Max Settings, 4xAA, 3440x1440, 1440p Aspect Ratio 21:9, or 2.38:1.
Edit: YouTube must have change something because the video is so dark now. It wasn't like that before!
PC: C2Q Q9300, GF GT 640, 4GB RAM.
Even 3840x2160 is not a problem. Framerate w/o rec. is mostly above 60fps and reaching the limit of 90fps.
Played on hardest difficulty.
The famous RTCW, even nowadays it's still a great game.
Highly recommended, if you still haven't played this game.
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