gardiner Bryant | OpenRCT2 | Open Source Gaming Showcase | 6,814 | |
| 27. | TortugaPower | ICBM (PC game) | Coop Multiplayer w/ THG - 02 - Road to Armageddon | 6,611 | |
| 28. | Really Slow Motion | Really Slow Motion & Giant Apes - Defcon (Atmospheric Dramatic Trailer Music) | 6,071 | |
| 29. | Gameplay Twist | How To Install Defcon Mods | 5,240 | Tutorial |
| 30. | TortugaPower | ICBM (PC game) | Coop Multiplayer w/ THG - 03 - Mutual Destruction | 4,351 | |
| 31. | The Historical Gamer | ICBM – Nuclear War! – Free Download (Steam Festival) – Part 2 | 3,921 | |
| 32. | Real Strategy Gaming | Ra2 Defcon 6 Usa vs French Center Tactic | 3,470 | |
| 33. | itrSIMPLE | Red Bull Madness | POWER HOUR | Defqon.1 Weekend Festival 2019 | Reaction | 3,143 | |
| 34. | The Historical Gamer | ICBM – Gameplay – Nuking Friends - Wolfpack345 – TortugaPower – Finnishjager – Part 2 | 2,916 | |
| 35. | Effing Controller | Effing Around in DEFCON with Tailmange! | 2,850 | |
| 36. | The Historical Gamer | New Game Announced! | ICBM: Escalation | 2,423 | |
| 37. | Arthur Huynh | Defcon - Merry Christmas Achivement (Steam Gift Grab) | 1,827 | |
| 38. | Sleepyjo2 | What Have We Done!? Defcon - Everybody Dies | 1,756 | Let's Play |
| 39. | Gameplay Twist | Defcon Genocide Today Mod, also using Deterrence Mod | 1,500 | |
| 40. | Gameplay Twist | Defcon PC Game Mods | 1,486 | |
| 41. | Doughnuts | Zombies 101 :: "Five" 101 :: Pack-A-Punch Tutorial - Raising the DefCon Level | 1,459 | Tutorial |
| 42. | Gameplay Twist | How To Create A Defcon Map Mod, Complete Tutorial with Modsuite | 1,357 | Tutorial |
| 43. | Gameplay Twist | Defcon - Map Mods - Everybody Dies PC Game - Mod List | 1,153 | |
| 44. | Commissar BRO | DEFCON - Let's just Watch the World Burn | 907 | |
| 45. | Mr Cabin Fever | ITS OVER AT THIS POINT #viralshorts | 664 | Walkthrough |
| 46. | Gameplay Twist | Defcon - Style Mods - Everybody Dies PC Game | 661 | |
| 47. | Alexander Williams | Defcon Trailer | 651 | |
| 48. | Emilia | Adept plays DEFCON: Everybody dies - North America - LET IT RAIN NUKES! | 393 | Let's Play |
| 49. | Budgy | DEFCON Funny Moments - Part 1 [Pavlov VR] | 392 | |
| 50. | Tucker Flipz | Best budget balisong trainer | DEFCON Tactical Hex | 388 | |
| 51. | Culveyhouse | Game Demo to Come: DEFCON | 376 | |
| 52. | Bandit | DEFCON Trailer (Fan-Made) | 374 | Preview |
| 53. | Emilia | DEFCON: Everybody dies - Russia - FOR THE MOTHERLAND! | 368 | |
| 54. | Cockney Gamer | Nuclear War Simulation - DEFCON 2022 review | 352 | Review |
| 55. | Last Level Press | Livestream: DEFCON - THE RED BUTTON CALLS TO ME - Pt.1 | 311 | |
| 56. | CommandoX798 | Defcon - Everybody Dies Cold War Situation | 300 | |
| 57. | Guard13007 | This is not the video you wanted | 267 | |
| 58. | PhotonMote | Defcon | It Only Takes One | 252 | |
| 59. | MrNoDStudios | DEFCON w/ Friends | 251 | |
| 60. | Gameplay Twist | Defcon: Everybody Dies, Deterrence Mod Issues | 238 | |
| 61. | Gameplay Twist | PC Defcon Gameplay, Review, Overview, Mods | 212 | Review |
| 62. | TheLoganatorz | Nuking The Soviet Union - DEFCON Gameplay! | 180 | |
| 63. | HalfPastEight | Curtain Call - DEFCON GMV | 172 | |
| 64. | Dragon Goose Games | DEFCON: A Post Apocalyptic Roleplaying System #defcon #ttrpg #roleplayinggames | 167 | |
| 65. | Budgy | DEFCON Funny Moments - Part 2 [Pavlov VR] | 165 | |
| 66. | TheZanzibarMan | [Episode 5] Subterrain PS4 Gameplay [DEFCON] | 164 | |
| 67. | THE STEEL MINDSET | NEW & EXCITING TACTICAL KNIVES - DEFCON TACTICAL KNIFE REVIEW!!!! @defcontactical5538 | 164 | |
| 68. | Gameplay Twist | Defcon Shortcut Keys How To Play | 159 | Tutorial |
| 69. | StrifeZ Gaming | 41st Diaries episode 3: Down time. ((defcon gaming)) | 154 | |
| 70. | Dragon Goose Games | Physical Skills Comp - DEFCON #defcon #dnd #ttrpg #fallout #roleplayinggames | 117 | |
| 71. | Lost Gamer | DEFCOИ (Global Thermonuclear War) – NATO v. Russia and China (AI Plays) | 107 | Let's Play |
| 72. | StrifeZ Gaming | 41st Diaries Episode 2 Part 2 : Wacky stoof happens. ((defcon gaming)) | 85 | Show |
| 73. | Gameplay Twist | Defcon Custom Map Travel Nodes Progression | 83 | |
| 74. | Nerd Sloth | Top 5 Indie Games from 2006 That Changed Gaming Forever | 75 | |
| 75. | Lost Gamer | DEFCOИ (Global Thermonuclear War): Modern Warfare Mod – Western Alliance v. Eastern Pact (AI Plays) | 75 | Let's Play |
| 76. | Encyclopegames | Playstation - War Games - Defcon 1 .flv | 72 | Let's Play |
| 77. | Last Level Press | Livestream: DEFCON - THE RED BUTTON CALLS TO ME - Pt.2 | 66 | |
| 78. | LikeRod | Defcon 1 - Can I Play With Madness - Amiga Demo - HD Quality | 65 | |
| 79. | Gameplay Twist | Defcon Custom Map Mod America Map V2 Larger | 65 | |
| 80. | Little Mac | LET"S PLAY!: DEFCON | 64 | |
| 81. | TheRealStew | "Global Thermonuclear war?" Lets Play 4k S1 Ep4 | Defcon | 60 | Let's Play |
| 82. | The War Room | DEFCON gameplay | 59 | |
| 83. | StrifeZ Gaming | 41st diaries episode 2 finale: The blastening! ((defcon gaming)) | 52 | Show |
| 84. | Gameplay Twist | Defcon Ying-Yang Map Mod, also Deterrence Mod | 51 | |
| 85. | Lost Gamer | DEFCOИ: Modern Warfare Mod – U.S. Alliance v. The World (Cheating Gamer Plays) | 51 | Let's Play |
| 86. | Mr Cabin Fever | COLDLINE FORCES YOU TO STOP A NUKE IN 10 MINUTES ( THE PERFECT GAME ) | 38 | Walkthrough |
| 87. | CoreyPlays | Playing Defcon | LIVE | 36 | |
| 88. | Gangaleng | Diving Into DEFCON: How can I ramp up my kill count? | 33 | |
| 89. | Anthellimus | World War 5 - DEFCON | 32 | |
| 90. | Lenvex | Life in the bunkers - Defcon Gameplay | 23 | |
| 91. | Jason McMaster | DEFCON Chick Vs McMaster - McMaster Perspective | 17 | |
| 92. | Neuel | TFU plays DEFCON! | 14 | |
| 93. | ClapperCraft360 | Defcon: Nuclear Battle Royale | 13 | |
| 94. | Lonewolframbo30 Entertainment | Defcon Nuclear Death Always Happens | 11 | |
| 95. | Studio Mogura | DEFCON - GLOBAL THERMONUCLEAR WAR | 11 | |
| 96. | Petroition | DEFCON | 7 | |
| 97. | MTE | (Full Gameplay) DEFCON [1080p] - No Commentary | 6 | |
| 98. | Blackout650 Gaming | Defcon | 6 | |
| 99. | Studio Mogura | DEFCON - GLOBAL THERMONUCLEAR WAR | 2 | |
| 100. | The One B | The One B Plays Defcon | Plus Amazon and Google Discussion | 1 | |
