| 1. | 100 FACTS ABOUT THE BINDING OF ISAAC (The Binding of Isaac Facts & Trivia) | 259,154 | | The Binding of Isaac: Rebirth
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| 2. | TOP 5 OPEN WORLD/FREE ROAMING 3DS GAMES! - Open World / Free Roaming Games for 3DS! | 250,603 | Let's Play | Fantasy Life
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| 3. | TOP 5 FIRST PERSON SHOOTER 3DS GAMES! - FPS / Shooter Games for 3DS! | 238,651 | Let's Play | Metroid Prime: Federation Force
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| 4. | SEXY NEW BOSS?! - ISAAC MODSHOWCASE #6 - The Invocation Circle (NEW BOSS MOIRA!) | 124,938 | Show | The Binding of Isaac: Rebirth
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| 5. | Easy OP Items in Terraria - Fishing Pre-Hardmode Guide Terraria 1.4 | 112,187 | Guide | Terraria
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| 6. | The Binding of Isaac Afterbirth+ LUA Modding Tutorial #1 - Making Passive Item from Scratch! | 68,832 | Tutorial | The Binding of Isaac: Rebirth
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| 7. | The Binding of Isaac Repentance Item Guide - #580 Red Key (IsaacGuru Collab) | 59,140 | Guide | The Binding of Isaac: Rebirth
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| 8. | Enter the Gungeon for Nintendo Switch - REVIEW (SWITCH VS PC WHICH ONE IS BETTER?) | 57,583 | Review | Enter the Gungeon
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| 9. | TOP 5 OPEN WORLD/FREE ROAMING 3DS GAMES! #2 - Open World / Free Roaming Games for 3DS! | 56,048 | Let's Play | The Legend of Zelda: A Link Between Worlds
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| 10. | LIFE SIMULATION GAMES - WHAT ARE THEY & THE HISTORY OF LIFE SIMS - EVERYTHING ABOUT LIFE SIM GAMES | 49,180 | | The Sims 4
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| 11. | The Binding of Isaac: Afterbirth+ 101 - #1: The Basics | 39,574 | Guide | The Binding of Isaac: Rebirth
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| 12. | TOP 10 MOST ANTICIPATED ITEMS IN THE BINDING OF ISAAC REPENTANCE | 28,867 | | The Binding of Isaac: Rebirth
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| 13. | The Binding of Isaac Afterbirth+ LUA Modding Tutorial #7 - CUSTOM CHARACTERS | 26,923 | Tutorial | The Binding of Isaac: Rebirth
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| 14. | The Binding of Isaac: Repentance DLC GUIDE | EVERYTHING YOU NEED TO KNOW ABOUT REPENTANCE DLC | 25,591 | Guide | The Binding of Isaac: Rebirth
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| 15. | DAILY ISAAC AB+ RUN - Mom's Knife + Tech X ?!! | 20,013 | | The Binding of Isaac: Rebirth
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| 16. | The Binding of Isaac: Genesis+ Demonic Descent (Release Date Trailer) | 19,916 | Preview | The Binding of Isaac: Rebirth
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| 17. | 4 NEW SPECIAL CHARACTERS?! - Isaac Modshowcase #2 - Infamy, Rebekah, The Bound & More! | 16,685 | Show | The Binding of Isaac: Rebirth
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| 18. | THE BINDING OF ISAAC HD TEXTURE MOD?! - Isaac Modshowcase #1 (Isaac Realistic Textures Mod) | 15,790 | Let's Play | The Binding of Isaac: Rebirth
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| 19. | TOP 5 BEST ROGUELIKE/ROGUELITE GAMES ON NINTENDO SWITCH | 15,171 | | Away: Journey to the Unexpected
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| 20. | The Binding of Isaac: Afterbirth+ 101 - #2: Floors & Room Types (Binding of Isaac Tips & Tricks) | 14,922 | Guide | The Binding of Isaac: Rebirth
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| 21. | The Binding of Isaac Afterbirth+ Modding Tutorial #2 - Adding Jesus & Sprite Editing | 11,483 | Tutorial | The Binding of Isaac: Rebirth
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| 22. | FIFA 17 PACK FLARE GUIDE - Types of Flares & Tips For Opening Packs! | 11,245 | Guide | FIFA 17
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| 23. | THE BINDING OF ISAAC ICEBERG EXPLAINED | 9,772 | | The Binding of Isaac: Rebirth
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| 24. | Worms W.M.D for Nintendo Switch - REVIEW | 8,203 | Review | Worms W.M.D
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| 25. | Ittle Dew 2+ for Nintendo Switch - REVIEW | 7,036 | Review | Ittle Dew 2
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| 26. | The Binding of Isaac: Afterbirth+ 101 - #3: Curses & More Floors | 6,566 | Let's Play | The Binding of Isaac: Rebirth
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| 27. | FIFA 17 MOHAMED SALAH 93 BOOSTED SCREAM CARD! - THE BEAST - FIFA 17 ULTIMATE TEAM PLAYER REVIEW | 6,468 | Review | FIFA 17
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| 28. | Tetrachromacy - The Binding of Isaac: Genesis+ Items #1 | 6,464 | | The Binding of Isaac
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| 29. | SMOKING WEED IN MINECRAFT?! - #2 Psychedelicraft Mod Showcase (Minecraft Drugs Mod) | 6,396 | Let's Play | Minecraft
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| 30. | Steam Deck Gameplay - Wii Sports Resort (Golf, Bowling, Swordplay & More!) | 6,287 | | Wii Sports Resort
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| 31. | The Binding of Isaac Afterbirth+ LUA Modding Tutorial #3 - Custom Tears & Effects! | 6,206 | Tutorial | The Binding of Isaac: Rebirth
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| 32. | The Binding of Isaac Afterbirth+ LUA Modding Tutorial #6 - CUSTOM ENEMIES FROM SPRITE TO LUA | 6,112 | Tutorial | The Binding of Isaac: Rebirth
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| 33. | TOP 10 Most Obscure Spirits in Super Smash Bros. Ultimate so Far | 5,982 | | Super Smash Bros. Ultimate
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| 34. | TOUR AROUND MY 5 STAR ACNH ISLAND! | Animal Crossing New Horizons 5 Island Tour | 5,943 | | Animal Crossing: New Horizons
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| 35. | The Binding Of Isaac Repentance Bosses | EVERYTHING ABOUT THE NEW BOSSES & NEWS! | 5,859 | | The Binding of Isaac: Rebirth
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| 36. | The Witcher 3 on GPD Win 2 8100Y Revision | 5,640 | | The Witcher 3: Wild Hunt
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| 37. | Broski Plays: Pokemon Sun & Moon - PROFESSOR HUNK?! (Pokemon Sun & Moon Early Gameplay 3DS) | 5,567 | Let's Play | Pokémon Sun and Moon
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| 38. | The Binding of Isaac: Genesis+ Septic Shock! OST #2 - Lost Forever (Basement) | 5,269 | | The Binding of Isaac: Rebirth
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| 39. | The Binding of Isaac Repentance New Exclusive PAX West Gameplay! | 4,661 | | The Binding of Isaac: Rebirth
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| 40. | THE SMASH ULTIMATE ROSTER LEAK WAS FAKE! | 4,515 | | Super Smash Bros. Ultimate
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| 41. | 10 Years of The Binding of Isaac LIVE! w/ Edmund McMillen (Creator of The Binding of Isaac) | 4,420 | | The Binding of Isaac
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| 42. | The Binding of Isaac: Genesis+ Septic Shock! OST #3 - Bodega Malidicon (Cellar) | 4,393 | | The Binding of Isaac: Rebirth
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| 43. | Terraria THE ULTIMATE MODDED LETS PLAY #1 - Tremor, Calamity & 23+ MODS! (Terraria 3.1.5 Modded) | 4,170 | Let's Play | Terraria
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| 44. | The Binding of Isaac Afterbirth+ RAP! - Afterbirth+ Song Parody🎧 | 3,843 | | The Binding of Isaac: Rebirth
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| 45. | Bailey's LIVE reaction to Nintendo Labo trailer. | 3,803 | | Nintendo Labo
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| 46. | The Binding of Isaac Repentance LIVE 24 HOUR LIVESTREAM!! | 3,684 | | The Binding of Isaac: Rebirth
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| 47. | Super Smash Bros. Ultimate DATAMINED?! - 17 NEW CHARACTERS REVEALED!!! (Geno, Banjo&Kazooie & More!) | 3,679 | | Super Smash Bros. Ultimate
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| 48. | World Neverland: Elnea Kingdom Switch LIVESTREAM! | 3,629 | | WorldNeverland - Elnea Kingdom
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| 49. | The Binding of Isaac Afterbirth+ LUA Modding Tutorial #5 - How to Make CUSTOM FAMILIARS | 3,594 | Tutorial | The Binding of Isaac: Rebirth
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| 50. | Super Smash Bros. Ultimate Infinite Assist Trophy Glitch with Rathalos! | 3,477 | | Super Smash Bros. Ultimate
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| 51. | The Binding of Isaac: Repented OST Teaser (Isaac Music Mod) | 3,160 | | The Binding of Isaac: Rebirth
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| 52. | The Binding of Isaac: AFTERBIRTH: SOY MILK + PYROMANIAC + IPECAC + DR FETUS #2 | 3,139 | Let's Play | The Binding of Isaac: Rebirth
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| 53. | FIFA 17 EA REFUNDED 2000$ WORTH OF FIFA POINTS?!⚽😱💰 | 3,108 | | FIFA 17
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| 54. | Garry's Mod on GPD Win 2 8100Y | 2,741 | | Garry's Mod
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| 55. | RAYMAN HINTED IN LATEST DIRECT?! - Super Smash Bros. Ultimate Rumors & Leaks (Smash 5 RUMORS) | 2,722 | | Super Smash Bros. Ultimate
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| 56. | The Binding of Jesus: Holybirth+ Alpha 1.02 Update Video | 2,667 | Let's Play | The Binding of Isaac: Rebirth
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| 57. | 10 Years of The Binding of Isaac Interview - #2 Kilburn (Lead Dev Repentance & Antibirth) | 2,625 | | The Binding of Isaac: Rebirth
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| 58. | NEW REPENTANCE BLOGPOST! - The Binding of Isaac: Repentance Blog Post Discussion | 2,495 | Discussion | The Binding of Isaac: Rebirth
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| 59. | POKEFLOATS RETURNS ALONGSIDE BANDANA WADDLE DEE AND SKULL KID?! SMASH ULTIMATE LEAKED PICTURE | 2,407 | | Super Smash Bros. Ultimate
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| 60. | ARE THE BIG SMASH/NINTENDO CHANNELS LYING TO US?! (RANT) | 2,120 | | Super Smash Bros. Ultimate
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| 61. | Super Smash Bros. Ultimate Lifelight Piano Cover (World of Light Theme) | 2,079 | | Super Smash Bros. Ultimate
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| 62. | Lucifer's Wallet - The Binding of Isaac: Genesis+ Items #2 | 2,032 | | The Binding of Isaac
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| 63. | Making MUSIC with Nintendo Switch JOYCONS?! | 1,990 | | Splatoon 3
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| 64. | The Story Behind the Isaac Collectible EP 2: Ipecac (Legacy of Isaac Items) | 1,973 | Let's Play | The Binding of Isaac: Rebirth
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| 65. | Shops (Tips, Tricks & Strategies) - The Binding of Isaac: Repentance 101 Ep. 4 | 1,961 | Let's Play | The Binding of Isaac: Rebirth
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| 66. | GPD Win 2 Unboxing | 1,934 | |
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| 67. | Draw a Stickman: EPIC 2 Nintendo Switch 7 Min Gameplay | 1,928 | | Draw a Stickman: EPIC 2
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| 68. | WHAT THE FUCK IS OG ISAAC?! - The Binding of Isaac: Wrath of the Lamb VS Rebirth | 1,916 | | The Binding of Isaac
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| 69. | REPENTED 1.6 - FIENDISH UPDATE! OVERVIEW! (Repented Music Mod Fiend Folio Update) | 1,883 | Vlog | The Binding of Isaac: Rebirth
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| 70. | The Binding of Isaac Afterbirth+ LUA Modding Tutorial #4 - Curse Callbacks & Itempools | 1,872 | Tutorial | The Binding of Isaac: Rebirth
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| 71. | Isaac - Super Smash Bros. Ultimate Moveset Speculation Episode 1 | 1,841 | | Super Smash Bros. Ultimate
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| 72. | The Sims 4 on GPD Win 2 8100Y | 1,820 | | The Sims 4
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| 73. | Pallet Town (REIMAGINED) - Map Speed Build RPG Maker XP | 1,747 | | RPG Maker XP
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| 74. | FIFA 17 SBC DOUGLAS COSTA 85 REVIEW - INSANE 5★ DRIBBLER - FIFA 17 ULTIMATE TEAM PLAYER REVIEW | 1,745 | Review | FIFA 17
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| 75. | Achievements - The Binding of Isaac: Genesis+ | 1,726 | Let's Play | The Binding of Isaac
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| 76. | WOW NEW ORIGINAL SPECIAL CHARACTERS?! - Isaac Modshowcase #6 Ulam & The Warden | 1,712 | Show | The Binding of Isaac: Rebirth
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| 77. | OMG THIS IS HERETIC! - Isaac Modshowcase #3 - Heretic Mod | 1,652 | Let's Play | The Binding of Isaac: Rebirth
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| 78. | GPD WIN 2 - The Best Handheld Game Console | 1,636 | | Grand Theft Auto V
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| 79. | Soul Locket - The Binding of Isaac Repentance Item Guide | 1,633 | Guide | The Binding of Isaac: Rebirth
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| 80. | The Story Behind the Isaac Collectible EP 1: Tammy's Head (Legacy of Isaac Items) | 1,623 | Let's Play | The Binding of Isaac: Rebirth
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| 81. | REVIEW - Henry The Hamster Handler (Nintendo Switch) | 1,582 | |
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| 82. | The Binding of Isaac: Repentance Discussion | EVERYTHING WE KNOW ABOUT ASHPIT (NEW ALT MINES FLOOR) | 1,510 | Discussion | The Binding of Isaac: Rebirth
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| 83. | THE BIGGEST MODDED RUN EVER! - 12+ MODPACKS OVER 1000 ITEMS & MORE! | 1,495 | Let's Play | The Binding of Isaac: Rebirth
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| 84. | Memories - The Binding of isaac Genesis+ Demonic Descent OST (Delirium Fight) | 1,360 | |
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| 85. | KING SAUL & THE DRAWN! - AB+ DAILY MODDED RUN #4 | 1,346 | Let's Play | The Binding of Isaac: Rebirth
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| 86. | Morgyn's LIVE reaction to Nintendo Labo trailer. | 1,333 | | Nintendo Labo
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| 87. | 10 Years of The Binding of Isaac Interview - #1 Florian Himsl (Programmer & Co-Founder of Isaac) | 1,312 | | The Binding of Isaac: Rebirth
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| 88. | FIFA 17 - 73 GIOVANNI SIMEONE SILVER IF REVIEW - SON OF DIEGO SIMEONE?! - FUT 17 PLAYER REVIEW! | 1,299 | Review | FIFA 17
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| 89. | The Binding of Isaac Repentance News | Interviews, 3500 Subscribers & More | 1,206 | | The Binding of Isaac: Rebirth
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| 90. | Amazing Link Galaga Boss Item Combo / Meteor Smash - Smash Bros Ultimate | 1,183 | | Super Smash Bros. Ultimate
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| 91. | EVERYTHING ABOUT COSTUMES XML & ANIMATIONS - AB+ Modding Tutorial #7 | 1,155 | Tutorial | The Binding of Isaac: Rebirth
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| 92. | PLEASE HELP ME OUT GUYS! - FORZA HORIZON 3 0x80070005 ERROR!! | 1,150 | Let's Play | Forza Horizon 3
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| 93. | Call of Duty: Black Ops II on GPD Win 2 8100-Y | 1,139 | | Call of Duty: Black Ops II
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| 94. | The Binding of Isaac: Genesis+ Septic Shock! OST #1 - Descendants (Title Screen) | 1,085 | | The Binding of Isaac: Rebirth
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| 95. | POKEMON IN ISAAC?! - The Binding of Isaac Repentance ModShowcase #1 (Eevee: Reunited Mod) | 1,034 | Show | The Binding of Isaac: Rebirth
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| 96. | ALPHABIRTH?! - Isaac ModShowcase #7 - AlphaBirth: A Mom's Closet & All That is Unholy | 1,017 | Let's Play | The Binding of Isaac: Rebirth
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| 97. | Super Smash Bros. Ultimate - Let's TALK TROPHIES (SMASH ULTIMATE TROPHY PREDICTIONS) | 1,006 | Discussion | Super Smash Bros. Ultimate
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| 98. | NEW FUT 17 RATINGS + FIFA 16 COMPARISON! #1 Ft. Bakambu, Salah, Mane & More! | 992 | | FIFA 17
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| 99. | WIN THE BINDING OF ISAAC REBIRTH FOR IOS?! - 1K SUBS GIVEAWAY (Antibirth Run Special!) | 978 | Let's Play | The Binding of Isaac: Rebirth
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| 100. | MARIO IN ISAAC?! - Isaac Modshowcase #5 - The Binding of Mario Starbirth+ & The Binding of Nintendo! | 969 | Show | The Binding of Isaac: Rebirth
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