Crash Twinsanity - N. Sanity Island (Jungle Bungle) Theme Remix
You're not playing a "Crash" game until you see Cortex gunning down an innocent farmer to steal his power crystal before casually breaking the fourth wall as this theme plays in the background.
Sure, "Twinsanity" has its flaws- numerous glitches, the story being all over the place, and the game being so short- but if there's one thing that wasn't negatively impacted by the game's rushed development, it was the memorable jokes that we got out of it.
In addition to the previously-mentioned joke about Cortex mugging a guy and while the fourth wall, I can't help but think about him mentioning how the spikes broke his fall in Jungle Bungle and that enemy skunk that went on strike in the same level whenever I hear the N. Sanity Island music. Not to mention, this theme plays right before Crash kicks Cortex's ass and turns him into a human snowboard.
Though while the title/N. Sanity Island/Jungle Bungle music has a lot of humorous memories associated with it, I also like it because it perfectly captures the essence of the "Crash Bandicoot" series: upbeat and filled with all of the over-the-top insanity of a Looney Tunes cartoon.